March 2010

I am 34 years old and in good health overall. I recently noticed a small bb size lump on the right side of the shaft. I went to a urologist who told me I may have Peyronies and advised me to take Vitamin E for 6 months or so and nothing else. He did not seem concerned whatsoever of course I am. I have no pain whatsoever and no curvature that I can notice. Since he told me this, I have been hypercritical about what I see or what I feel but overall, everything looks and feels "normal" to me. Besides the bb sized lump I cannot feel any other hard areas anywhere on the shaft. The lump appeared sometime around January 15, 2010 and at this point, I have seen no change in the size or sensitivity (as its not sensitive). I scheduled another appointment with a urologist who specializes in peyronies. Based on these facts, I wanted to know your opinion on whether you think this sounds like peyronie's?

With no pain or curvature I doubt this is PD. MG

We are a group of researchers at McGill University conducting an ethics approved and federally funded study on male sexuality. As a part of our research we are developing a scale to assess male genital self image as an important part of male sexual health. One of our hypotheses is that changes in male genital shape or function will impact sexuality through their self image. We are presently collecting information about this by having men fill out a short online survey about their genitals and feelings towards them. Would you be willing to post the link to our survey on your site to help us access your population? Our aim is to help better understand male sexuality with the purpose of improving quality of life. Your help would be greatly appreciated. Best Regards, Seth Davis, BA, PhD Candidate McGill University Department of Psychology www.binik-lab.com

Thanks. MG

I am 22 years old and healthy. Over the past year I have watched my sex life continuously get worse. I think I have a masturbation problem. For the past couple years I have usually masturbated at least once a day sometimes more, without lubrication. Recently I have noticed that there is a massive indent on one side of my penis. It is only noticeable when erect or semi erect. When I masturbate I can barely keep an erection. If i stop it goes down instantly. During sex I cant maintain a strong enough erection. It usually just fades during some point or I will somehow ejaculate really fast with a semi hard penis. The appearance is odd and i think i am smaller which is horrible. However, at this point I am just concerned with getting legitimate erections again. I went to a urologist who thinks it is Peyronies but found no evidence of plaques.

Unlikely to be PD at your age, with the absence of plaque. MG

Hello I'm 25 yrs old I think I've had PD for about 8 yrs now, if that is what I have I'm not sure! It is a bend but it's downwards and it may have been because I stopped ejaculation before by pressing on my shaft (I'm not sure if that would cause it)? Either way it's not painful and it's bent down as I said, I've had some Premature ejaculation for a few years now, could PD be the cause and can it make me lose my sexual function, other than the PE problem I seem to be fine. Should I be concerned and see a specialist?

I think that would be a good idea, if for no other reason than to give you some answers. If your problem started at age 17 I would say this is congenital curvature, not PD. MG

My partner has hourglass Peronies and experiences pain with erections. He is 35. It has developed over the last 3 months or so. The hour glass is notable and the bend is about 20 degrees. The penis shaft feels restricted at the top like a rubber band is over it. We have not seen a urologist yet. We are very scared, and feel isolated. QUESTION 1: What are the first steps to reducing the pain, and the curvature - injections? He takes Vit E 400mg every day anyway. Will the pain subside? In most cases? QUESTION 2: I have read that in some cases the pain subsides in the first 6 - 12 months, what is the percentage likelyhood the pain will subside, as the bend is not restricting sexual intercourse? QUESTION 3: From all the reading I have done am I correct in saying that the phases are: penis pain and some curvature - approx a year, followed by a period of stabilisation and pain subsidence, with curvature increasing and getting increasingly curved over time?

If the pain is bad ibuprofen will help. You are right the pain will eventually go away on its own. You may see some increase in curvature over that time. MG

What are the dangers of surgery ?

Depends on the type of surgery, but includes Erectile dysfunction, length loss, sensory loss, or imperfect correction of curvature. MG

I noticed about 4 months ago that I was having painful nocturnal erections. It then transpired into painful intercourse of which I dont have very frequently because of lack of sex drive mainly. I noticed last week that sex was ultra painful and I could feel a pea size hard mass in the middle of the shaft of my penis. I have no curvature or bend but I am still thinking it is peyronies the more I read. I started taking vitamin e and have an appt with a urologist. Is it possible I will never lose penis size or have any curve or is that pretty much a given in the coming months. What to do.

Go see a urologist. Length loss is not a given in every case. MG

Hi, im 30years old, fit active, exercise regularly. Over the last few years i have noticed a gradual "wasting" of my penis. It has become very soft, flaccid and shrunken when not erect. There also appears to be a contracting band or tightening on the shaft towards the end of my penis which can give it a one-sided hour glass shape. i have been to see my GP who thought possibly it may be peyronies disease or some thing similar. I have no pain in my penis and have no trouble getting an erection. There is no deviation/curvature in my erection. However the symptoms are really affecting me and ruining my sex life and relationship. I used to have a normal, "fuller" penis when not erect. When i was younger i was very 'rough' when masturbateing and im concerned i have done long term damage.

I would see a urologist, though this doesn't sound like PD to me. MG

I am a clinical social worker treating a patient with this condition. He is scheduled for surgery and understandably has anxiety. What are the satisfactory results of surgery? Is there anyone out there who can e-mail me about their satisfaction Are there any negatives to surgery and why is it a "last resort?" What are the other options?

For disabling defornity that has not responded to medication, there really are none. Regarding satisfaction, I'll put this out to the readers. MG

I would like some information and specific instructions on mixing, using, and applying the thacker formula.

I have no idea of what this is. Does anyone out there know? MG

After a successful hair transplant 3 years ago I was advised to take 'Avodart' to reduce testosterone, a cause of male baldness.Hair density improved considerably and life was good. A side effect was a reduced libido, and consequent reduction in erection size, strength, and ejaculation. I also noticed the now distinctive upward bend and assumed it to be the Avodart. I stopped taking the drug, hoping for my penis to gradually return to his former glory. However the condition is worsening and the upward bend is continuing to be more pronounced. I only found your site tonight by chance and now realise I am a classic P.D. case with all the symptoms. My point is that in my opinion the Avodart caused the softer penis to be damaged during intercourse and this trauma brought on the P.D.

This was proposed by a Dr. Hinman many years ago: PD comes on in the 50's when erections are not as hard, thereby causing damage to the penis. MG

 

February 2010

it stands to reason that some massage therapy will help with the curvature issue, by gently bending backward to stretch the plaque and loosen it. What do you think?

Controlled non traumatic stretching may be of benefit. MG

I had robotic radical prostatectomy in Sept 08 (spared all nerves) and have developed Peyronies...slight curvature..never had this before. No erection problems before or subsequent to say 3 months after surgery. Urologist put me on 400 IU daily of Vit E six months ago. Am on Crestor and Niaspan for preventive cardio with baby aspirin and fish oil daily. Sometimes it is worse than others but sex is becoming problem..no orgasms with penetration and my partner since my surgery and last nite she was in pain from my curving, which was worse than time before. Severity varies in terms of how much curving.

PD is more common in men who have had radical prostatectomy. MG

I'm 31 years old and for as long as i can remember i have had a bent penis on erection, a 20-30 degree angle to the left. I dont remember ever having any painful erections. I have a good length (never measured it but i imagine close to 8") on erection, i have spontneous normal erections and preserved libido, i can get stone hard erections but the glans never gets hard and i dont enjoy the sexual act the way i'm supposed to, i have always had delayed ejaculation when with a partner but can come easily when masturbating alone. Also I have always had trouble sustaining erections and started meds (viagra, cialis..) which have worked charms the first year but now that i'm engaged in a more stable relationship and that i use them more often i feel these meds fail me 1/3 of the time. I'm healthy in all other aspects, dont take any meds and exercise regularly, i also quit smoking with success 1 month ago in the hope that cessation will improve my ED, i feel great but the problem persists. -Is my curvature secondary to PD or congenital? And is it contributing in any way to my ED?

I think the curvature is not PD but congenital, and is probably not contributing to ED. MG

Are there any physical devices that work or are they all jus junk?

We really don't have a good answer - some have benefitted from stretching while others have just ended up with a sore penis. MG

I've some curvature in penis when it erects and some softness in the base point. What is the cause of this and is there any treatment for this diseases? Please give me pefect advice.

Best advice is to see a urologist at this point. MG

MG I am a female with a husband with this..For 15 years.We are 61 now? I didn't want him to have surgery for me, so he could feel without surgery...I would not want that on anyone Sorry,I try because,I love him. Is there a new surgery now?

The state of the art as regards PD surgery has improved over the last 15 years. MG

 

January 2010

I'm a 25 yr old male and have had a left-curvature for about 5-7 yrs. I believe it happened after I started having sex (I had fairly aggressive sex), but cannot remember if it existed prior to this. The curve exists when my penis is soft or hard...and I am not getting hard as much or as long as I used to. Can this be a psychological thing? Or is it because I have developed ED? Or both? This problem has affected my relationship with women as I am somewhat embarrassed to show them my penis. I have seen a urologist and he wasn't too helpful. I do NOT have any pain while having sex. But in the middle of the night I tend to get powerful erections which I make an effort to straighten with my hand. Will trying to straighten an erect/curved penis cause more scar tissue? Do you beleive this is Congenital Disorder or PD? And since I do get really hard during sleep, does this rule out ED?

This sounds more like congenital curvature, which not infrequently will cause embarrassment or other self-image issues. You will not correct this by trying to force the curve into straight configuration. MG

I was diagnosed with PD in October. My penis is bent up and to the left perhaps 45 degrees when erect. I saw a Urologist in early November. He prescribed verapamil 15% twice a day, told me to check back in 6 months. On my own, I am taking 1000iu of Vitamin E. I see no change so far. I use Viagra 50mg. for the ED. I have some burning pain with erections. Should I just wait it out for 6 months? Would daily low dose Cialis help? I'm taking the Viagra about once a week now. Would one of the penis stretchers like Andropenis really help? I hate to just sit back and wait, only to discover that 'uh oh, its too late to fix it'. On the other hand, the stretcher isn't cheap, nor would be daily Cialis.

There may be a theoretical advantage to using Cialis or Viagra, but as there is no controlled data proving their benefit, they would have to be considered equivalent. The evidence for stretcher benefits is also somewhat thin, and if cost is an issue I would pass on that. MG

I am a 33 yr old male. Back in August of 09' I foolishly used a penis extender hoping it would add some length on to my member. I only used it a few times, but must of over stretched my penis. Afterwards my penis was left somewhat desensitized & tingly. I went to see a urologist who examined me and told me that I probably bruised/stretched some nerves, but that he thought I would be okay. about 3 weeks ago I noticed a smooth lump on the right side mid-way down the shaft of my penis. I currently have no bend or pain in my erections--but I am worried that this might be the start of Peyronie's. I plan on seeing my urologist next week, but was wondering if you thought this was just some scar tissue left over from my injury or the start of something worse?

Does not sound like PD - will probably go away. MG

In November 2009 I went to the urologist for having to pee alot and at night and to get a prostrate exam which was ok. He gave me some medications to try and they helped a little but generally didn't work. He wanted to determine bladder volume content and suggested some tests. A catheter was inserted on 2 ocassions,once with a scope. I was not having any penile curvature problems before this. Some ED, but No curves. In December I thought I must be crazy, cause I thought I was shrinking. Now it is January and I am having an upward curve upon erection along with the shrinking. What action should I take? I don't know if I want to go back to this doctor, although he was supposed to be competant. Why did this happen?

Peyronies Disease may follow catheterization or instrumentation of the urethra, though this is a very uncommon complication. MG

I have had peyronie's disease for 8 years. I had received care from these doctors: Tom Lue, MD - UCSF Kessler, Robert - Stanford Jacob Rajfer, MD - UCLA I'm writing to find the best doctor in the world. Who is the most recognized doctor for treating Peyronie's Disease?

I guess I can't nominate myself...those are all good doctors for PD. MG

I am thanking you in advance for your public service of donation of your valuable time. I am a 47 year old white male serving in Iraq. About 6 months ago during masturbation I thought I noticed a "dent" in the right hand side shaft of my penis. I dismissed it as my imagination. Two weeks ago I started to have pain in the penis during nocturnal erections. I became concerned and really gave a good inspection to my erect penis. I do believe there is a dent on one side The nightly erection pain has gone away 2 weeks later but not the dent. I have absolutely no nodules or plaque that is detectable. I have spent several hours now trying to detect lumps or plaque but I can not. When I have a very hard erection I do seem to get some form of pain though. I can recall no injury to the penis. Does this sound like PD without the plaque? Thank you Doctor, it is not possible where I am to see a physician.

Tthis sounds like a mild form of Peyronies. when associated with indentation only, without siginificant curvature or plaque, it usually resolves spontaneously over 6 -10 months. My only reccommendation at this time would be to get on vitamin E 400 units daily. MG

I am 60 years old. Although it may have been emerging earlier, I was first diagnosed with peyronie's 10 years ago. The diagnosis followed my noticing internal plaque-like hardness at the base of my penis. Gradually that seems to have become less noticeable, but over the last year or so, my erections point to the right at something like a 45-degree angle. During intercourse (and the need to straighten my erection) I am aware that my penis withdraws almost as if the tightness causing the 45-degree angle continues to bind in such a way that as my penis is straightening it pulls the erection back resulting in a considerably shortened erection. Recent conversations with my primary care doctor and a new urologist didn't provide me with any useful information. I wasn't convinced that they were familiar with peyronie's diagnosis or treatment. I am not using any ED medication. Is it possible that this symptom would change if I did start doing so.

PD itself can cause shortening, though you may have less of this curvature-related effect with the use of E.D drugs. MG

I'm 51 and have had Peyronie's disease for about 4 years. I believe mine was caused by trauma. I have the same symptoms as most on this board. No pain. Sex is fine, but would obviously like to be back to normal! We've all read the herbal remedy stuff on the net. Is there anything to any of the products? They all look the same (hokey) to me.

Unfortunately I think you're right; there is no great evidence that these herbal products work. Interestingly, the new drug that Auxilium Inc. is developing for PD (Xiaflex) is a "natural product", as it is a naturally occurring enzyme produced by bacteria. MG

I have recently discovered a tiny pebble-like nodule at the top of a thin firm vein-like structure on the top right of the corpora cavenosa. It appears to be just below the skin. There is no pain/discomfort or signs of bending. PD?

This sounds more like Mondors syndrome, which is localized clotting in superficial veins. It is innocuous and self-limited. MG

My pd and my wife's lower libido have really done a number on my penis. i'm wondering if our now infrequent and less fulfilling lovemaking is exacerbating my pd. is there anything short of surgery (poor choice of wording) i can try, like a medical pump, or do i just have to deal with it? it's surprising to me that there hasn't been more successful research on "curing" peyronies "disease" considering the quality-of-life issues involved.

Many people share your frustration with the lack of productive research on this issue. There are reported successes with the use of vacuum pump, though there are no medications that the FDA has deemed "effective" in the treatment of PD. MG

I then was diagnosed with PD, and put on Tamoxifen and Vitamin E (800, then 1000mu). Between October 2009 and early December the condition weekly got worse and my Penis became more upwardly bent on erection, and it was painful to have an erection. Seeking alternatives, my Doctor put me on Homeopathic medicine, and I have been taking Thuja (Once daily), Thisomanum (twice daily) and Sulphur 30 (twice daily, once a week). I am glad to say that since the 3rd week of December, I now have no pain at all on erection and the curvature upward has stopped at about 20 degrees. I am completing the course of Tamoxifen and Vitamin E though through my own choice, which was agreed by my Urologist who recommended now to stop, and if it stays like this and doesn't progress I will be happy to live with it as is. Can PD come back at a later stage in life or if you have had it once is that it? I am currently 36.

PD usually runs its course in 18 months or so, and is unlikely to return. MG

I am 56 and have all the symptoms you list. Hard flat spot under top flesh of penis. Shorting of penis Bend to the left Pain during erection. Slight burn upon start of urination. I have a fairly constant dull aching pain when even just sitting. Rubbing of penis against loose underwear aggravates this pain as well. This pain is not intolerable just there. Is this PD. Should I start with my family doctor or go directly to an Urologist?

It sounds suspicious - I would recommend a urologist. MG

My son who is 19 was prescribed 400 mg of Pentoxifylline 3 times a day for his PD. Comments on such a prescribtion?

This drug improves blood flow and has been used for PD. It is relatively safe, though there is no controlled data proving its effectiveness. MG

I recently had a very successful needle aponevrotomy for Dupuytren's with Dr. Charles Eaton. http://www.handcenter.org/ Like may DD patients, I have PD. I know that you were initially skeptical, at least as a gut reaction, of the Leriche Technique, but it and needle aponevrotomy seem to be based on a similar concept. Any further thoughts?

Unlike the palmar anatomy, critical neurovascular structure are too close for comfort in the penis. Using a needle to cut a penile plaque can injure the nerves immediately above it and cause numbness of the head of the penis. MG

About eight months ago, I overdosed on Viagra (200mgs). The next morning I had an erection that didn't subside completely, but still was only half erect. It was not painful, and I was concerned, but didn't seek help because I didn't think of it as a priapsim. It lasted about 12 hours and subsided. The next day, I was sore. My urologist said that it was not a priapism if I had even a little flaccidity during the erection. Since it was up and down all day, he ruled it out, and said my corpora were sore. He said the pain would fade in a week, and so it did. About two months later, the pain resumed, and I have had it for about 6 months. Urologists tell me that the trauma of a priapism is not the same sort of trauma that is known to cause PD, and that priapisms don't cause PD nor does viagra overdose. I have also noticed that there is a slight hourglassing an inch below my glans, but it is gone when I'm 50-100% erect. It hasn't gotten worse that I can tell. My questions are: Can priapism/viagra overdose cause PD? Is a slight hourglassing that is visible when only a quarter erect a symptom of early PD?

I don't think this is PD, and hourglass of semi erections is not a symptom of early PD. MG

I am 63 years old and developed PD 2-3 years agoWith Cialis I can get an erection adequate for intercourse but often lose it during intercourse (but not always). I tried a penile constriction ring which allows me to maintain the erection better, although I have not tried it with intercourse yet (I am concerned about ejaculation with the ring on). I believe my pathology may be a venous leak due to the PD. Do you agree with my diagnosis for the ED or should I have additional testing? Does ED due to venous leak caused by PD ever improve with improvement of the PD?

I agree with your diagnosis and although venous leakage due to PD may improve with resolution of the Peyronies, at 2 - 3 years duration I doubt this will happen. MG

 

December 2009

I am 60 years old and in good physical condition.I take no prescribed medications and am very active overall. About 3 weeks ago I noticed that the end of my penis had suddeny deveoped a bend upwards. No pain, just a 20 degreee angle about one inch from the tip. I went to see a urologist and he said take 400mg E twice daily and an anti-inflamatory (I take Advil twice a day) and to come back in 6 months. He also examined my penis and said that I had cassic Peronies thickening around the tip. I had no trauma to this area and I am quite sexually active. MY Penis still works ok but I am very motivated to address this issue especially as I hear that in the early stages treatment may be more effective. The doc says he coud not detect calcification as this time. I have been reading the forum and can see there are many medications and treatment options floating around out there withour much clinical evidence to prove effectiveness. My question is what can I do NOW to minimize the chances of it getting worse and hopefully restore myself to my former shape ?

Keeping sexually active without traumatizing the penis will help, and the following supplements have their adherents (though you are correct in stating that hard clinical evidence is lacking): L - Argenine 1000 mg twice daily, acetyl - L - carnetine 500 mg twice daily. MG

I am 42 years old. I began to notice painful erections about 5 months ago. I went to the urologist after 3 months of noticing the pain and also noticing a hard spot on the base of my penis. When erect, my penis curves sharply to the right. There spot in my penis seems to have a hard, thick side and a smaller thin side. The urologist started me on colchicine. I have also been taking vitamin e. I am supposed to follow up with my urologist in 3 months. He told me that he maydo an interferon injection. I have been taking the cochicine and vitamin e for over a month. I have not noticed any real improvement. I have read about neprinol being used for PD. Would that be wise to take the neprinol as well as the colchicine? Also, should I attempt to persueade my urologist to start the interferon injections sooner.

Neprinol has helped some patients, though there is no formal clinical trial - based evidence that it works. Many authorities believe that starting medical therapy (i.e. interferon) early is beneficial. MG

I am a 45 year old male. Six months ago I was diagnosed with Peyronie's Disease. I rarely have pain and I have a noticable band around my penis about 1.5 inches below the head which is getting worse. I also have a slight bend backwards. I am taking Vit E however this does not seem to be working. I just read an article on Neprinol stating that this enzyme digests scar tissue associated with PD? Does this really work and should I speak to my doctor about this?

See the response above - the problem is, we don't really know if it works. MG

I am a nurse and spoke to a Urology Resident about my husband's symptoms (curved penis) a couple of months ago and based on what I told him he said it sounded like PD. Unfortunately I didn't start researching the disease until 2 days ago and now I am worried that since we took so long to do anything (he has had the curve for several months) that permanent damage may have occurred. The last time we had sex (a week ago) he was unable to stay in me due to shrinkage. It also seemed to me that it is becoming harder for him to achieve an orgasm, something that has never been a problem in the past. He says he has no pain and has never had any pain with erections. He also says that he doesn't feel any lumps. Is there any other problem that could be occurring?

Waiting a few months will not have caused any damage, and this sounds like PD. I do not believe there is any other problem occurring. MG

I'm 20, and when erect my penis bends slightly downwards no more than 30 degrees. My penis also narrows very slightly towards the middle. I've had this since I could remember, and my penis head does not "pop out" of its foreskin like most guys when erect. There's no pain or anything and I can have sex fine. But it's an aesthetic eyesore, I was wondering if you could tell me what condition I might have and what treatment is possible.

This is congenital curvature, which can be corrected very effectively with the Nesbit procedure. MG

Over last 5 years or so, my penis has developed an upward curvature, loss in length and loss in diameter but no pain. It's really quite embarassing and I have subsequently lost much interest in sex.I and my wife really would like to have a sex life but the "little feller" just isn't up to it. I feel like a grown man with a boy's penis. I saw a urologist but all he had to offer were drugs for ED which gave me quite a headache and didn't do anything for length or girth.

Loss of interest can occur in PD, due in part to embarrassment and loss of performance. Unfortunately the loss of length and girth in this disorder may not be reversible. MG

I went to the dr after a few months of painfull intercourse. I was scared that I had an STD. Turns out that I had PD. I have had PD for about 6 months now and sex is still extremely painfull. My uroligist said that he couldn't do anything about the pain or the PD for about a year. The bend is right below the base and I now have about a 90 degree bend when I get an erection. The dr said that it would be a risky surgery and may leave me impotent. I obviously don't want that. The real problem is my wife. We used to have great and wild sex and I know how much she enjoys that kind of sex. I try and find reasons to not go to bed when she does so I don't have to perform. She is very supportive and I know that she knows that it hurts when we have sex but I know that she is not as satisfied as she used to be. Is there anything that will help with the pain or is there a way that I can get back to my "old form" without as much pain.

I would recommend taking ibuprofen an hour before sex. Fortunately, the pain of PD will eventually resolve on its own, though this usually takes more than 6 months. If the severe bend persists for more than a year you may want to consider surgery - by someone with experience in this particular problem. MG

I had corrective surgery in June of 2008. I have noticed a decreased sensation and have trouble maintaining an erection. Although Viagra helps with the erection it does nothing for the sensation. Is there any treatment to help?

Sensation may be temporarily reduced after surgery, and B complex vitamins may help it to recover. Since a year and a half has passed since your procedure, it seems unlikely for further recovery of sensation to occur, though in some cases nerve recovery can take well over a year. MG

 

 

November 2009

 

I have a hernia located in my groin area and I also have a mild case of peyronies. I have two questions: 1.) Is there a chance that the scar tissue that my body creates as a result of the surgery repair will spillover into my penis? 2) If I do not have the hernia repaired will my brain keep sending messages to body to create scar tissue in this area of the herniation and than this may also cause the creation of scar tissue in my penis?

These two conditions are unlikely to affect each other. MG

I was diagnosed with peyronies over a year ago and the condition is now stable. I am 59 and up until then had a healthy sex life but now my penis has shortened by 2 inches with an upward bend of at least 35 degrees plus I have indentations (hour glass) either side but not opposite each other. This causes my erection to be narrow and painful at times. My wife has noticed a considerable loss of satisfaction during love making due to the shortening and bend in my penis. Do you know anything about the Penile Dermal Flap (Krishnamurti) Operation for Peyronie's Disease and is it different to the tissue graft method and more effective?

This method uses a tissue flap and has certain advantages, though it cannot be done in a circumcised man. Unfortunately no operation for PD will restore lost length; they will only help to correct the deformity. MG

Is there any evidence that taking "Cialis Daily 2.5mg" caplets over time has any effect in the treatment of PD? The low dosage appears to have helped me return to normal daily sexual cycles while nearly completely eliminating side effects of other higher dosage ED drugs.

To date there is no controlled clinical trial evidence, but many specialists are recommending it as in addition to the improvement in erections, it may play a role in counteracting scarring. MG

I'm a 55-year old male who has been on lifetime anticoagulation therapy for three years (artificial aortic valve). Two months ago I had a significant retroperitoneal bleeding episode that also caused severe bruising of my groin, scrotum, and about 2/3 of the length of my penis. Coincident with this occurrence, I now suddenly have two indentations, a moderate upward curve, and an ache when erect. Does this sound like true PD to you or is it something different? Do you think that its' onset was caused by the retroperitoneal bleeding or is it just coincidence? Generally, is PD associated with anticoagulation therapy?

This does sound like PD, due to the hemmorhage. Anticoagulants are not associated with PD. MG

I started to develop a slight bending of the penis about 6 years ago, but it has gone more pronounced over the last year. I'm now 55, which seems to fit PD from what I've been reading. It is not painful in intercourse. It just looks a little strange. I had a vasectomy procedure in 1987 that involved cauterizing the vasal ends (I believe this is what was done). Could this procedure develop scar tissue that leads to PD?

There is no evidence to suggest this. MG

What is your expectation regarding the outcome of the Xiaflex collagenase trials based on your prior studies? Do you think its worth putting off a Nesbit proceedure in hopes that collagenase will prove effective? When Xiaflex is approved for Dupuytren's, as it likely will be, do you anticipate that it will be used off label for Peronie's before it is offically approved? Is that reasonable now before the trial? Would it be reasonable if the trials are sucessful but before actual approval???

The phase II studies of Xiaflex in PD were encouraging, and phase III studies are in the planning stage. Even if all goes well, it will be several years before this drug is approved for the treatment of PD. Whether xiaflex will be used off label for PD depends on mediolegal concerns of the treating doctor, experience, and the consent of the patient. MG

I just noticed in the last few weeks that when I have an erection, that my penis, just behind the head, bends left a few degrees. When it's flaccid it looks totally fine. No knots, bumps or dips in the shaft. It did look like it had a bruise at the bend. What's going on? It's like the skin is tighter on the left side causing the head to bend to the left.

This could be PD, or just a temporary inflammatory state. The lack of bumps or nodularity is reassuring. MG

Went to see a local mens clinic who prescribed penile injections I used it about 6 times but no dramatic improvements. I noticed about a onthe or two ago that my penis has developed a fairly sharp curve {about 20 degrees] to the left. Not painful, not rigid but can the injections be a cause of this. I never had any problem like this before. My testosterone levels are also very low 3.9 to be exact and have seen a urologist who prescribed sustanon injections for 6 months. Ive had the injections before but it did not seem to help. Looks like something shut down somewhere!

Local injections can cause scarring that leads to PD. MG

I am currently 48 and I started feeling the onset of peyronies symptoms in the summer of 2008. My penis began to get so painfully hard I thought it would explode. Sitting in the hottub only made it harder and more painful. My penis was well over seven inches long, and also had a very nice circumfrence to it. By the winter of 2008, it had began to take on the hour glass shape on the left side and orgasms were very painful all the while slowly shrinking. One day I woke up to a 4 1/2 penis that was half of what it use to be in girth. I am certain my sex life played a key role in this happening because I use to have some really rough sex that would last for hours at a time. Yes, I really liked sex and would go for hours. Alot of the time my partner would be on top and when she would move a certain way my penis would sometimes get bent hard and fast and man was it painful. I am sure scar tissue built up as time went on. It has been over a year now and i am on the down-side of it and can see some natural healing and improvement but nothing worthy of calling a break-through. I experience erections all throughout the day and wake up to them all the time. I tried different kinds of vitamin E creames but found that masturbation works better than anything else to help keep it stretched. I am looking and praying everyday for a cure to be found so I can get my original penis back. I want to get back to it like I use to.

Rough sex, particularly with partner on top, can cause the type of injuries that lead to PD. MG

I read a FDA report about Jes-Extender and X4Labs where it is commented that this device is not allowed to be imported and distributed in the USA. My question is..how is it possible that some known doctors such as Dr. Levine and Dr. Giunta are selling these prohibited devices currently? what are the risks of using these not approved devices?

I am not sure about this, but I think Dr. Levine was studying the Fastsize extender. Another device used in this country is the Andropenis extender. The jury is still out as to whether these help PD, but are probably not harmful if not used to excess. MG

I launched a peyronie's disease website a few months ago, in part due to my own need to communicate about the disorder, and also since there is a disappointing lack of peyronie's disease sites out there. I'm emailing to ask if peyronies.org would like to exchange links with the site (http://www.peyronies-disease.co.uk). Your link has been added to the link page, and I will be limiting the number of type of sites I link to

Thank you for the links. MG

I have had a downward bent penis for a year. It does not hurt and has no discomfort. But it hurts my wife. Do you think this is peyronies?

If it has only been present for a year and you were previously normal, yes. MG

I am a 57 year old male an have self diagnosed myself with Peyronies disease. I have the classic symptoms. my penis is starting to curve up and seems to change almost daily. I had be taking glucosamine and condroitin which I stopped after reading your forum. I will be seeing my doctor soon. I have started taking 400 mg vitamin E. Do you know any other treatment such as Peyreton to be effective?

There is no clinical trial - based evidence that Peyreton is effective. MG

 

October 2009

 

Many sites state like you have that "correction of curvature that has been present and stable for more than a year or two is very unlikely ". If this is the case, then what can be done in the first few weeks or months to prevent the plaque from forming or to prevent things getting worse?

Medical treatments (verapamil, interferon, colchicine, pentox, vitamin e, neprinol, l-argenine etc.) are all given with this intent, though data demonstrating their effectiveness is thin. MG

I have suffered from Peyronie's disease for 10 years (I'm only 35 years old). I also run a website development company in the UK and I had an idea for a web based project to investigate the disease. Indeed I hope to include other diseases that have been neglected by the research community as well. My idea is that over a 12 month period I will collect theories into the causes and treatments for Peyronie's, I will test those theories anonymously with a questionnaire and then I will visualise the data in lots of innovative ways. Hopefully we will find epidemiological patterns in the data which will provide as a catalyst for further research. The project can be found at www.healthpatterns.org and the website includes much more information about the project and the opportunity to participate anonymously.

Thanks, I'll post your message. MG

I have a slight bend in my penis that goes to the right but can straightens out when I pull it a certain way, which i have to do during intercourse. Regardless of the curve I have been having regular sexual intercourse without any problems, but feel recently that the curve has gotten worse, which could be all in my head. My main question is are there any effects or things to be worried about when taking products such as Extenze and a curved penis? I have recently ordered a supply of Extenze natural male enhancement products and have seen in some places that the increased blood flow may help PD and cause it to straighten a bit bc the increase blood and expansion of the veins allow it to straighten. Is this true? Can male enhancement pills help to straighten a curved penis? Or could it even have a reverse effect and bend more because of the increased bloodflow?

Male enhancement products will not straighten a curved penis. You should be aware that there is no good controlled scientific data showing any of these products "increase blood flow." MG

Hi. I'm a 26 year old. And I've had a "bent penis" at least since I was about 13. I might have had it for longer, but I never noticed. Then again, maybe I didn't have it. I don't remember any pain at any point in my life in that area. But my penis has a downward curve of almost a full 90 degrees. It looks like Gonzo's nose from the Muppets. It seems like over time my penis length has gone down too. I distinctly remember measuring when I was in middle school and reaching a full 7.5" in length from base to tip. But it has shrunk at least an inch since then. I can bend it straight with my hands with enough force, but to maintain it like that after a time, it begins to hurt. I am not sexually active, but will this be a huge problem when I do become active? The erection itself doesn't hurt at all though. It only hurts if I try to straighten it too much. Anyway... are there any options besides surgery? I don't want to have my already shrunken penis get even smaller, and I don't want to have to take erectile medication at my age.

You have congenital curvature. With a 90 degree downward bend, you can expect some difficulty when you become sexually active. Unfortunately, the only way to correct this is with a Nesbit procedure (surgery). MG

hi im pete im 24yrs old and i have a bent penis that ive had all my life, born with it. i doubt that i have peyronies disease because i got no penis pains and there is no hard lumps or scars. i saw a uroligst and he didnt say whether or not i have peyronies but he ended up doing a nesbitt procedure on me. i had a severe bend (if 180 degrees is straight, then my penis was 90 degrees, a complete L shape) Now after the surgery which i had about 3 years the bend is less, about 140 degrees but im still not happy. i still find it hard to have sex with women and my girlfriend complains that the bend huts her while having sex. I need to know if there is anything i can do to straighten it a bit more and i dont want another surgery because i think that will cause complications. Would pumps work? i own a straightening device that lengthens it over time but i dont know if it would work, id have to wear it 9-10 hours a day for 6 months. also would peyreton work for me, its some pill witha guarantee, at peyreton.com. also i heard if i suppliment having primrose oil capsules it has an ingredient that makes the penis more elastistic so that might help. Anyway could you tell me what my options are, and what you think and please give me some feedback as in dont tell me it is normal and to live with it because i cant.

Medications don't work for congenital curvature. You do not have Peyronies disease. If the surgery was done by someone who didn't completely correct the curve I would recommend you see a reconstructive urologist with experience in this area, as a minor revision (by someone who does a lot of this work) is your only real option. MG

I am 65 years old man and I noticed the first symptoms of PD 16 months ego. There have been several stages of deformations, mostly the first three four months and a very considerable shrinkage but I believe that it has stabilized now. There is an upward bent of almost 35 degrees making it almost impossible to have intercourse but the worrying part is the lack of erection probably on account of my psychological state. My question is, during the last 16 months I had never had any pain or even discomfort at all and I cannot detect any lumps or any kind of thrombosis on my penis. Could you explain it or recommend anything

I would recommend you see a urologist to start on some type of medical therapy as well as a phospodiesterase inhibitor (viagra, levitra, or cialis). MG

About two months ago during masturbation I noticed an instant change in my penis. A vein that goes from base on the top-side of my shaft and wraps around has become swollen. It's very prominent even when flaccid.. especially after erections.. Since then I have noticed that when an erection is going down the head of my penis becomes smaller and goes off a bit to the left while the base area seems larger (almost like an arrow). Full erections seem normal, but when they go down it feels like everything is out of place and many veins become swollen. The Corpus Cavernosum of the penis is also very solid when flaccid (certain areas moreso than others). This usually occurs after an erection, but sometimes it happens without one. Sometimes just sitting a certain way can cause it to flare up. There is a lot of pain that comes and goes. (throbbing and burning sensations). It's an awful pain that travels throughout the entire penis and is almost unbearable. (Note: I have been tested for STD's and blood clots). I spoke to a doctor and he told me I have Peyronies. I have been taking Vitamin E and Ibuprofen for the past week.

That may the case, though this is somewhat unusual - Peyronies does not cause veins to become swollen. MG

I am 69 and diagnosed with Peyronies disease five years ago. It has been stable for the last three years. While I have more than one "spot" the major problem is a 70 to 90 degree upward bend about a third of the way from the penis tip. I have lost length and some girth. Mayo Clinic has strongly advised a Nesbit procedure. My wife and I are sexually active and only one position works at this time. I am apprehensive about having surgery as we are "getting by" and my wife is ok as is. What is the technical success rate for a Nesbit procedure and what is the general psychololgical satisfaction level from a Nesbit?

The rate which we see erectile dysfunction after a nesbit is less than 3 or 4%, though some patients will be unhappy with the length loss if they were functioning well prior to surgery. The procedure is very likely to fix the curve, but with a 90 degree bend you can expect an inch or more of length loss. MG

i went to urologist 1 yr ago , where i suffer from penile curvature down with 45 degree, he told that my case is pyronee disease and ask me to get potaba .5gm as a medecine but i couldnt get this medecine here in jordan or in dubai ' i am working in dubai ' in order to get this medecine i went to another docor in dubai but he said my case is chardee and i need a surgery for correction. now i am in vacation in jordan , i went back to my first doctor , he insist that my case is pyronee not chardee, and he insist to get potaba and he warned me from the surgery, my case is , 45 degree downward curvature during erection , which cause failure in sex process that preven me from penetraion , i dont remember when this start with me but i remember it is from many years , i am now 33 yrs old , suffering this many yrs go....

Considering the long time you've had this problem and the downward bend, I'd guess this is not Peyronies but congenital curvature - which requires surgery. MG

I am 60 have had PD for 9 months now. My urologist suggested the veperamil cream and vitamin E and I have seen no results. I have a 90' bend with hour glass shape at the bend. At the last visit he asked if I was ready for surgery, an implant. I declilned as I know there are other more suitable operations available. Are the injections worth persuing? Is there anythingthat helps at all?

Implant surgery is good if you have no erection - if you do, a reconstructive procedure with grafting is a better option, provided it is done by someone with experience. It can correct the curve and allow you to retain your own natural erection. MG

I my concern is with my penis and if i might have PD. In 2005, i noticed the penis appears to be narrower in the middle of the shaft when limp.Sometimes when limp it is very hard and short. When erect, there is indentation at these narrow parts (left and right of the shaft). No pain or discomfort. The indentation is about 2mm wide and 2mm deep as felt by hand. Also, at one of the indentation there is a painless bead (calcium deposit?). My question is, if it is PD, is it already in passive stage, or will it continue progressing?

This sounds like PD, which at this time would be expected to be in the stable passive phase. MG

 

September 2009

 

My penis bends to left and sometime it can be seen from pant, which looks wiered and bad in front of others. Even the shape of the pants from front side looks different from others, when I walk on the road people look at my front side of the pant which looks diffrent for them from others. Can u plz tell me how can i rectify this problem so that i can also have same shape of my pant like others and my penis doesnt seen from the left.

I don't think you have Peyronies disease. MG

My boyfriend is 24 and was diagnosed. It has been a little bit over three months. The pain has started subsiding but the plaque is still there. He has tried aggressively to get treatment but when his family doctor sent him to a urologist he said he needed to wait. He went back to the family doctor to ask for a second recommendation where the doctor refused and sent him back to the same urologist. He went on Monday, and was told the same thing to wait…. I keep reading that you need to take care of this in its early stages but as you see that is not what is suggested. The only thing the urologist prescribed was Viagra, which by the way did not do anything. Please help!

You are correct in stating medications seem to work better earlier in the process. A more aggressive approach at this time would be to start on colchicine and vitamin E orally, as well as a series of intra plaque injections with verapamil. MG

Good day, I am glad to share my experience with this disease (Peyronie's). I am fastly approaching 55yrs and I cannot remember experiencing any trauma in that area, On the morning of 2nd August 2009, I went to the bath room and after urinating I felt a sharp pain and saw three (3) swollen lumps on the top vain of my penis, the pain became worst as the days progress. I visited my PD and he recommended me to an Urologist (21/8/2009) who identify the problem and started me on Vit. E (1000). Presently I am without pain and the sollowen bumps on my penis vain have all subside. I have an appointment with my Urologist in two (2) weeks time. Apart from using the Vit. E, I also munch on a few pieces of aloes and also use a hot rag on the area and use Dolobene Gel. I hope my testimony will assist in someway.

Thank you. MG

I am a 19 year old man who has undergone the nesbit operation. I read on the internet that you shouldn`t mastrubate until 6 weeks after the operation, but i also read that you could mastrubate by pulling only the foreskin and not using the whole hand 2 weeks after the operation. so I mastrubated in this manner. I was very careful and only used my fingers pulling the foreskin and never with my whole hand. My penis is now almost straight and sometimes I have some mild pain in my flaccid penis after mastrubation but it goes away fast. I am wondering if my penis could have been even straighter and that my scar could be looking better, and that I would have no pain if I didn`t do it?, and I can`t stop thinking about it. I had a bend between 20-25 degrees downwards a little under the penis head so my penis kind of had a hook shape. I also have an houglassshape in the middle of my penis that comes along when I am semirect but goes away when I become erect, when it appears the skin is a little darker around the area.my penis also lean a little to the left when erect starting from around the area where the hourglassshape appears when semierect. Could this be peyronies? I am also wondering if the stings in my penis will most likely hold my whole life or not.

This is congenital curvature, not Peyronies. The discomfort will resolve and the cosmetic effect will improve over time. It takes several months. MG

I am 45 years of age. 2 months ago, I started to notice that intercourse was starting to become a bit painful but very slight initially (I have sex about once a week). Each week I noticed it would gradually get worse until last week, the pain was at a point where I had to stop (This pain came quite abruptly considering the prior week the pain was still somewhat slight). After doing a self-examine, I noticed a small pea size lump deep inside my penis about 1 inch from the base, right side. I went to a Urologist the next day and he diagnosed my situation as PD. He recommended a series of verapamil injections saying that he has had very good success with his patients. I currently do not have any curvature of the penis. Does the Pea size knot sound like a typical symptom and proper diagnosis?Should I wait before doing any injections and see if the problem will resolve itself?Should I refrain from sex (will this worsen the situation)?

This sounds like Peyronies to me. Verapamil works best when used early in the course of the disease. There is no reason to avoid sex, if you're not too wild.MG

I am 47 years old. Diabetic for 22 years now. I was diagnosed with PEYRONIES 2 years ago. I started to feel the pain during erection recently and the intercourse is more difficult nowadays. Shortening of the penis is really bothering me. What is your advice? If surgery can help, please direct me to the best doctor in the US.

Unfortunately, surgery cannot correct the shortening caused by PD. MG

I am a mid-20's otherwise healthy male presenting with 42degree to the left. I am hoping to undergo the Nesbit procedure in 3-6 weeks. Before this takes place I will have a final assessment with my urologist. After a brief initial discussion his feeling was toward the Nesbit procedure with non-absorabable sutres. Information on sutre types regarding specific procedures seems to be thin on the ground - I suspect I would have to be subscribed to various Journals to obtain the information. I'm slightly confused as to the preference for non-absorbable sutres and how post-operative curvature recurrence actually occurs - how does this happen when the excess length has been excised in one or more ellipses? As a non-medic in my mind the lengths are now 'equal' and the sutres are merely holding the newly-exposed surfaces together while they heal. I see the removal of excess on the longer (right) side to be a permanent, immediate redress and cannot fathom how curvature can recur, leading me onto the issue of sutres; is it the postoperative scarring/healing between the newly exposed surfaces as a result of removing an ellipse(s) that ultimately yields the strength to 'hold the whole thing together'?

Experience has shown that the use of absorbable suture in the nesbit procedure can be associated with stretching of the ellipse site and (partial) return of curvature. I recommend a 2 layer closure, using a few interrupted non absorbable sutures under a running line of absorbable material. MG

Hi, I'm a 45 years old and have had PD for about 1-year with lumps are close to the left base of my penis. The web-site is very helpful but doesn't have information about stretching techiques, which I have heard helps. Do you think its worth trying and what techniques would you suggest?

Some have reported improvement using the fastsize or andropenis stretchers, which are available on the internet. The Augusta company makes a vacuum device with graduated cylinders that accomplish a similar effect. MG

I was just diagnosed with PD. I don't have much bend, my penis is just about 1 inch shorter and the head and upper shaft don't get firm. The Plaque is located in the lower part of the shaft. Would ED meds help firm the top half of my penis?

Yes they will, and there is some evidence that these medications help to reduce scarring as well. MG

hi i had sex and in middle of sex heard a pop sound no pain or swelling after but now 3 weeks later have seen a darkening to the middle of my penis and it seems longer and thinner when flacid and when getting hard goes thin in the middle like a waist band then when fully erect is normal again what can i do is stressing me out and am worried

Give it some time, this will probably resolve. I does not sound like PD. MG

I am a 62 y/o male; had an MI in 2/09 w/x4 stents. Thereafter I started metoprolol 25mg BID. In the past few months I have noticed my penis is acquiring a decided bent shape on erection. It is not painful, just not fully erecting to its normal fullness and decidedly bent; making it increasingly awkward sexually. I read somewhere on the internet that beta blockers can have this particular side effect. If so, will it get worse w/continued use of this medication? What would be the course staying on the medication? If this is indeed the case, will d/c this particular beta blocker resolve this issue? Don't worry, I'd rather treat the issue the metoprolol is for, than to have a straight penis; I'm a long term married person and my wife and I both realize that love is very different than sex and life is very different from a fatal MI! But, I am interested in the course of this apparent side effect of beta blockers. It's my only penis! Thanx for your input.

Various evidence suggest beta blockers can contribute to PD. If your cardiologist can switch you to a non beta blocker, it would be a good idea. MG

Dear Doctor Gelbard , have you heard of anyone having success with PD by taking Neprinol? It is suppose to dissolve the scar tissue according to their information on the WWW.

There are reports of it helping, though nothing in the way of controlled scientific studies. MG

. I am 34 y/o and noticed some minor pain when erect approx 8 months ago. Probably a week or two later I noticed a bend had started approx an inch from the head of my penis bending upward. Now the minor pain has for the most part subsided and the bend does not look to be getting any worse (other than I have lost approx 2 inches on my erection) I believe i have Peyronies and I am wondering will the bend get worse or will the pain come back? It has not effected my sex life with my wife but I also have not mentioned any of this to her (shes pregnant so our sex has slowed down a bit)

August 2009

After 8 months it would be unlikely for the pain to come back or the bend to get worse. MG

August About 2 months ago I woke up with "the curve". It goes about 30 degrees upwards and I have pain when I have an erection. From what I have read in the forum Here are the remedies: 1) wait and see plus Vit E remedy 2) suggestion of Potoba for 3 months. 3) Verapamil injections which apparently cause some bruising. I have not been to a urologist but from my symptoms it seems very obvious that I have PD. I am 58 years old and this occurrence has been very disturbing. Any suggestions regarding initial treatment.

I would suggest vitamin E plus colchicine, in conjuction with a series of verapamil injections. MG

I am a 56 year old who is very active sexually with my wife and in the past 3 months I have had some soreness, redness and lesion around the head of my penis and sometimes to the point where I feel like the skin of my penis becomes really raw and sensitive to the touch. Is this PD?

No. MG

In your most recent reply, you stated that "[…] correction of curvature that has been present and stable for more than a year or two is very unlikely with any medication." Does that mean that there's no use for vitamin E-treatment when the accident has already happened a year before and thus, scarring has finished? In other words, may vitamin E only help during the period of healing, i.e. inflammation?

Most evidence suggests the early use of medical (as opposed to surgical) remedies; they seem to be most effective in the first (inflammatory) phase of PD. MG

Can daily moderate exercise such as walking and swimming help facilitate the problem of decreased blood flow as a result of Peyronie's ?

Although Peyronies may be more common in men with conditions contributing to decrease in blood flow, the disorder itself is not usually considered a cause of this. Of course, exercise is always recommended for the preservation and improvement of circulatory status. MG

I am 26 years old, and approximately 9-11 months ago, I noticed that I have a curvature in my penis, which fits the exact definitions of PD which I have seen everywhere, including your website. I haven't experienced any pain during erections, and have been able to have regular sex. On very few occasions, I had experienced softening during intercourse, but I am worried this will increase. I believe I got PD from several encounters with my girlfriend where we would get agressive sexually, but with our clothes still on, so maybe all the extra friction (perhaps zippers, buttons) caused some sort of trauma. I am thinking of trying the vitamin E solution on my own, but are there any off the shelf ointments you recommend?

Some physicians advocate the use of vitamin E containing skin lotion, in addition to the usual 400 unit capsule once daily. MG

Can you send me the names of doctors who specialize in the treatment of peyronnies in the New York City or Connecticut area?

John Mulhall MD at Memorial Sloan Kettering. MG

I'm 15 years old. My penis is curved to the left side. The degree is about 25-30. I don't think that my penis is hour glassed but I am kind of scared. I remember once or twice that I felt pain at my penis during masturbation. Three years ago I remember that while I was playing football the ball hit me at my penis and I got ache for the next 2 days. Is this normal, if not what should I do?

This sounds normal to me. MG

I am 70 years old. 18 months ago I noticed a curvature starting. It slowly increased but seems to have stopped about 6 months ago. I had a smaller than average size penis and seem to have lost a bit of length. I have not got any pain and do not see any abnormal signs of any thing else. For years I had a very slow urinating rate but this was rectified with prostrate removal 9 years ago. 6 months after the op the problem started again and I had a second op being told this was due to scar tissue. The problem was resolved except for first thing in the morning. The rest of the day is OK. The urologist who did the 2 ops has retired. I consulted with my GP who states he has no experience with peyronies and can only give me the name of an urologist about 150 km from the small town I live in. Can you comment on this and give any advice?

After 18 months there is unlikely to be further progression. If you are able to maintain sexual activity, I would probably not recommend surgery as loss of rigidity is a more common complication in patients over 70 years old. MG

I know there's no proven study that vitamin E will cure my PD, but I gotta try. In my research another supplement that I read about was Neprinol. Looking past the sellers self proclaimed success, are there any concerns I should have with the enzymes nattakinase & serrapeptase contained in this supplement?

Vitamin E is commonly used even though proof of efficacy is lacking. I have heard some related improvement following the use of Neprinol, but there are no controlled studies confirming this. In the final analysis, they are unlikely to harm you. MG

Could you comment on the Heat Therapy process for PD? Is it simply a hot bath at 104 F or what?

I've never heard of it. MG

 

July 2009

I am 23 years old, and I've had a curve of about 30 degrees to the left for the last 5 or 6 years. I've lost about an inch in length some girth also...from what I've read I believe this to be Peyronie's. I was wondering if you've had any experience with Peyreton from Gordon's Herbal Research Center? They have a herbal formula (you can view a list of the ingredients on their website - Peyreton.com) which they claim has a 92% success rate. They also have a 30 day money back guarantee, if results are not noticed within 30 days. I have searched far and wide for information about 'gordons herbal research center' and 'peyreton', but I can't find any 'unbiased' opinions or testimonials! What do you think?

Unfortunately claims made by the seller mean nothing. It's up to you to decide, but correction of curvature that has been present and stable for more than a year or two is very unlikely with any medication. MG

I'm 62 yearsold and have always wanted to know about my bent penis. Thanks to Clinton I found out that it was a disease.

OK. MG

For about three months now, I've experience moderate pain along the top of the shaft of my penis when having an erection. I am also more sensitive during intercourse to the point where it is very difficult to endure unless my wife is fully lubricated (usually with a gel). There is no curvature of the penis that I can observe. I do not remeber any injury. I also have had BPH for several years. I'm 63 yrs old and was very sexually active in my youth prior to meeting my wife, during which time I contacted genital herpes which is controlled by stress management and the use of a daily tablet of lycine. My wife and I have had, and continue to have, a regular and satisfying sex life for the 35 years we have been together. Is this likely Peyronie's disease or are there other possibilities?

With the degree of pain and its relationship to erection / sexual activity, PD is likely. If the pain was due to herpes you would have seen some skin lesions by now. MG

I am a fifteen year old haemophiliac, and sexually active. After noticing some pain in the top of my penis during erection i assumed it was something to do with my haemophilia interfering with blood vessels in my penis, possibly an internal bleed due to overly vigorous intercourse. I waited a week or so, and i found out that the pain was connected with vein-like structures in the top of the shaft of my penis. I ignored these for a few more days, and found that so long as i left my penis alone i did not have the pain. Then, yesterday, i realised that the vein-like structure i had noticed was extending along the top of my penis, and causing a lot more pain. So i looked up "painful vein during erection" and i realised i probably have Peyronie's disease. This is, obviously, extremely disheartening for me to hear as a fifteen year old boy, and i was wondering about the long term effects. I have not noticed any curvature on my penis, but it is becoming painful to pull on while flaccid.

This is not PD but superficial vein thrombosis or Mondor's Syndrome, which will go away on its own. MG

My problem is located on top about three quarters down. Is there a topical sauve or ointment that will soften or break up this area?

Vitamin E and Verapamil have both been used topically, though there is little evidence they will break up the plaque. MG

I am 62 and have had a mild form of Peyronies for the past 10 years with no pain for the past nine years. In April, I suffered a hernia in the groin area about two inches from the base of my penis. I have put off having it repaired until this fall and have not had any pain from the hernia but have noticed that my peyronies is getting worse with some pain. I am concerned that the hernia may be affecting my peyronies and when I have surgery will this affect my peyronies even more. My question is can a hernia effect peyronies and is immediate surgery the right thing to do?

I have heard of Peyronies disease coming on after a hernia repair with plastic mesh, but have never seen aggravation of existing PD due to an inguinal hernia repair. MG

I noticed a curvature and PD symptoms around Jan. 2009. The bend was slight, but still bothersome. The doctor easily found the scarring on my left side and wanted to just start me off on Pentoxifylline (400mg) 3xday and L-Arginine (500mg) once a day. I also decided to take viatmin-e once a day on my own (as suggested by reading the forums here). Luckily I was also able to obtain a pump from my doctor and have been using it every other day for fifteen-minute increments. I have not noticed any improvement, and it appears to be getting slightly worse (granted it has only been 1.5 months on the pills and 1 month with the pump). Getting through to my doctor/nurse is a bad experience. I think his nurse doesn't take my calls seriously and it takes 48hrs to respond to me. Eventually I just skipped the nurse and called scheduling directly because the doctor is usually booked 3 months out - and my follow up isn't for another 2 months! If things are getting worse (even slightly) I want to do something about it! I called to see about an earlier appointment or to set up ultrasound treatments - and finally the doctor called me back directly! I expressed my concern about the underlying scar worsening and my overall concerns - especially with curving, tension/tightening and hour glassing. He told me not too be too worried about the time before my appointment and that "the scar is going to do what it is going to do regardless (of intervention)." that just sounded like a bunch of BS to me! If there was treatment now, I think it would prevent things from getting worse - attacking it now while it is in progress would be the best thing to do (using my logic)! Should I seek help elsewhere ASAP?

I think at this point a second opinion would be a good idea, if for no other reason than to find a doctor you can communicate with. MG

 

June 2009

I am 22 years old male, some time ago I started to "train" my penis. I was doing kegels and exercise which push blood into penis to extend tissue. I have not been doing them for a few days now. After 4 days, my penis shrank, and became kind of stiff in flacid state, especially at edges of the base. Now it is sometimes OK, sometimes it gets stiff. The head of penis, the top of it is cold as if it was something with the blood circulation. It also hurts sometimes in the base kind of impuls ache. Can it be PD?

No I don't think so. Maybe you should train some other part of your anatomy. MG

I am a 65 year old male who has Dupuytren disease contracture and Lederhose disease. I now have Peryonies disease. Vit E does not help, I was normal about 7 inches now I am 4 inches no curve, no pain but size does make a different. I have had surgery on my hands, the Lederhose disease really has not affected my walking, so have done nothing. What is the best way to increase my length?

Surgery will usually not restore length lost to PD. You could try one of the traction devices available over the internet, such as Andropenis or Fastsize. MG

My GP just diagnosed me with PD and have recommended that I see an Urologist that specializes in PD. I've had the problem for about 7 months and wasn't real alarmed because I didn't have any pain when flaccid. Right or wrong, knowing I had an annual physical I just waited. I've read that vitamin E orally may help (nothing proven clinically). I was wondering what you thought about messaging vitamin E on the outside of the affected area? Would you know of danger/side effect just trying?

There would be no harm to using a topical vitamin E preparation. MG

I am 61 years old. Suddenly, during sexual activity, my penis had a pronounced indentation near its base. This dent might measure about 1/2 inch. I also have had some mild pain while being erect. This indentation was not visible just 24 hours earlier.

This would likely be Peyronie's if you were able to feel a plaque / nodule near the area of narrowing. MG

I had peyronies 30 years ago and it eventually corrected itself. It has recently reocurred ( less than 3 months); at a different site and with differing impact ( there is less curvature and more indentation). My GP and I have decided on an aggressive treatment protocol. It consists of daily dose of 5000mg Vitamin E, daily doses of Pentox as well as daily low dose of Cialis; any comments on the efficacy of our proposed remediation?

Your approach makes sense, as all 3 agents are currently being used to treat PD. Unfortunately, despite a fair amount of clinical use, there is no published data on the effectiveness of these drugs in combination. MG

 

May 2009

Could you tell me how much Vitamin E I should take daily to help treat PD?

400 IU per day. MG

I'm 28 years old and about 6-8 weeks ago felt a dull pain in my penis during erection. This pain has progressively gotten worse, to the extent that erections are too painful to have intercourse. A couple of weeks back a notices a downward curvature to my penis that did not exist before. I went to a urologist about 3 weeks back, but he didn't diagnose me with PD. Given, there was no noticeable curvature at that time. I'm hesitant to blame the doctor, but I definitely feel he did not do his job. I plan to visit another doctor for a second opinion soon. However, my primary question right now is regarding the pain. Can you please help me and recommend something that will control the pain so I can be sexually active again? Also, can sexual activity worsen the condition?

Not likely to worsen with sex - ibuprofen will help with pain, which will probably resolve on its own with time. MG

During sex over two months ago I experienced a very unusual pain. I saw a urologist and he checked for scarring but came up negative, checked my urine and that too was negative for anything. I then had an ultra sound done and that too came up negative. My penis now bends upwards, starting half way towards the tip and my erections are pretty painful. I also noticed that the more sex I have the more painful it gets. Any Ideas? Should I get a second opinion?

Yes, this sounds like PD. MG

Have there been any studies of the Krishnamurti penile dermal flap operation for Peyronie's that is being performed in India.?

No additional published studies that I know of. Most reconstructive urologic surgeons use free grafts rather than flaps for PD as they eliminate placement problems that can be an issue with flaps. MG

My husband is 67 and in the last 6 months treated with radiation and seeds for prostate cancer, which is now taken care of we hope. We have been married for a year and sexually active for 3. He has always said that he feels he is "hitting" the back of my vagina during sex and has to pull out somewhat so that ejaculation can take place, or he thinks it will be blocked. He has mentioned it feeling painful to have full penetration sometimes. In the last few months we have noticed a dent in the lower half of his penis that was not there before. Could this have been caused by hitting the back of the vagina and bending the penis? Do prostate issues or treatment cause anything like this? And finally he has no other bumps or changes so is the Peyronies and what are the odds it will heal on its own or get worse?

I don't think this is due to "hitting" the vaginal walls; the indent and pain sound somewhat like PD to me. With the lack of curvature I do think it will heal on its own. MG

I am 17 and my penis curves downwards when erect. It goes straight for about 2 inches and then it curves down and the straight part is skinnier than the downward. When i am soft you can see that the beginning of my penis is skinnier than the rest (as if it has less 'meat'). Sometimes my erections don't last long or they'll be hard and then slowly turn soft. Can i still have sex?

Yes. MG

My penis has been curving to the left ever since I can remember. I had surgery as a young boy to correct a urinating problem. Would the scar tissue from that procedure be causing the curve, and could it be corrected.

Yes to both questions. MG

I am 59. My questions are 1) has anyone with PD had a penile pump installed in them that you work manually and was this a successful procedure? 2) Has anyone with my age, health problems etc just let PD progress and what happens when they do? 3) I live in eastern Iowa and am 3-1/2 hours from Mayo and 4 hours from Chicago so is it worth it to me to get a second opinion and where would you suggest I go? 4) I'm not quite in the acceptance stage of this yet and from my research I don't see a lot of success stories out there. What are the chances of any procedure working for a person my age with severe peyronies?

Inflatable implants can be very successful in the right candidate. Getting a second opinion is always a good idea prior to surgery. MG

I have an enquiry and i was wondering if you could help me. My husband has been diagnosed with PD disease, he is 58 years old and his problem started in december 2008. Mu husband has never been circumcised, but it has never been an issue for any of us. his doctors says the first he is required to go for a foreskin operation, before he is treated for his PD treatment. I would like your opinion on this, since his surgury is schedule for July 2009 and time is running and my husband would like to start doing something about it before the surgury. We have ordered Niprinol and Serra and we have also thinking of buying the vacumm pump machine, i was wondering what your advise would be. Also is it true that recovery for the foreskin operation is between 5 to 6 weeks?

Sexual activity can usually be resumed about 3 -4 weeks after a circumcision. I would agree the neprinol and pump are a reasonable course of action at present. MG

I am 58. For the last 6 months my wife has had to hold the base of my penis during intercourse because of "soft" erections. I figured because of my age, I could no longer expect rigid 18 year old erections. Two weeks ago, I took 10 mg of Cialis and to my dismay there was a 60 degree dorsal angulation of my penis. My urologist suggested vitamin E for the next 12 months and then possible surgery. Any other suggestions ?

That sounds like a reasonable proposal to me. MG

Being diagnosed for 6 months, I have been on a daily of 400 ui of vit E along with L-arginine 1000. with no significant change. I have been given one opinion that Verapamil 15% Gel applied 2X daily along with hot tub treatments for 3 to 6 months have shown to have a fair succes rate. Any coments?

Unfortunately none of those medications has good peer reviewed data proving effectiveness. So if they're not too expensive, a trial is worthwhile. MG

My boyfriend has been diagnosed with Peyronies for about a year now and I was wondering what would be the best ways to support him. I don't want to mother him but at the same time if i go about life like normal he seems to get offended and feels that i am not supportive. What is the best way to go about this. I want things to get back to normal because it's affecting our relationship yet i want to give him the support he needs to get through this.

Acknowledge the problem and see if he wants to talk about it, but if it doesn't have a bad effect on your sexual relations you should reassure him about this. MG

after dealing with PD for about four years I located a very experienced doctor in Philadelphia who had done a number of surgical grafts and plications for Peyronies. I was hoping for the tuck (plication) because it held the least amount of risk, but the doctor told me that due to a narrowing or indentation on the side of my erection that I needed a graft. The surgery was done in November of 2007. The doctor told me to wait at least six weeks before attempting intercourse. When I finally did I found I needed the Levitra he prescribed most of the time. The improvement from the surgery was acceptable at first, but after several months my wife began to complain of pain again due to the curvature returning somewhat, maybe to about 15 or so degrees. I was pretty upset, thinking that I went through the surgery in vain. My wife and I had gotten to the point a few months ago where we simply decided to have only manual sex to keep her from having pain and to allow us some semblance of what we once had. Ironically, during the manual sex period, we discovered, due to experimentation with foreplay, that I was getting a better erection without Levitra than I was with it. So we then attempted intercourse without medication. The problem was that although the erection was generally good, I would lose it at the moment of attempting penetration. I wasn't sure if it was performance anxiety or not so I contacted my doctor about an erection ring as I had read that this was a way to keep an erection if one was possible normally. I discovered that the erection rings sold on the internet were pretty much junk and you could actually hurt yourself with most of them. My doctor recommended a product called Actis which can be found at www.vivus.com/actis. It's an elastic band with a small ball at one end that acts as a stopper and a small slider that snugs up against the ball to keep tension on the band. I would not use it until just before intercourse, making foreplay more natural. This device solved our problem. We have been having intercourse normally for the past three months and my wife has no pain anymore. I don't know why except that although the curvature is still there, but to a lesser degree, and my erection feels more normal to both of us. Sex finally feels normal again and we are so relieved to once again have what we had lost for over six years. I am not affiliated in any way with the Actis company and my story is pretty unique as I imagine most stories about this disease are. I would like to add that I have been working out at my local gym regularly for the past three years and it's possible that this may have helped my condition. I did notice that I no longer have to get up once every night, as before, to urinate and the weak stream that had been frequent now occurs only on rare occasions since committing to regular exercise. I want to let other sufferers know that surgery can be a good option when all else fails, but that patience is of utmost importance, as is having the hope that success can happen even after several years of frustration. Most important is to find a good doctor with plenty of experience with whom you can place your trust.

Thanks for the submission. MG

I am 52 and have recently been noted to have PD. After taking propranolol for 15 years for benign familial tremors, is there reason to believe stopping the drug will allow reversal of the disease (if it is indeed the cause), or the plaque is what it is, and stopping the drug might prevent further disease process only.

If the PD is progressing, it would be wise to stop the propranolol. If it has been present for more than a few years and is stable, there is probably no reason to stop the medication. MG

I started to notice a slight bend on my penis about 10 months ago. I havent taken any medication or any seen doctor. I would like to highlight that i am only 19 years old. Now i think i have quite a significant bend of about 30 degrees to the left from actual straight erection. I am still a virgin and really dont know what is to be done. Could i turn impotent?

I seriously doubt that. Probably a good idea to see a urologist. MG

April 2009

April 2009 My husband recently had surgery to correct his peyronies curvature. The surgery was a success and the curvature has been greatly reduced. The issue isn't with the surgery but with the cost of the surgery. Our insurance company had approved the surgery; however, six months after the surgery was completed they are now saying that the surgery was for cosmetic and sexual performance and are refusing to pay for the surgeon, hospital, etc. Has anyone in this forum experienced a similar issue and found a way to get their insurance company to pay for the surgery. We are very pleased with the results of the surgery but we weren't prepared to pay almost $20k for all of the medical bills. Any suggestions would be greatly appreciated.

I'll put it out to the readers. It sounds like you need to vigorously pursue an appeal to your carrier. MG

My husband of 40 years developed PD about 5 years ago. It was a physical and emotional blow to both of us as we had always enjoyed an very active and satisfying sexual life. For the first year or so we tried to avoid intercourse, me for fear of causing him pain and him for fears of not being a satisfactory lover. We have both more or less accepted and adjusted. I think I just want others to know that it's not the end of the world. Yes, things happen and life changes but the intimacy can still be part of your relationship.. Get creative and find other ways to please each other. Thanks for this forum.

Thank you for this contribution - I think it will be helpful to some. MG

Hey, Whats up Doc. How are things progressing with the trials for Peyronies . Im looking to--I guess be a --well yes, ha--to be a guinna pig---so to speak. We mailed to and fro a while back---hopeful and still waiting here patiently.

It looks like things are still moving ahead - I believe Auxilium will be sponsoring a phase III clinical trial for Xiaflex® (collagenase) in 2010. MG

i'm 18 years old, and just went to a doctor today, and i figured i must have peyronies, and have had it for as long as i can remember. erections curve to the left slightly, and bend upwards about 170degrees. the inconvenience just bugs me moreso than the actual pain because i dont know if it's going to cause something serious. at the moment i've just left home, and i'm doing an apprenticeship and only have around 50 bucks spare/week. one website said they can sell me tablets for $90 (www.peyrotin.com) that are guarenteed to treat the disease, should i buy these or what do you recommend i do?

First off, you don't have Peyronies, so don't buy any pills. If you have a problem in the future with your congenital curvature, you'll have to find someone to perform a Nesbit procedure which is very effective in curing this bend. MG

i' m 16. My penis is bent approximately 45°, but i don't have any pain on erection. does tis necessarily mean i have peyronie's disease/ No, you probably don't. This sounds like congenital curvature. MG how do you know whether penile shaft bending is peyronies or just bent penis? mine bends off wildly to the left, and also points down, and does give me a degree of pain on erection. would just like an answer after years of not knowing. cheers x

Peyronies usually comes on in middle age, sometimes after sexual trauma, in a patient who previously had no curvature. If bending has been present since adolescence, this is likely not PD, but congenital curvature. MG

In June 2005, I suddenly had a bent penis. As best as I can recall it occurred overnight. I believe it may have been caused by entanglement in bed clothes during nocturnal erection. However, that's just my speculation. I believe as possible contributions to the condition might've been my lack of use of vitimins and dietary supplements. At that time I had developed some osteopenia which I believe was either caused by or contributed to by defective digestive abilities. At that time I wasn't using digestive enzymes to aid my body in its ability to process nutrients. I looked up information about Peyronie's and started dosing with vitimin E. This helped straighten the shaft back to a reasonably straight direction, but ever since my penis has been three inches shorter than it was. My penis always measure 7 1/2 inches (19cm). Now it's about 4 or 5 inches. I spoke to my doctor and also to an urologist about this. Either they were doubtful, or didn't know what to tell me. I saw on this site that one can indeed lose penile length.

Length loss is common with PD, and despite the improvement with curvature one can see with different treatments, unfortunately restoration of length is unlikely. MG

Hey, Im 23 and i have a 20-30 degree bend to the left in my erect penis. The right side of my penis is alot bigger than the left side. Also my flacid penis bends hangs to the left. Ive noticed the bend for about the last six months. I now have a big vein running on the left side of my penis right next to my vas defrans i never noticed till about 2 months ago. I have no pain or erection difficulty but my penis is constantly hanging left even when flacid. Its becoming very uncofortable for me to just sit because i always feel my flacid penis hanging to the left, and feel like im constantly adjusting it. I cant really feel any bump or plaque in my penis, i can feel the new vien i was just talking about though. Also if i put my limp penis to the left it will just stay but if i put it to the right it will go back to left as soon as i let go. I doesnt seem to be getting any better. Does this sound like pd or something elese? I appreciate any advice you can give me thank you

This does not sound like PD to me. MG

I have had ED for several years. Viagra worked well for me. About 5 months ago, I slipped in my kitchen and my penis was rammed into the kitchen counter with my body weight behind it. It hurt for a few days, but I didn't worry. Last week I finally went to a urologist and he found 2 hardened areas on both sides of my penis, and diagnosed it as PD. The lumps are hard. My erection is deformed, not bent. It only engorges with blood about half way up the side of the penis when erect, then it looks like an hourglass, with the head of the penis slightly enlarged. He ordered blood tests to see what the cause of the ED was. Anyways, he suggested I use a vacuum pump a couple of times a day. I always forget to ask doctors questions. My question is the purpose of the vacuum pumping. Is this to enrich the penis with blood, pulling more blood into that area in an effort to increase blood flow, or was he suggesting I use the pump prior to intimacy? If the purpose were for sexual intercourse, it doesn't seem to be working. Would massaging the plaque help to reduce it's size?

The vacuum pump is to help stretch out the areas constricted by scar tissue. MG

What do you know about Verapamil cream. i was told by someone at a male clinic that some doctors are finding that it really helps and a lot of people are getting cured. is there any formal research on it?

There are no good peer-reviewed scientific data proving that verapamil creme works. MG

 

March 2009

three yrs. ago I became aware of a small bee bee size bump kinda near the base of penis shaft. I researched on line to finally find out about peyronies. to a doc I went and -no testing -verifyed I had Peyronies-said maybe I should try vit E and in some cases it just goes away. In time -I called his office again and found that he had gone away but peyronies wasent. for the record -I never experienced pain-couldnt remember an injury to the area. I have always wondered about some of the physical extreme feats I accomplish-As a framer -monstorously heavy lifting-As well -some 15-20 mile back country runs--maybe a severly torn calf muscle from a basketball game bleeding internally and gathering in the foot and ankle---added to the above-taking glucosamine and condroiten to help to counter for the physicality at age 51. Ive seen 6 doctors with no testing -really all saying come back in a year--Its been three years- Can scar tissue (now having been inactive ) physically and sexually for three years continue to grow and change penis structure-Its apparently happening but makes no sense to me--Penile prostesis--Does anyone know about --normal sexual sensation-satisfactios and drive associated with such. ???

Peyronies can continue to change the penis shape / structure over this time, though it usually stabilizes after 12 months or so. There may be a relationship between taking glucosamine & chondroitin and getting PD. In cases of severe function loss due to PD, a penile prosthesis can substantially restore function and satisfaction. MG

I am a 37 years old and have had a curveture of the penis since about 13 or 14. I believe it was due to a trauma to my penis by being kicked.My penis curves approx 45 degrees to the left, and the curve starts at the same spot where the bruise was.Sex is uncomfortable in certain positions, but it is painful for my wife. If there is scaring and damage, will surgery correct this?What do you recommend?

As this has been present more than 20 years and causes discomfort in your wife, I would recommend a Nesbit procedure. MG

I am a 22 year old male. I am not very active, but I do try to eat healthy(drink alot of water, not so much junk etc). I woke up one day with a pain in my lower left torso. It kinda felt like a balloon. It wasn't till 4 days later it started hurting. On my way to the doctor, I felt my penis contract and when I reached down I felt a big ball at the base of my penis. Sorta like it was a ball, then the penis started. I freaked and thought it was a kidney stone and went to the hospital but CT scans and urine and blood tests told me I was fine. I still have lower left torso pain that was starting to creep up to my side and my lower left back but now my penis really hurts. I feel like something hard on the sides of my penis and it feels like it's just contracting alot. Could this be PD?

I don't think this is PD. MG

I have been diagnosed PD by my doctor (a General Practitioner). About 4 months ago, quite suddenly, I lost erectile function in the end inch of my penis. My wife noticed it first, saying my glans seemed not to be so hard anymore. I first thought a band 1" wide just under the glans was constricting the penis from expanding, as there is a 'shoulder' at that point where the normal width stops. I took a photo of this while erect (not easy) and showed it to my doctor who was at first perplexed but then, considering some other of his patients who have had recent right-angle bends occurring, typically PD, decided I probably had Peyronies. In recent months I experience a definite cut-off point an inch below the glans where the erection stops and the rest plus the glans is quite flaccid. I have experimented with compressing the erection (like a cow's teat) and trying to extrude the blood along into the flaccid bit, but worry I might make it worse. It's a worry to me as another apparent effect is that erections dissipate more quickly. So during sex a slight erection drop-off seems to make penetration more of a problem. Is this a result of pd?

If narrowing of the corpus cavernosa occurs due to PD, structural weakness of the erection can result from the failure of this segment to expand to normal diameter - it is a consequence of elasticity changes in the wall of the corpora, not restricted blood flow. MG

I'm 17 years old and have had a bend in my penis for a while now. At first, I thought it was due to masturbation since it is bending to the left when erected and turning slightly clockwise, but PD seems more likely now. When limp, it is a bit larger at the base and it still bends a bit towards the left. Do I have PD?

Sounds more like congenital curvature. If this creates a problem for you, a visit to the urologist would be a good idea. MG

I was in an automobile accident last May 2008. I was diagnosed, among other things, as having abdominal pain when examined in the ER. Upon having to urinate in a receptacle in the ER, I told my wife that I had no sensation of urine coming through my penis. She assured me that it was. The next day I developed what i described as "groin" pain, which worsened over the next couple of weeks and seemed to move to my tailbone before disappearing altogether. In early August I noticed that my erect penis was "bent" at the base. I went to my urologist who diagnosed me as having Peyronie's disease. Under the assumption that from approximately nine months prior to the accident until now 03/09/09 I have not had sexual intercourse, would it be reasonable to conclude that my Peyronie's was caused by the accident?

That does sound reasonable. MG

I had PD corrected 12years ago with surgery that went quite badly. I had a gross haematomy and severe stretching of my penis and was not fully sorted until about 4-6 months after the surgery. The problem I know have is where the surgery corrected the bend I have 2 halves and they have pulled apart slightly and they sit slightly right and left of each other. Where the problem is, while erect I have an area that sticks out on the right hand side quite sharply and it causes some discomfort when using a condom as it rubs on this area. Also I am causing pain to partners as this area becomes hard when erect. Is there any medication I could use, or would this require further surgery to sort?

I would recommend you get photographs of the erection and visit a urologic surgeon with particular experience in reconstructive & peyronies surgery. MG

I am 20, about two weeks ago I noticed a very, very hard small lump on the right underside of my penis close to the head. It seems to feel like it's attached to some kind of cord. I think this could be related to masturbation as i can remember maybe 3 weeks ago being a little rough. I am now experiencing a litlle bit of pain, but its it tolerable. No change in shape of my penis. The lump has not increased in size in the following two weeks after I noticed it. I was wondering if there is a chance I will be stuck with this small lump (which does not bother me), or does this scar tissue always increase in size? If so why is this? I have an appointment with a uro coming up, and fear that I will be diagnosed with this. Is there any reward in early diagnosis with this problem?

It appears that medical (pharmacologic) remedies for PD work better in early cases. MG

I am a 39 year old male who has Dupuytren disease contracture and Lederhose disease. I am fearful now of contacting Peryonies disease as this falls into the same class of diseases. I am not a big fan of surgery. For my dupuytrens, I choose a non surgical procedure called needle appendectomy. Since my lederhose disease really has not affected my walking, I have done nothing as I have not found any non surgical treatment for it. In the event I do get PD, I have been searching for non surgical treatments and have found only one that has some scientific evidence to back it up. Does anybody know anything about this? They claim to be FDA registered. Not sure what the difference between registered and approved is? www.androman.com

There is a different standard for drugs and devices. Registered means the FDA has been given data about this device, but that the FDA does not attest to its effectiveness. There is some preliminary evidence that stretching devices such as this may reduce bending due to PD. MG

I am 45, I developed PD 2 years ago. I have around 30 degree curvature on right with indentation in the middle of shaft on erection. I am taking Vit E 400iu daily. Length and girth significantly reduced. Do you think these Traction devices will help to reduce the curvature and increase the length and girth. Is there any harm to use them or can they worse the PD?

Please see the above submission. If used properly, these devices should not cause harm. MG

I've heard about verapamil cream from a doctor at a male clinic. he advised me that he had a dr friend that has been using it to very good effect on patients. what do you know about it?

It may help PD, though the data on topical preparations is somewhat conflicting. MG

February 2009

I am 55 and just about 5 months ago I noticed a curve in my erection for the first time. Since then it has progressed to an irregular shaped erection. It is normal from the base out for 2 inches then there is a bump or ridge on both sides that is about 1/8 inch high and 1/8 inch wide. From that point on my penis is only semi hard and a noticably smaller in diameter and a little shorter when hard. I can't feel or see anything unusual when flacid except it feels mushier than when I was younger but that has been happenig gradually as I aged. I have also been using viagra or callas for the past 5 years most of the time for sex. I don't think I had any trauma other than the time I was painfully cathed after my thyroid was removed year ago. Is there any thing I can do to fix this and what does the future hold for this. Could having sex with a very weak erection on the front half of my penis add to the problem?

This does sound like PD, which is likely to stabilize within 12 months but may produce some permanent deformity. I would suggest you continue to use viagra or cialis as intercourse with a weak segment may lead to bending and further trauma. MG

I am only 18 years old and a urologist diagnosed me with PD. It started around a year ago with a faint pain in the tip of my penis when I had an erection. It developed very slowly to a more noticable pain, and then once I noticed curvature about 6 months later I went to see the urologist. they curve got worse to about 30 degrees but then I noticed that that part of my penis wasn't as rigid any more during erection. I have a large hard bump near the head ofmy penis and it still seems to be growing (but I might be imagining it). I really don't want to lose my sexual function so early, what should I do? I am taking vitaimin E since I saw the urologist. Is it likely that the disease will continue to get worse and worse?

Not likely, it will usually stabilize within a year, and at your age considerable improvement would be expected. MG

can you use viagra if you have peyronies

Yes, and there is some evidence that this class of drug actually may have a beneficial effect by inhibiting the process of scar formation. MG

I am 28 and now i notice the curvation of my penis. Now i am doubting whether or not it had always been there. The curvation is strongest when my penis is 'half erected'. Then it bends firmly to the left. I notice the curvation gets less when my penis is totally erected. Then it feels like it is difficult to break 'through' till i have a total erection. Till now, i feel no real plaques and no pain. But i do have some erection problems now and then. This could have other reasons then PD.

This sounds more like congenital curvature, not PD. MG

I am 63 and recently found my penis to be shaped differently. I used to have a slight curve to the left and similar circumference for the entire shaft. Three months ago I discovered my penis to be shorter,much narrower at its base and larger in the center. I have no bumps. I am able to have sex however penetration is difficult because of the bending at the base because of the narrow shaft. My urologist advised I have peyronies, that there is no pill or cream that will fix it. He suggested a pump to help stimulate the narrow area at the shaft. He suggested only time will tell if I will be cured. I read about different types of medication and creams in your posting. Is this pump a reasonable approach. Do you recommend a second opinion with suggestions towards medications or creams.

The use of a vacuum pump is a reasonable approach. A second opinion regarding the various pharmacologic remedies used would also be a good idea. MG

I have been scrolling down your web page hoping I would find that sufferers of this condition have been taking (like me) an anticoagulant (e.g. Warfarin/Coumadin) for a long time. I have been taking this medication for over 20 years and have developed in the last 3 years an upward bend in my penis about one third from the base. My GP said that it was fairly common and called it, something like, "Priapus" or the closest medical term, but not what you refer to it as. She suggested that I do nothing and that it may cause some sexual disadvantage but at my age (70) that is not an issue. It is true that my penis size has decreased a little in length but only the part from the bend to the tip of the penis. My philosophy is to make do, the best you can, with what you've got, when you can. Sex isn't everything, and it can certainly make you a slave to it, if you let it. Just wait 'til you get the the "prostate" part of your life and the "bent willy" will seem so insignificant.

There is no known association between the use of coumadin and PD. MG

I have read many of the e-mails and feel for the people involved. My question is a little different. I have been dating a 60 year old man for a touch over a year. He has PD. It curves upward and back toward his tummy. He has erections and release however, it is a challenge sometimes to find a position that allows him to enter. As well, more and more afterwards I am finding that I am sore in a strange place (this would be where his curved penis hits) and it takes a couple of days for it to go away for me. Could this be damaging me as I even feel this soreness when I urinate. I have gone to the doctor and I am fine but did not tell her about this. Any suggestions? Is it possible that a severe case of PD can hurt a woman?

PD cannot damage a woman, but it certainly can cause discomfort if the bend is significant - usually irritation of the urethra (burning with urination) due to upward bending. Using a lubricant such as astroglide as well as a bath afterward with domeboro bath salts (both available over the counter) will help. MG

I am 68 years old & have had little difficulty with erections. About 2 months ago, out of nowhere, my penis was bent about 45 degrees and was painful during erection. At the location of the bend, I could feel a hard core which was very narrow & less than a half inch long. I was shocked. Since then, the curvature seems more pronounced & the hard core is a little longer, but the pain is very slight. Does this sound like Peyronies & does the sudden nature of it appearing suggest early stages? What next?

Yes this sounds like PD, and it would be best to consult a urologist. MG

I am 38 yrs old and about 6 weeks ago felt some pain in my penis duing sex discovered a hard pea sized lump inside the shaft about midway up, it is not visable but can be felt by squeezing the penis when soft. I can still get an erection however it is not as "hard" as it used to be and seems "deflated" in the area where the lump is, there is no bending or curving in my penis. The areas before and after the lump are normal when erect. The pain is now pretty much gone, the lump has not changed and I am able to have sex although it seems to take longer to get an erection and it will go soft quickly it not stimulated and sex is most certainly not as enjoyable because of that. Given my age and symptoms Is it likely the condition will worsen, improve or stay the same?

At your age and with six weeks of duration, it is likely this will improve over the next 12 months. MG

i am a 52 year old male, i recently noticed what i can only describe as a bulging area an inch or two above the base of penis, it feels like cartilage has been split or broken i have this on both sides when flacid, when an erection is obtained it is not felt, but erection seems shorter and it feels stronger at base then on tip, almost like something fell back, there is no bending. but some pain at times, i am diabetic, and have high blood pressure and high cholesterol, and take meds for all

This sounds like it could be PD - probably best to be examined by a urologist. MG

 

January 2009

I have had peyronies for about 9 months now, 70 degree bend..ouch. My question is: Do you know why the the Lariche Technique they are using over in Europe that, for some reason is not being used in the U.S. and if it is going to be used in the U.S.. and what else do you know about it, if anything. Here is a description of the procedure. Operative technique: Patients are operated on an outpatient basis under local anaesthesia, after location of the plaque by intraoperative ultrasound of the penis with erection induced by phsiological saline. A percutaneous tear of the plaque is performed with an 18 gauge needle.

Although there have been successes with this procedure, there is a very real risk of nerve injury, as the nerves providing sensation to the head of the penis are immediately adjacent to the plaque (and to the blind incision created by the needle point). MG

I am a 54 yr old relatively healthy man I got this curse about 6 years ago, the reason I call it a curse is simply because it wasn't bad enough to have a small penis-then I come down with this thing-I have treated it with 400 vitamin e-with no change-I don't really know how bad I suffer from ed because of the pd doesn't help my self esteem ,while I show signs of ed I realize my age is probably most of the reason-and some lifestyle choices i.e. smoking and not enough exercise but this curse just makes me feel like I am falling deeper and deeper into depression and I know that has a lot to do with ed-so if I could find a cure or at least some relief-all would be well with the world

The repercussions of PD on self-image & esteem are real. I think the current research being done by Auxilium with the use of collagenase is promising and should provide a degree of encouragement. MG

The areas of plaque seem to have moved, is this normal?

Yes, although the plaque doesn't "move", it's just that different areas of the affected tissue get firm. MG

About 6 months ago I devolved either pd or a fractured penis. About a week or two after I noticed this I also noticed blood in my urine. I believe I did this by masturbating. I am 57 years old. My penis is now hour glass shaped bends slightly upward and is at least an inch or more shorter. What is causing the bleeding?

This could be due to an associated injury, but there are many other causes and any case of blood in the urine should be investigated by a urologist. MG

I am 44 and about two months back i noticed a harp pea sized lump on the left side of the shaft near the base of the penis. I visited the urologist who said it was PD and started me off on vitamin E 400 units per day. There is no noticeable curvature till now, or pain during erection, but i have noticed surrounding areas ( around the lump, on the shaft more towards the base as well as towards the glans) are also somewhat harder now over these two months. Does this sound like PD to you?

Yes, as time passes the hardness may appear in different spots, and then may resolve in the same fashion. MG

I am a 44 year old male who started experiencing moderate pain during morning erections about two or three months ago. Two weeks ago, I noticed two hard lumps behind the tip of my penis. I have no other symptoms, and my erect penis appears unchanged. I saw a urologist who diagnosed Peyronie's and told me to take 1000 units of Vitamin E each day and come back in 6 months. I'm wondering if I should expect the disease to progress, and if I should be taking any other measures to prevent further symptoms.

Vitamin E has been used extensively, but has no placebo - controlled confirmatory data. Neither do the following drugs but they are worth considering: colchicine, neprinol, trental, L-argenine, and phosphodiesterase inhibitors (Viagra, Levitra, Cialis). MG

I am a 23 year old of Cuban descent. About a year and a half ago, perhaps even 2 years, I noticed my penis points/curves to the left approximately 30 degrees when erect, may have lost a bit of girth when erect, and also appears almost twisted to the left when flaccid; I cannot tell if it is curved more today than when I first noticed. Additionally, when both erect and flaccid I can see and feel a small lump on the left side that I do not recall seeing before, which 'gives' a bit when touched but remains in the same location. When I first noticed this, intercourse with my significant other was painful (though only after; getting an erection was not painful unless it was directly after intercourse), though currently I do not experience pain with erections or after intercourse. May this be peyronies disease? If so would it be wise, in the interim before seeing a urologist, to try to bend my penis opposite of the curvature and/or massage the lump (my significant other has dupuytren's contracture, and was advised to massage her scar tissue to help break it up and slow its progress), or would this aggravate the condition?

This does sound like PD. Stretching or mechanical traction appears to help in certain preliminary studies - as long as it is gentle and not traumatic. MG

I'm 50 years old and have had PD for about a year and a half.It has really put a strain on my marraige.My penis went from a "normal" 7 inches to around 4 inches.It is straight but small at the base to normal size at the head. It also bends downward,but always did.It just doesn't straighten like it used to.I've been to a ureologist,but he just said surgury was the only way he knew to fix it.Ive read about stretching,but wanted to talk to my regular doctor before I tried that.I've also had a problem with premature ejaculation since this started.I never was able to go for "hours" anyway,but was always able to do just fine.So,should I try the stretching route

Yes, that would be worthwhile. You should talk to your doctor about using Zoloft or Paxil for premature ejaculation. MG

Around the end of summer I noticed I had an hour glass shape to my flaccid penis after swimming. Then recently within the past few months I have began to notice that often times it remains in the hourglass shape while flaccid, although I have not had any difficulty with my erect penis. I have not experienced any pain and do not seem to have any lumps on my penis. Also I have noticed that my penis seems smaller but it could also just be in my head. Does this sound like Peyronies?

No. MG

I imagine surgery can fix my condition of a curve in the shaft. Can surgery also fix a twist, or disconnect of a portion of the base of the penis? How effective is the surgery? What are the chances of it returning after surgery? What are the chances of surgery making the condition worse? would surgery risk shortening of the penis?

Surgery can correct twist as well as bending, but the risks depend on the anatomical location and severity. For instance, the risk of postoperative erectile dysfunction is higher in men with downward bending. MG

December 2008

my penis started bending when i was going through puberty. I am now 20 years old. If a perfectly straight penis is at 90 degrees when erect then i bend at around 160 degrees. I have no pain when having an erection however if i push it down to 90 degree position it does hurt some what. is it peyronies disease? and what can i do to correct it and make it straight? (so its 90 degrees from the body).

If this creates a sexual problem, surgery can correct the bend, though angulation of the penis upward at 45 -60 degrees is considered normal. MG

I am a 53 year old and about 6-8 months a go I began to experience some pain on the left side of my penis during intercourse. On the first occaion that I noticed it it felt like my penis severly bent during intercourse maybe causing some damage. Prior to that I had begun to notice some visible discoloration on the left side with what appears to be dark purple blotches. In the course of the past six months i now bend to the left at about 30-45 degrees and girth and length is reduced. I have been taking Lopid, Niacin and Lipitor for Cholestorol and Liprinisil for BP. In Feb 2008 I also had a stent put in y diagonal artery. This seems to fit the bill for PD. Can any of these medications cause the problem and can it be reversed if so. If not, should surgery be recommended at this point or will meds be more effective?

There is no evidence to suggest these medications cause PD. I would recommend you take some form of drug therapy for at least 6 months before considering surgery. MG

A little more than a year ago I had lasik surgery on my eyes. I have unusually large pupils and post surgery was having a little difficulty with night vision. My eye doctor then prescribed Betmonidine Tartrate drops which is a glaucoma medication that has a side effect of reducing pupil size. I also think that this drug is a beta blocker. For a good six months I was using the Bet. Tartrate drops almost everyday and sometimes twice a day. About four months ago, I noticed a hard lump on the inside of my penis around the top portion of the shaft and a little under the gland area like so many others describe. I notice some pain in my penis when I have an erection. There is a very slight indention near where the lump is but all looks pretty normal when fully erect..no bending and no loss of size. Other than the pain, all else seems fine other than my being completely paranoid that the condition could worsen. I started taking vitamin E but will have to wait to see a urologist because I'm currently in China and don't return to the States for a couple of weeks I have two questions: 1) I stopped taking the drops about three weeks ago and was wondering if ending the potential cause would likely reverse the peyronies lump and the pain or if the condition potentially brought on by the drops is one that can stay forever. In other words, if I stop the cause, will the effect reverse? Or can the scarring from the initial onset be just that..scarring that remains and I could have pain continually? I know I'm making a big assumption the beta blocker drops caused the problem and I do realize that it is still unproven. But I've never had any trama and other than flax seed, fish oil and regular vitamins, I don't take any other drugs. 2) If beta blockers are linked to Peyronies as a potential side effect, then do you know why there is not one word in the Bet. Tart. drug literature that mentions this? I'm really angry that it takes me doing my own half-baked research on the Internet about beta blockers and Peyronies to discover that while there is no proven link, there is a correlation between the two that goes unmentioned and does not even give me an opportunity to make an informed decision of whether or not I should risk taking the drug. That's just insane!

You are correct, taking beta blockers has been associated with PD. MG

I'm 46 and have recently developed an hourglass deformity. My Urologist recommends several medications including Pentoxifylline, Potaba and L-Arginine. He says there is no harm using all three at once - does that sound safe to you? A Naturopathic Doctor also recommends L-Arginine, but insists that a low dose will do nothing. No, he is not selling L-Argine. He recommends a very high dose - at least 3 grams per day and working up to 21 grams per day! Do you know of any risks to trying this? The Mayo Clinic reports L-Arginine can increase lung inflammation and worsen asthma.

The above drugs and supplement are widely used for PD. I would recommend avoidance of "megadoses" such as 21 gm per day. MG

I am 30 and was diagnosed with Peyronie's two years ago. I have a small lump near the head of my penis, on the left side. I also have another one on the base of the left side but no curve. Erections are Not painful, but when flaccid both areas are sensitive to the touch. Also, I have a dull sensation on the left side of my lower stomach that has been prevalent for a while. my whole left side seems to be effected, are these conditions related?

While PD is not known to cause abdominal pain, it appears that your genital pain could be a trigger point for something else. MG

I think I have always had a slight curvature to the left, but never thought much of it. I have since looked this up on the Internet several times. Now, I am somewhat concerned about the distinct bend on erection that occurs sometimes, more pronounced than the general curve that is always present. Reading about damage that can cause PD, I am aware that I have a history of occasionally intentionally bending a morning erection all the way to the left in order to urinate when sitting, as urine would otherwise go everywhere. Is this related to the problem? I have not had problems with intercourse. I have not experienced pain on erection. I do not feel any lump or spot that seems related to the curve.

I don't think bending the erection has been harmful. You have slight congenital curvature, not PD, and I would suggest you "live with it". MG

All my life I have had a slight curve to the left in my penis, I am 47 now, but it never caused any problems and was enjoyed by my partners. In August of 2005 I had a double fusion in my lower back from L4-S1. The surgery was unsuccessful. I am now disabled with failed back syndrome. During this procedure a cath was used and left in for a couple days until I could get out of bed. Since then I have been diagnosed with PD. I have an indentation about an inch and a half below the head of my penis and it also bends significantly to the left and erections are painful when I get sexually excited. I have lost length and girth. As a result my sex life is nonexistant. I have two questions: 1. Could the cath used during my surgery, or the sugery itself caused my PD? Remember I had no problems till then. 2. Do you think accupuncture or some other type of nonsurgical procedure could help me?

While there is no likely relation to the back surgery, catheters can precipitate PD. I doubt acupuncture will help this. MG

Have I gone so long with celibacy, that I won't work again?

One of the challenges with PD is to remain sexually active - long periods of abstinence can reduce erectile function. MG

I am 63 years old, have had PD for over 4 years and my penis curves upwards about 30-40 degrees. My wife finds sex to be uncomfortable and so we do not have sex anymore. I have done the verapamil ointment and the injections twice. Neither treatment improved the situation. I saw a post from several months ago about someone considering acupuncture. I did that earlier this year, two treatments a week for two months with no improvement. I have not done the Vitamin E before. Is there any reason to start doing it now?

With PD of 4 years duration, it is unlikely that vitamin E will reverse the bend, but there would be no harm in trying it (400 units daily) for six months or so. MG

 

 

November 2008

my boyfriend suspects that he has PD. Nothing has been said between us until the other day when my OB asked me why I wasn't sexually active given my age of 45. My boyfriend is 57 and had a history of depression. We started going out for almost 4 years now. In the beginning of our relationship, I noticed that the shape of his penis is like a banana, really curving downward towards his anus. I haven't seen one like this before but I've heard it is congenitally normal, so I did not pay much attention to it. However during our sexual intercourse, his penis comes out a lot due to this curviness and a lot of times I have to guide it with my hands so not to frustrate me. We rarely have sex ( 2-3 x a year) during the first 2 years and then according to him about a 1 1/2 years ago when we were having sex and his penis was not totally erect and I was on top of him and he felt a severe pain but did not tell me. Since then we have not have sex and have loss our intimacy and he tries to avoid the sex issue whenever I tried to hint him. I thought at his age he is beginning to have ED since believe it or not I haven't seen him ejaculate not even once! The pain went away after several months but he noticed a sharp angulation to the left ( 45 degrees) even if it is in flaccid state. I told him to seek medical advice but he is embarrassed of obvious disfigurement not to mention taking pictures of his penis in an erect state which we both know is emotionally distressing. This has really undermined our intimacy and relationship. Can that incident of mechanical force create a scar tissue that can lead to PD?

That type of incident can definitely cause PD. Perhaps if you accompanied him on the first visit for "moral support", he would be willing to see a doctor. MG

In the surgical procedure to correct Peyronies' curvature, tissue identified as "temporalis fascia" is used in the process. Where is this tissue found? Is it taken from the patient? I am considering surgery as a corrective action

Temporalis fascia covers the muscle above and in front of the ear, the one that moves when you chew. It is an excellent graft material and works well in the repair of PD. MG

I have slight indentation on the right side of my penis when erect and was diagnosed with PD. I have a strong sex drive and firm erections and am not even 40... I am in the early phases, one month- Also, I'm starting VERAPAMIL gel this week as well as vitiman E. Was wondering what the proper dose would be for that and I was wondering if masterbation was a bad idea. I am in slight but managable pain.

The gel is usually applied twice daily. Masturbation is not harmful to PD. MG

I am twenty-four years old. I started noticing an erectile curvature in the spring of 2007. Since then the rightward curvature has increased but stabilized. I've seen a urologist who diagnosed me with PD and prescribed me Vitamin E, but the vitamin has had no obvious effect. My wife and I have noticed a marked loss in interest in sex on my part. When we do have sex, I am worried that we will do something that will cause me pain. That, I think, is the reason for my lack of interest. But recently, I have begun to notice a reduction in rigidity, which makes sex even more precarious. Not only that, I've noticed a lack of interest in other areas of my life (e.g. school, hobbies, etc.) which I've suspected was related. I'm sure part of my problem is psychological, but how does one overcome it? My urologist said I have only a "slight to moderate" bend to the right. The bend occurs at the base of the penis, and there is a noticeable bulge of tissue (plaque, I suppose) at the base on the left side. When erect, I cannot push down on my penis without pain. I can straighten it, but if I push any further to the left I experience great pain. And too great a stress on the shaft from straight ahead causes me significant pain at the base on the left side, and it feels like here it is trying to move to the left slightly. When I contract my muscles, too, the base moves slightly to the left. Is all this normal for PD? Does PD effect in any way the penis's anchor to the pelvic bone?

Psychological or emotional effects often complicate PD - and they tend to resolve as the process stabilizes. Plaques close to the body can affect the way the penis is anchored to the pelvic bones. MG

I was recently diagnosed with PD after noticing a lump two months ago. It could have been related to trauma from about 5 months ago. My urologist prescribed 400 units of vitamin E twice daily which I just started today. Within the last three or four weeks, I've experienced a buckling or hinging at the location of the plaque which is on the left side and a little on the top near the base of my penis. My penis is not even bending, but I have some indentation where the plaque is located. It's very slight and doesn't bother me. I have a few questions for you... 1) What are the chances (percentage) that the buckling will go away on its own just from taking vitamin E? I'm 35 years old. 2) My doctor gave me samples of Viagra just in case. Can this help with the buckling at all? I am still able to have intercourse with my wife, but I have to hold the area during initial penetration to keep it from buckling. 3) My orgasms don't seem to be as strong recently. Is that a symptom of PD or is it just in my head?

Buckling will usually resolve as the diameter restriction improves - though Viagra can help in the interim. PD does not directly affect orgasms, unless you have painful erections in which case they are temporarily inhibited. MG

I am fifty three years old and have diagnosed PD since age 40. It occurred within about a week after I had a vasectomy, during which the doctor seemed to be inordinately rough during the procedure. About five years ago I saw a site on the internet advertising a "male health clinic" in Toronto, Canada, offering shock-wave therapy. It showed a photograph of a multi-storied building that I assumed was the clinic itself. Having been told of the dangers of surgery and having tried several other topical treatments, I signed up and journeyed to Toronto. When I got there, I found out that the "men's sexual clinic" was not the building itself, but only a small, rather shabby office located within the building. The owner of the clinic, who had sounded so sympathetic on the phone, was not a doctor or even any type of medical professional. There was a waiting room, and when you entered the small treatment area there was actually a bedsheet hanging on a line that closed off the ultra-sound machine, or whatever it was, treatment area. This raised some red flags, but since I was there and had already invested several thousand dollars in treatment fees, hotel bills and airline tickets, I went ahead. A doctor that apparently was a contracted medical student did the treatment. During my first treatment, he had another young man that he was training to do the procedure that had never done it before...I was his first patient. I was told that the young man in training would be doing my second and third treatments, which I had already paid for. I balked at that and told them that I would not accept this, and that the I wanted someone who at least knew what he was doing to complete the three treatments, which did happen. Well, after these treatments and spending a few thousand bucks I went back to Oklahoma with no results. The internet site had said that I would be followed up with for a report that this "clinic" would be making to some sort of professional medical council. Of course, I never heard from them. I just wanted to write this to caution my fellow PD sufferers to exercise caution in these matters. Since there is no really effective treatment for PD, and we all get very frustrated because of this. we are vulnerable to the offerings of people trying to hold themselves out as something they are not. I have read that ultra-sound treatments have been effective for other people. Are there any doctors in the Oklahoma area, or close-by states that offer this treatment from bonafide doctors?

Thank you for this report. Scientific data does not support the use of shock wave therapy (lithotripsy) in the treatment of PD. Ultrasound has been used for years, but has never been proven effective in double blind studies. MG

I have had PD for 10 years. I am 66. I can't recall any trauma but I started on a Beta Blocker around that time. I masturbate a lot and enjoy having erections and feeling complete. My curvature isn't that bad although I can't say how many degrees. I use Cialis on a regular basis and I am able to have intercourse without difficulty however I find my length has reduced over the years. When using Caverject injections I maintain a strong erection without any pain. I use between 10 and 20ug. What I would find helpful in judging curvature would be photos of real cases. Is there any chance in this digital age of getting photos on to this Forums?

Perhaps in the future I can post (anonymous) pictures. MG

I am 49 years old and recently diagnosed with an early stage of PD based on pain I was experiencing (but no noticeable curvature). My urologist prescribed a combination of Potaba, ACL and Vitamin E which I have taken for about a month. (The Potaba has not done wonders for my stomach but I am tolerating it.) The pain has decreased somewhat. This week I saw another urologist who is recognized as an expert in PD. He also believed that I had an early stage of PD but wanted to immediately put me on a combination of Trental, L-Arginine (1 gram) and Viagra (50 mg). He did not think that Potaba was helpful, but I could continue with it if I wanted. I feel awkward calling my first urologist about the other doctor's recommendation. Also, I am very reluctant to take Viagra on a daily basis. I checked with my primary physician and he had some concerns about that as well. I have read that Trental has had some beneficial effects for PD, and even my first urologist told me it was an option (along with the Potaba/ACL treatment) although he had reservations because some people had side effects from it. Have you heard of any experience with the Trental, L-Arginine/Viagra treatment? If so, does it makes sense to change the course of treatment after a month, or does it make moer sense to add Trental and/or L-Arginine as part of the current treatment. Finally, have you heard of Viagra (or similar ED medications) being used for PD and are you aware of any risks from using Viagra on a daily basis? Finally, both urologists think that I may also have BPH (some incontience, weak stream in the morning) but want to deal with the PD first. Is there any relationship between PD and urinary/prostate problems?

Many urologists are using a similar combination of trental, L-argenine and one of the erection drugs like viagra - they all seem to have an anti-scarring effect, though there is no good clinical trial data on this yet. There is no relationship between PD and prostate problems. MG

I am 46 years old, about 3 months ago I had pain in my penis when erect, almost like it was bruised. The pain went away but now I have a "dent" and bend to my penis on the left side. I also seem to have lost length and girth. Should I see an Urologist? If yes can they help or can I go on like this?

It would probably be a good idea to see a urologist, in the interest of stabilizing the situation so it doesn't get any worse. MG

I was diagnosed with MS about 4 years ago. I use Interfeon theapy and recently have developed Peronies.

Intereferon is currently used to treat PD - I am not aware it precipitating this problem. MG

 

October 2008

I am 57 and developed PD after a prolonged illness, almost 9 months, and severe weight loss, 60 pounds in two months, and severe muscle break down of muscle tissue, very high creatinine levels, and kidney failures with severe dehydration. I have fully recovered....yeah!! Mine developed as a hard curve to the left and thining of the base of the shaft on both sides. Went to a urologist and he confirmed the PD and also prescribed the use of a vacuum pump. To my surprise after two months of regular use the pump eliminated the curve as well as increasing the blood flow. Yes it tends to be a bit erotic but THIS IS A GOOD THING. It aso removed most of the pain involved. I still get some discomfort when things get "cold" and the tissue compresses. I've done alot of reading on the subject and I can only say that it really does have a great deal of effect on PD and the curvature.

Vacuum pumps can be helpful in managing PD - thanks for the report. MG

49 year old man about 6months ago i noticed my that my penis was starting to bend to the left i have some hard lumps along the shaft of my penis and i cant get a full erection i am a diabetic so i am not sure if this as anything to do with my diabetes

PD is somewhat more common in diabetics, though not as common as erectile dysfunction. MG

I'm 22 and my penis has had a slight (probably about 30 like other people have posted) curve upward as long as I could remember. I don't have any pain with erections or during sex. Is this peyronies? If so, can I just pick up vitamin e pills without a prescription to cure this? If not, is there a a way to cure this curve anyway? Medications will not cure congenital curvature. Usually surgery is required, but if the bend is minimal, stretching devices may help. MG Is there anyway that a penis pump could help with Peyronies? Yes, see the response in the previous month. MG Mine started after the 3rd of 3 TURPS or Transurethral Resections of the Prostate. Any statistics on how common this is for TURP patients to develop? I head somewhere it (Peyronie's Disease) was 16 times more likely after a TURP.

I'm not sure about the factor 16, but PD is definitely more common after endoscopy of the urethra. MG

I would like to send some pictures of my problem for a professional/doctor to give me an opinion on what problem I have, and how I can fix it(without surgery). I did write a very long message previous to this, and so I'd appreciate a reply and helpful information. note that as i still live at home and am not independent I will not go to a doctor anytime soon, so spare me the "a doctors the only way".

Perhaps one of the Doctors in your area can help. (see links or forum entries for referral sites) MG

i "broke" my penis while having sex. in the heat of the moment i "missed" the vagina and slammed my penis into the area between her vagina and anus. about a month went by and i noticed that my erections had a curve to them. i immediately went to the doctor and he told me it was o.k. painful erections? sometimes. able to have sex still? yes. he then said i should be fine; no need for surgery; be on my way. now, a year and a half later i was having sex and (not sure what happened) but in the middle of it something happened and it became very painful. a day later i had a bruised penis and there is a bulging vein the can be clearly seen when erect. it is painful to touch. i wanted to inspect my penis while erect so i masturbated and every time my hand went to the base of the shaft and touched upon the vein it was painful. i have all symptoms of peyronie's- curvature, painful erections (not so much anymore) and shortening. a year and a half has gone since the initial 'break'. what can i do now? im of course concerned with the pain, but the shortening is of great concern as well. will/can the length be restored?

This sounds like PD, which can be brought on by sexual trauma. It is difficult to restore the length lost to this process. MG

 

September 2008

I’m 60 years old and have had PD for 6 years. It started with an accident. I fell over a chair and caught the top rail in the groin. I have been treated by urologists locally and at Mayo. Basic answer is if you’re still capable of having sex forget about any other treatment. My doctor at Mayo prescribed Viagra so I don’t think there is an issue with PD patients taking it. The do nothing approach does very little to overcome the mental aspects of the disease. Today there are numerous procedures done with a scope. Has anyone attempted to remove the scar tissue in this manner?

No, this approach has not been used in PD surgery. MG

I'm 39 years old and happily married. About 2 years ago, I started noticing a change in my penis. Mines different, it's smaller at the base and bigger at the head. About half way, I noticed 2 knots, on each side, left and right. It's straight, but because of the base not increasing during an erection, it's not as long as it was. Just had a physical and in good health, except my cholesterol is high. Been considering going to a urologist, but so expensive. My question is, do I have Peyronie's Disease and how did I get it? What can I do to break up the Plaque? I've read that sometimes it can go away on it's own.

This sounds like PD to me. In most cases we are unable to find a cause. It may resolve on vitamin E at 400 units per day. MG

tengo 18 años.. y creo tener este problema, ya que mi pene erecto presenta una curva importante hacia abajo, como la imagen de wikipedia aproximadamente.. Me gustaria saber que tengo que hacer, y si puede que no se trate de esta enfermedad, y que sea otra cosa.

You have congenital curvature, not Peyronies. An operation can fix it. MG

I was diagnosed with Peyronies disease about 9 months ago. The bending occurred almost at once, not over a period of time. I do not have pain with an erection, but do not recall whether or not I had some pain at the time the condition first presented itself. My concerns are this: The indention is on the left side, more towards the underside of my penis, about 1 ½ inches long, starting from the base of the penis, resulting in a narrowing at the base. Is this an unusual location for the condition? Secondly, can I expect further extension and/or expansion of this indented area? What, if any, is the chance that PD may start to heal and the indentation becomes less prominent? Can any of the medications I am taking have adverse effects on Peyronies.

Expansion of this area is unlikely. I would recommend you get off of atenolol, as beta blockers may aggravate PD. MG

I understand clinical trials are starting. Is it possible to participate? Dr. Lue says it is the only medication which he is receptive to. Do you have a viewpoint and do your readers have experience/success rates with other medication? I am now taking pentoxifylline 400 mg; 3x per day. I take 400 units of vitamin E also. Is there any evidence that mega doses are helpful? I have a double curvature (down and then to the right)and a band of reduced erection half way down my penis.

Preliminary (phase IIb) Collagenase clinical trials have started, but at this point are fully subscribed. If and when further studies create more openings, I will post a notice on this site. Mega doses are not helpful. MG

about three years ago- i noticed that my penis seemed to be "broken" bending to the left when erect about an inch down from the top- i went to a urologist- but when flacid he couldn't tell (he was gruff and not cool anyway- so i didn't feel he was helpful) he suggested l- carnitine- I am bummed because i feel my penis (which used to be big and straight) got smaller and is bent- is there someone i can see- something i can do?

You need to see a urologist with an interest in this condition. Try referral guide in http://www.peyroniesassoc.org or http://www.ImpotenceSpecialists.com. MG

any thoughts using the stretching of the penis device like fastsize?? have there been positive results?

Early studies suggest they may be helpful. MG

I am 52 years old and have a healthy sex life...for a 52 year old. However the last several times my wife and I had sex it did not feel like I had become as erect as "normal". I just shrugged it off to being tired and getting older. The other evening I used a condom (we were going out) and I noticed a distinct lump or mass on the left side of my penis just below the head. It looked almost like a small varicose vein, but it was hard. There was some mild pain associated with intercourse and when I was washing up I could feel what could be described as almost a small string of pearls running along the top of my penis then wrapping to the left under the head. I immediately thought that God had cursed me with Penis Cancer or something equally horrible, so I Googled the problem and found your site. There is some mild pain associated with touching the area which eventually fades if I don't touch it of course. So several questions: Does this sound like PD?

No, this sounds like Mondor's syndrome, which is a temporary benign condtion involving clots in the superficial penile veins. Have a urologist check you. MG

At 51 years of age, the symptoms as described have come on quite quickly. I noticed the feel of plaque a few months ago (almost like cords in a whiplash neck muscle, except quite distinct: I can feel the actual sites along the left side of the shaft, and thy are like beads in the form of squares on their sides)...the penis, when erect, bends incredibly to the left and appears thinner, almost emaciated but certainly still workable...some distracting pain, but nowhere near severe... The funny thing was that I went to the hospital...had x-rays and sound wave "x-rays"...despite my direction to the site they dismissed it and looked elsewhere, missing the whole thing altogether... I will begin the vitamin e and see how it goes... As for the curvature which is very acute, I'm marketing it as a really unique experience...make a positive of it all is best I think...as such, we should call it Peyronies condition, not a disease !!!

I agree, it is not really a "disease". MG

For the past four months I have been experiencing painful erections, which increase with the degree of firmness of the erection. The pain seems to be coming from within the penis, behind or near the glans. On palpitation in the flaccid state, I can feel a very very small ridged area about one inch behind the glans. It is not especially painful. During erection, there's a slight elevation, a kind of line I'd call it, extending in front of and behind this point. When erect, this area becomes somewhat more painful, or tender. I also notice that it is harder under there than on the bottom, and the hard area feels closer to the surface than on the bottom. I have had some problem with an inflamed or swollen vein on my glans, which has subsided somewhat over the past few months and which was also painful, but this area seems very distinct from that. I am 59. Does this sound at all like it could be Peyronie's?

Perhaps, though this could also be Mondor's (see above). MG

I recently contracted a sudden onset of peyronies as a result of treatment for kidney stones involving urethral catherization and cycstoscopy. I am attempting to determine whether the physician utilized adequate care and diligence in the procedure. I have significat internal scarring which is manfested by several hard lump seven when not erect. It is apparent to me my case is rather severe as I often experience pain when not erect. I am totally unable to have sexual relations. The onset occurred almost immediately after the medical procedure. I am considering legal action. Is peyronies typical after such procedures?

Urethral instrumentation can cause PD. MG

I'm 32 and recently woke up with pretty intense pain in my penis. After months of STD screens (all negative) and courses of various antibiotics (without effect), my third dermatologist noticed a very small (about half the size of a pea) lump in the right side of my penis near the urethra just below the head. A urologist thought it may be PD. The lump causes a sharp stinging pain which fluctuates from mild to fairly intense. The pain doesn't seem to get worse (or better) with erection or sexual activity. There is no distortion of my penis or reduction in my ability to get and stay erect. 1) Does this sound like PD to you?

No. MG

Is there anyone who has ever been cured? I have had it for two years in feburary. I have been through Varapmil injections with the pnis stretching thrapy and the curve is now more pronounced and I think the traction tharapy has made it worse. I have not neutropol. Seems that you have the same line about it anyone that knows says. I am hopping to be able to try the cologenase injections. As of June I was not a candidate for the trials that were ending. I have 2 injury sites one on the left and one on the rite. It really is breaking me inside. I my wife and want a divorce. I also blame myself and am wanting to die. I now live with the greatest fear I never knew existed. Pain when ever I am aroused. I just have no one to talk to. My Dr. is a uroligist so this is not his concern. He is busy trying to to figure out how to cure this disease. My wife dosen't care it is not her problem. Plus she had kids so if her femininity is damaged she dosent care about mine. It sucks eveymorning waking up to pain in my penis from my usual morning erection.Just has anyone ever been cured?

It is possible to fully recover sexual function lost to PD, though after 2 years this disorder can cause permanent and irreversible changes in the elasticity of certain regions of the erectile mechanism. MG

I am 58 and have had PD for about 9 to 10 years now. It started off with blood coming in my urine and slowly there was a loss of sexual activity. Probably I do remember my wife violently sitting on me and my penis started paining. The blood continued for over two years, but not every time I urinated. Then I noticed calcification as three lumps developed at the base of my penis. I met a doctor friend who advise a scan, which I went through and three clear calcified lumps exist at the base of my penis. At this point the penis circumference had reduced and the length of my penis has decreased from almost nine inches during my university days to a mere five inches now. I met a specialist who prescribed harmone tests. My testosterone level was almost zero. So her prescribed medicine and it rose to 5. My this time my penis was bending upwards and the pain has gone. Now I can have normal intercourse with my wife, but the frequency is about one a month. Sometimes when we are on holidays, we have intercourse twice a day and even for two or three days running. I know the ‘glory of old’ cannot return, bu I am convinced I can enjoy my sex to the full with some assistance on how to proceed

Sounds like you had a penile fracture. If your testosterone was that low, you'll need to continue on hormone replacement. MG

I am 34 years old and I realized that I had PD a little more than a year ago. It started out as a simple bump near the top and a few months later developed the curve and eventually moved down the shaft. It seemed to me that I was fortunate to have the curvature just be an exaggeration of the normal bend, so it did not effect my sex life drastically. Now it seems the main issues that I have are the length and thickness have reduced dramatically. The very low base portion is thick as it once was, and the remaining 90% is simply a resized version of what I once had with a bit more arch. Firmness during intercourse is not a problem at all. It may be crazy, but would something like an enlarger/pump improve circulation to increase size?

Vacuum pumps can be helpful in improving expansion in men with PD. MG

I am 25 years old and recently (3 days ago) injured my penis due to jelqing for the first time. I will never, ever, do this again. I immediatly after completing the session had sore discomfort, especially bilaterally just above the ring in the middle of my penis. I also noticed a wrinkling of the skin there, as if the area retracted slighty inward (less noticable when slightly flacid, but still appears strange). These areas feel very stiff and painful under the skin without an erection. I have not tried getting an erection since the incident, and started taking vitamin E. I saw an emergency room doctor and am scheduled to see a urologist, as the ER doctor said this was overuse, and I should use ice, refrain from trying sexual activity, and see a urologist if the pain persists. I have the following questions: should I use Ice? Would light stretching while not errect be a good idea? When would trying to induce an errection be permitable, or should I rest as long as possible?

Ice would only be helpful in the first 12 - 24 hours. I think rest without stretching or erection for 7 -10 days would help. MG

I have a curved penis that points downwards. Seems to have always been this way since I can remember having erections. I don't have painful erections, but it is difficult to perform certain positions. It is very difficult to do it from behind due to the way it curves, which is a drag cause that is how my girlfriend likes it the best. I recently was reading about some treatment for that in which there is a cream that is used and can have straightening results within about 6 months or so. How do I know if mine is just a normal bend or if I have peyronies? I don't really feel any scar tissue per se, but that build up should be inside the penis, right? How does one tell if it is normal or peyronies?

This is not PD, but congenital curvature - it will not respond to medications, but can be corrected with an outpatient surgical procedure (Nesbit). MG

I'm 61 years old and noticed several of the symptoms mentioned in the posts, including a venous fibrous dense lump near the head of my penis..been there for one-two months and causes pain in an erection. Recently, last two attempts at intercourse failed..either the erection goes away or perhaps the pain is a de-motivator. There is no really obvious curvature. I have taken Levitra for 4-5 years due to erection difficulty. Also, I have Deptryens (spelling?) in both my wrists..my Dad also has this so I probably inherited...and read that there's a connection. Could this be early stage PD? Will it go away eventually? Would Vitamin E 400 IUs help? I read a Google ad about Neprinol..a kind of collagen dissolving agent..is this for real or an unproven come-on? Have not seen my doc yet on this. Any comment would be appreciated.

There is a genetic component here, with the family history of Dupuytren's. That makes your condition less likely to resolve spontaneously. While there is no placebo controlled data on Neprinol, there is anecdotal evidence that it can help. MG

 

August 2008

For years you have referred to clinical trials underway for treatments such as collagenase. However, you've never mentioned the results of these trials - just that they are ongoing. Why don't you give some details on the results of the trials or list sites where results may be obtained? Be specific - where are the trials taking place, how many participants are there, is it possible for men to participate, etc. You are entirely too vague. Surely, some of these trials you've referred to in the past have concluded.

The current trials are showing promise, but since they are being conducted by Auxilium Pharmaceuticals Inc. (a drug company), all investigators are under a confidentiality agreement not to disclose specific data or results until the study is published in a peer reviewed journal. The last published study (by Dr. Gerald Jordan) appeared in the Journal of Sexual Medicine in 2007. MG

I'm a married man, 47 years old. I was diagnosed with Peyronie's disease 10 - 11 months ago. Initial symptom was a hard little lump -much smaller than a green pea- around 1/3 penis length from its base. I consulted and urologist within a week or so and by examination (touching) gave his diagnosis. He prescribed colchicin and vitamin E; because I have digestive problems I took only the vitamin E and sought homeopathic treatment, which I initiated. After two months a second lump developed and I started feeling pain when my erected penis was pressured, for instance against my bed. I had no pain during intercourse. Doctor suggested a new treatment consisting in injections directly on the affected areas. He would attend a seminar where the procedure was to be presented. I have not seen the doctor since then, and I didn't tell him I was not taking colchicin. Things were pretty stable until in mid June (8 - 9 months after diagnosis) I noticed my penis curved upward during erection. When it was flaccid the two little lumps felt the same but in the recent days (early August) I have noticed something like a hard cord or very thing plaque, perhaps ending in one or both lumps. I still can have intercourse with no pain, but feel a little bit inhibited to have sex. Another doctor suggested I resumed taking vitamin E and started taking PABA (is it the same than POTABA?). What would you suggest as a next step? How can I assess my penis' curvature in degrees?

A course of Potaba would be reasonable, though I have not seen many responses to this drug. Make a tracing of the erection then use a protractor to measure the angle. MG

Recently I noticed a curvature to the left of my penis. No pain, erection is ok. There is shortening. I am embarrased to go to the Urologist. I would take care myself. Is Verapamil cream Potaba and Vitamin E are available OTC?

Only Vitamin E. MG

About 2 months ago I woke up with pain and a noticeable contortion at the tip of my penis. There seems to be some sort of scar tissue forming under the head which is drawing the tip downward during erection. It came on rather suddenly, although I don't remember being injured. Could this be Peronnies? I saw a urologist and he said there was nothing I could do except surgery to correct this problem. It just seems to me that something that came on so rapidly could be so permanent. Out of desperation, I started taking Neprinol. It's only been 4 days now, and I was wondering if anyone has had any luck with this product?,, and is there anything else out there that may work before going under the knife?

Neprinol is one of many therapies that are safe but unproven. Most PD patients will never need surgery. MG

I am 63. My urologist has diagnosed me with PD. Very painful when erect and noticeable hardening areas at sides and top of shaft. He is starting me on verapamil injections in two weeks. My question is: what is the prognosis with verapamil and what are the risks?

Risks are mainly discomfort & bruising. It helps approximately 65 - 70% of the time. MG

I am 40 years old and have had an indentation on the right side of my penis for a few weeks now(causing an a partial hour glass). It is about an inch from the base. It does not cause any pain and I can still achieve a erection. I am healthy but I have had a little loss in firmness in my erections for about 1 to 2 years. I also take propecia for hair loss. I am not sure of what I should do next. Should I consult a physician or should I take a wait and see approach?

I would see a urologist. MG

I am 29 years old about 11 days ago I noticed my penis was bent with a dent near the bottom, it now bends to the side after researching the web I have determined it is most likely pd, there is a hard bumb near the dent, I was wondering since it is still early are there any measures I can take to limit the severity also is there a chance that more then one curve will form it appears another may be forming near the top right, and it also apears to have a bb sized bump forming too, what should I do and are more then one curves common.

Start on vitamin E 400 units per day, and see a urologist. MG

If it's all right, I'd like to get an clarification of the term * Peyronies Disease* When a person accidently but seriously injures themselves on or in the penis leaving a bend or curve especially during sexual intercourse, why is that injury referred to as a *disease* I can understand why it would be classified as a disease if it happened naturally. Last year I wrote in about my problem that developed because of improper use of a constriction ring during intercourse. Basically, I didn't take it off quickly enough ( just before ejaculation). The ring was being used because a certain medication ( Advair Inhaler for Asthma) that I was using caused me to lose my erection mid way through sexual activity. I was told that things like that could happen with that medication as well as other similar medications. The constriction ring was used to help my penis stay rigid. The next day after this accident I had serious black and blue bruising on the side of my penis which ran the length of my penis and as it healed over a period of one month I was left with a curvature that had never been there before. I was told that the only possible corrections to this problem would be to try out all of the different methods that are spoken about on this forum, yet it was still catagorized as Peyronies Disease. I then tried the different suggestions mentioned short of surgery and injections. Nothing helped and to this day erections are somewhat painful which has forced me to have less sexual contact with my wife. An example--If a person accidently breaks a leg and is left with a permanent limp it's not referred to as a disease.

You are correct, "disease" is a poor choice of words. MG

I’m 48 and exhibit all the symptoms of PD for the last few months. I’m taking Vitamin E and hoping that this resolves itself as neither the pain nor the bending are severe at this point. Will sexual activity (intercourse and masturbation) exacerbate the situation or is it okay to continue this on a normal (i.e. relatively frequent) basis?

There is no reason to avoid sexual activity. MG

I am 22. My erect penis has a 30 degrees curvature to the right and 20 degrees (roughly) upwards. It first appeared when I was 18, in the beginning it was bent 90 degrees, no less. I cannot remember any trauma that could have caused it, nor dit it developed gradually, in fact it emerged "over the night". The following weeks it gradually regressed to the present 30 degrees bent. Is this PD ?

Sound more like a variation of congenital curvature. MG

I am currently 40 yrs old. Approx 4yrs ago I was in a severe car accident that left me temporarly on life support due to many fractures and injuries . One of them being a badly broken pelvis. About a year after my accident I notice pain in my erections and during intercourse. I have no troubles getting erect or ejaculating. I have noticed however , a change in the size of my penis . I have lost length and girth . I now have an hour glass shaped or bottlenecked penis just below the head, After reading on line , I'm positive I have PD. After leaving it this long , am I going to be able to do anything to reverse or stop further damage?

I doubt further damage is likely at this time - reversal of the deformity will be a challenge, however. Best to see a urologist. MG

I am 35 year old, male, living in India. Almost 6 months back, i started having pain in my penis while having erection. No problem when the penis was flaccid. I had no other problem and sex life was OK. But almost 3 months back (in April 2008), while having sex, my penis got pushed on the worng side during erection and there was a small sound. Within next few days i noticed, that my penis has become crooked, while erect. While erect, earlier the tip of the penis used ot be towards the sky. But now on erection, i notice that at one point it suddenly bents inwards towards stomach. So it become something like "J' shaped. I continued to have the pain while erection. Currently the pain has reduced and only if i try to bend the penis in the opposite direction, do i get the pain. Penetration during sex is difficult, but managable. I went to see a Urologist who got the scan and the Xray done (assuming it to be Pyronie's disease). But in the scan as well as Xray, there was no indication of plaque calcification. He now wants to himself see my erect penis by giving some injection, before coming to any conclusion. He may probably call me for this procedure, in next 7-10 days My rigidity, girth and the size of the penis has reduced. I also feel that it does not get erect as easily as it used to earlier. I feel that i have Pyronie's disease.. Whats your conclusion? What do you think could have happened? What do you think should be the medication for this?

This does sound like PD. Discuss the medications available to your Doctor - there are many possibilities. MG

I believe I have P.D. because about 4 to 6 months ago I noticed a 90 degree upward bend in my erection about two thirds of the way down the shaft towards the head. I have no pain, can find no hard tissue, and don’t recall any trauma to the penis. This bend seemed to appear overnight. I’ve seen a urologist who seems perplexed that we can find no hard tissue in the penis. I’m taking 400 IU of vitamin E daily and the urologist wants to use a 15% verapamil gel. Originally I thought this condition might be caused by frequent masturbation and I tried manually bending the penis in the opposite direction. Then I read that bending the penis might only worsen the problem so I stopped that. Now I read in your forum that some are trying the manual bending technique. Would trying to bend the erection in the opposite direction worsen the problem? Or could it help?

Early data shows streching / traction devices may help, though there is much to be learned about these techniques. MG

Why not admit that like most terminal cancer,there is no cure and stop giving patients false hope? I am 55 ,diagnosed a year ago. The first urologist,while I despised him because he admitted there is no hope and said I was depressed and to deal with it.Cold but true. I refused to give up,researched Peyronie's at the hospital medical library where I worked as well as internet info. I asked my PCP for an auth for a second opinion. The second urologist now gives me more hope,basically because my PCP called him and said I was a friend as well and he has known no one who was more sexually prodigious(close to 1,000 women in 35 years). The second doctor prescribed 8000 mg of Potaba and 20% Verapamil topical b.i.d..I also purchased on my own a vacuum penis pump in a vain attempt to break up the plaque. I have been celibate for more than a year, have no libido,have major depression often with suicidal ideation. I have been seeing a therapist for help. My self identity has been so closely linked to my sexuality, I have not been intimate with my wife,am ashamed to show my self to her(she has no idea about this) and there is not a day that passes that I do not think about my disfigurement,and loss of almost half of length.It is extremely distressing. I find myself drinking more,taking sleeping meds and benzos just to cope with a loss that is on par with a family death or job loss(which I have just experienced).Life can be cruel. My PCP, tries to minimize my situation by telling me he has to tell people they are going to die everyday. Somehow that does not make me feel better about my situation. Right now I am doing my best day to day,taking anti-depressant medication as well as the regimen I read has minimal if any effect. I am seaching for a new raison d'etre. My despair is turning to hopelessness. Thank you for your compassion and this forum.

You are welcome - I hope information herein is helpful in some way. MG

 

July 2008

I am 34. Six months ago I noticed a hard lump in my penis. It can be felt, but is not visible on the surface. When the penis is erect, it is slightly indented on both sides. There is no pain and no curvature. I have been told it is PD and that within a year this long irregularly shaped lump will disappear. Is it likely to disappear really?

In your age group, spontaneous resolution is likely, particularly since over 6 months you have developed relatively little deformity. MG

I am 58 years old and recently experienced a sudden curve of about 30º to the left and about 2 inches from the base of the penis. I have no pain, no plaque or any other symptoms that seem to be associated with the disease. I initially thought that the curve had developed due to regular masturbation (I am right handed) but was curious enough to do an internet search and therefore found your site. I have not yet seen my family doctor. My wife has not noticed as we rarely have sexual relations, but the condition does not seem to interfere in any way. I hoped that the curve was from the masturbation because that is something I could control. Within the last 2 years I have begun taking Lisinopril for mild blood pressure elevation and Lipitor for cholesterol. I also take alegra for allergies. I also tried viagra just prior to the onset of this curvature. Is there any possibility that this is not Peyronies, or that drug combination may have caused/contributed to these symptoms? Thank you for your web site, it helps to know there are others who have this problem and that mine is a mild case by comparison.

I don' think this is drug related - nor does it appear to threaten your activities or functional level. MG

I am facing sex problem almost 8 years. I am 27 year old unmarried man. 8 years before i done sex with boy. after this homosexual, pain had been start on my penis. I taken medicine, pain stop but often i have night fall and bottom side of my penis is very week. after that i also tried of sex with girl but i discharge early. if i eat some hot things like fish, egg, again pain start in penis. on every night fall i awake due to pain. I can't sleep after nightfall until i does not go to bath room. after erection my penis look very week and it bend to down side. I am very worried because after few months i am going for marriage. Can you please tell me Is it normal or these are the symptoms of PD.

These symptoms do not sound like PD. MG

I've been less and less interested in sex. I now think its because of the mind trip I've been on because of this problem. I used to be a proper size when erect but I've woken up in the morning with erections of 4 inches when I remember measuring twice that when younger. I attributed this to the fact that people say you shrink with age but this is ridiculous. I've tried the wait see, it'll fix itself method but it hasn't really corrected itself. I can have sex. Its not bent in any direction now, it just has shortened length and girth and the hourglass shape. I think this comes and goes because I felt it was better at one point, but that might have been wishful thinking. My wife has only recently noticed the hourglass shape (since I've had little to no interest in sex apart from quick masturbation by myself for easily 6-9 months) and wants me to get to a doctor NOW.

Your wife has the right idea - sorry but I don't know anyone in your area (Japan). MG

I am 31 years old and have a penis that curves to the left while erect. A new girlfriend was concerned that it may be related to Peyronie's Disease. I have told her that it has been that way since puberty. I feel this is probably a result of tighter clothing during puberty (tightly whities). I also noted that I have not had any discomfort during intercourse; she noted that it was not an issue for her - she was concerned for my health. I searched the web and tried to do a self examination (but of course I’m not doctor). I could not feel any areas on the penis that felt like there was a build up. Should I see a Urologist to confirm that it is not Peyronie’s Disease? Also would any Urologist be able to diagnose the problem or are there specialists?

If this curvature presents no problems to your girlfriend or yourself, I wouldn't worry about it. Some penises are not completely straight. MG

I got peyronies disease on one night of sex while using Viagra. If there was any sign of it before that, I didn't know it. I had sex that night and could feel my penis bending but just thought that the Viagra wasn't all that effective. The next time I got an erection, I saw that my penis was severely bent to one side. I have since been to a urologist who diagnosed me with peyronies. Is there any evidence that Viagra can cause this disease?

No, there is no evidence for that. MG

I'm a 37 yrs old, and I don't know what to make of my condition. I suffered some traumitization to the penis after hard sex late last August/early Sept. I noticed what was I thought was bruising on the bottom side of the penis, but the urologist didn't necessarily agree. That said, I was in severe pain for a few days, which then moderated. While I didn't lose any length or girth, I noticed that my penis now angles to the left more than it use to. I always had some curvature, and I noticed it doesn't curve that much more (perhaps a little). The penis itself is pretty straight, but it's not at 90 degrees with my pelvis anymore. The urologist said he felt some slight plaque build up on the right side at the base of the penis. During a follow up appointment, he then said he felt it on the left side, which would make a bit more sense. Needless to day, I'm getting a second opinion. When I feel around there, I don't feel anything quite frankly. I started using Verapamil 2x, and I was responding to it very well. Or just healing nicely. But prior to this I would feel better then relapse a bit, feel better, etc. I was getting stronger and stronger, and it was getting a bit straighter. One day was doing some stretches whereby I had my left leg crossed over the right when I felt something almost give. I regressed almost back to the original injury, but it's felling better three weeks later. I really notice the pain and sensitivity around the top most part at the base of the penis and down about 1/4 of the way, and I notice this sometimes after light masturbation. I also notice some discomfort about a few inches to the left and right of the bladder. There is no bleeding, no incontinence, and my prostate is ok. The physician also ruled out that I tore something, but I'm not convinced. And I'm not so sure this is PD. Does this sound like PD?

Yes this sounds like PD secondary to coital trauma - a common cause. MG

I am 30 years old and had a Nesbit procedure at the age of 20 to correct a severe lateral curvature that I had had since the age of around 14. The operation left me with a functional, though crooked and bent to a lesser degree, penis - as the constricted side of the penis remained so, and the other side developed two bumps over time, seemingly where the Nesbit procedure was performed. Surgery is not warranted by the curvature that I have now. However, I have read with interest about the reported effects of traction devices that are available, on the reduction of constricted tissues. I am wandering if it would be safe/wise to attempt a traction biased to the constricted side of my penis - in order to lengthen and de-constrict the shorter side having had a Nesbit procedure?

I think a trial of a traction device (such as fast size or andropenis) would be reasonable. MG

I HAD SURGERY TO CORRECT PEYRONIE'S 1 YEAR AGO. IT APPEARS THE CONDITION IS RETURNING TO THE SAME CURVATURE I EXPERIENCED PRIOR TO THE SURGERY. IS THIS POSSIBLE? AND IF IT IS IN FACT RETURNING WHAT ARE MY OPTIONS? THE SAME SURGERY AGAIN OR IMPLANT PROCEDURE?

It depends what surgery you had initially. I would reccommend a second opinion from someone who does a lot of PD cases. MG

I have had this condition for the last two years without being able to have sex not due to pain. I have no pain and I get an erection. The more erect the greater the bend. I calculated a 45 degree upward bend. I first went to my urologist about 6 months after I developed this condition. One of the group of doctors recommended vitamin e but did not specify the quantities. He also prescribed colchicine 0.6MG one a day and to see him in 6 months. I started on the medication but did not take them the 6 months as prescribed. When I went back to the same doctor he brought in the surgeon that works with the group. I showed them a picture of the curvature and he said that surgery would correct it. I told him I would think about it. Six months later I went in to the same clinic for a prostate check which was fine and the third doctor which is the oldest and my original urologist did the check up. I mentioned the Peyronies condition and what his opinion was for surgery. His reply was that he did not feel that it is a good way to go and that they have not had good results in his opinion. Now I don’t know which way to go or who to go to. Looking back I think this condition accured when I was having sex and we had a little incident where the penetration did not occur and the penus accidently bent back or upward causing a little pain at the time. I can still get an erection but the angle prohibits penetration due to the existing bend. I have lost faith in my doctors and am looking to find a solution I am 72 years old and have always been very active with sex and at this point of my life is causing me physiological discomforts not to mention my mate that is 30 years younger. If you could recommend the best doctor who is In my area or anyplace else.

I would recommend Dr. Greg Broderick in Jacksonville. MG

My husband was in an accident (head on - motorcycle -vs- pickup truck). He suffered a lot of bad bruising in his midsection from below breast to above knee. That was nearly 4 years ago. About one year ago, he found a small lump in his penis and we also started noticing a 'bend' in his erections. This bend is now pretty pronounced. The Urologist claims it is Erectile Dysfunction (ED). We disagree, as many of the symptoms are noted in the Peyronie's disease information we read, as opposed to the symptoms of "ED". Do you have any insight?

Sounds like PD to me. MG

I understand that the same laser treatment used for destoying kidney stones has been used to treat peyronies, it was stated that this laser and ultra sound treatment destroyes the calcium plaque that has gathered and caused the bending, If this is so, can you provide the name of the hospital or specialist that preforms this proceedure , thank you

Unfortunately these procedures are not effective. MG

Hi, my boyfriend is 24 yers old and four months ago started having problems with his penis. First he told me he didn't feel as well as before while having sex, particulary on the left side of his penis. We went to see an andrologist, who made to him an ultrasound not during the erection and afeter that he resolved my boyfriend was not soffering from PD as he was thinking. But even after that he continued suffering from a lack of feelings, a pain in his penis when it's not erect, difficulties to maintaining the erection ( even if not always) and a little increase of the bend of his penis that he have always had (to the left). So, a month and a half after, we went to see an urologist, who, after an other ultrasound ( this time during a driven erection), resolved that he was soffering from PD. Now my boyfriend has been taking VITAMINE E and doing ionoforesi for a month and a half and laser therapy for a month, but he's still suffering from a lack of feelings on the left side of his penis and difficulties to maintain the erection, especially when he is alone. The bend of his penis is increased to the left, but it's not more then 30 degree. I would like to know if there is a possibility to have an improvement of his feelings and erections after this medical therapys and if you think there is the possibility that the problems with the erections are caused by a psychological stress more that by the PD.

The onset of bending does suggest PD, though I think you are correct regarding a psychological cause for the erectile problem. MG

I had surgery to correct a congenital downward curvature and I've been OK for 14 years. A few months ago, after intercourse I felt e little pain and since then the penis has developed a slightly more pronounced curvature. Recently, during climax, I felt something "giving up" in the penis, with some pain, and now my penis hurts when erected and when touched and it looks a little more curved. Is it that what was stitched together 14 years ago has given up?

That sounds likely - I would see a urolgist for evaluation. MG

I am an 18 year old male. I have no trouble getting with females but I do have trouble explaining them something. My penis curves down at about a 30 degree angle. It has been like that since I remember and does not hurt during intercourse. I can see that it is quite rigid on the top. Do you have any idea of what this condition could be and if there are any ways to help or cure it. I have not consulted a physician at this moment but I may after I recieve this response.

This is congenital curvature, not PD - see a urologist. MG

I am 58 and somewhat suddenly (about 3 months ago) found my self with an exaggerated and consistent bend down and to the right about 3/4 out on my erection, while from that point to the head it remains somewhat soft. I also now have a sensation of discomfort (not quite painful) at the point of deflection. Historically, perhaps 12 years ago, I developed a small pea sized lump on the right side of my erection which disappeared about 5 years ago. At about that time (about 5 years ago) I developed an hour glass like condition as my erection was forming which would disappear once my erection was full but could remain if not thoroughly aroused. I recently asked my physician (an interist) about this condition explaining both the problematic angle and lack of firmness as well as my sensation of a subtle discomfort and thickening at the point of deflection. After his physical examination (feeling my penis between his fingers) he indicated he felt nothing.

This sounds like PD to me. MG

I have felt some pain at the top of my penis for about two months when I get an erection. There is no bending, hard/soft spots, or change in size. I am 31, have never had a real injury, but this pain comes and goes. Sex can be painful at first, but gets better after a few minutes. Do you think this is PD? I'm going to see a doc, but I'm trying to get an idea of what this is.

I doubt this is PD, though I agree with your plan to see a doctor. MG

Hello, I am a 26 years old. About a month ago I noticed that when I urinated it looked like my stream was going left. I got out a mirror to look at my penis closer and it looks like my head is slightly twisted clockwise. If I twist my penis straight I can urinate in a straight stream. Also when erect the head is still turned a little to the left but doesn't look as twisted as it does when flaccid. I can not find any plaques but my penis does look like it has a dent in one side and a lump in the opposite side like it is kinda shifted over. I don't remember any trauma, I had a std test with a swab 4 years ago and a year ago and I had 2 ct scans of my stomach for some pains I was having. Could any of these things cause this? Does this sound like peyronies? Do you have any idea what may be the cause of my twisted penis and crooked urination?

Sounds like a visit to a urologist would be a good idea. MG

 

June 2008

i am 16 years old and when i have an errected penis it cureves upward more that 30 degrees (i think) and it herts when i try and push my penis down, i can straighten it out but will it effect me when i have sex??, i am embarresed about it, should i be??

No. MG

i'm 28 years old, i had an Nesbit operation in Feb 2008. the erection seems to be good now but im still worry about the pull-back force of this procedure against the erection force, is it the reason cause ED after 10-20 years when i become weak?

No, there is no need to worry about that. MG

I was reading through your forum and did not see any questions regarding a young adolescent. My 12 year old son has told my husband that his erections in the morning bend down. He was concerned enough to mention it, so it must be by more than by just a few degrees. Do we address this now with a doctor or just wait and see? I am his mother and have Dupuytren's contracture in both hands. One operated on when I was 45. Both my parents have it in one hand. I saw in one article that men with Dupuytren's contracture tend to have PD. Could I have given him this?

If the urethra opens in the usual place (on the head of the penis), it would be best to wait and see as he gets older. If it opens on the underside ("hypospadius") you should talk to his pediatrician. He does not have PD but congenital curvature, which unlike PD is not related to your family history of Dupuytrens. MG

It appears from everything I've read, that I have some form of Peyronie's Disease. This came about rather suddenly—over a period of just a few weeks. My penis bends to the left and almost appears as though it is "broken," about an 1 1/2 from the tip. Strangely though, I haven't seen it mentioned that anyone's penis (those suffering from Peyronie's) easily bends at the point at which it appears "broken." I can easily bend it to the left at the point where it appears broken, but not to the right (as with any erection). It makes it difficult to insert at sex because it bends so easily at that point.

Even a slight reduction in diameter at one point can cause a tendency for the penis to buckle or "hinge" at that spot. MG

After being diagnosed with peyronies nearly three years ago the results for me were not completely catostophic as I thought they might be at the beginning. I took 1200 units of vitamin E per day for the first 18 months. I now still take 400 units of vitamin E per day. I have no pain when errect but I have lost 2 inches in length and 1 inch in girth. The situation seems to have leved off and I do not think it is getting any worse. I have never read any other comments regarding whats down road for peyronies patients so I thought my factual data might help new comers to this disease. I am not looking for any opportunity to regain length or girth because I would truley worry that what I have left would be gone.

Thanks for putting this out to the forum readers. MG

I'm 17. My penis is curved at the base slighty to the left and around 45 degrees upwards. I'm still a virgin. It's been that way for as long as I can remember. Do I need to see a urologist?

Might not be a bad idea, if this is bothering you. MG

I just realized that I must have PD. I am 55 and am experiencing pain with a full erection and also minor curvature. Also, some shrinkage and very little sexual drive which I relate to the pain. All this started about 2 months ago, what do you recommend for treatment. I just started taking a vitamin E supplement, 400mg/day. Is that enough and will a creme help as well? Anything else I can do at this point to stop the pain?

Vitamin E (400 I.U.per day orally) is an accepted treatment option for early PD. Fortunately the pain will resolve on its own, but this will take months. You may want to take ibuprofen prior to sexual activity. MG

I'm 20. My penis is bend downward, has a thick band of hard tissue on the underside and i have a normal fingers. But when my penis erect, it doesn't hurt. But after the ejaculation, everytime it's erect, it's start to get hurt. Is it a PD?

This is not PD, but congenital curvature. If it is severe enough to be a problem, surgery is the only remedy. MG

I have had PD for more than a year now. When I get an erection my penis feels huge but when I touch it or masturbate it's smaller than the 7 inches that it use to be. Do other men have the same sensation of a big penis when they have an erection or is it my imagination?

I'll put this out to our readers. MG

My dick bends downwards when erect. But it has been this way since I have known. I do not have any pain when erect.Have good ejaculation. But I am just concerned about the downward curvature. Is there any treatment to make it straight or can I leave it the way it is. I am also planning marriage at this point. I am 28.

You can leave it the way it is. If problems develop with your congenital curvature, you can decide whether you want to have a repair at some point in the future. MG

 

May 2008

I used to think my curvature was due to peyrione's but now I am leaning towards it being congenital after having read some of the messaged on your forum. My penis bends very straight upwards (towards the sky) upon erection. I can bend it a little bit downwards only, and it won't bend completely straight. When it is flacid, the penis has no curvature at all. I am 23 years old, and I have had this condition ever since I can remember. Is this congenital, and if so, do I have any treatment options besides surgery?

In a word, yes it is congenital and no, there are no effective nonsurgical remedies. MG

I'm a 54 year old male and otherwise in good health. About 6 months ago I suddenly developed a right curvature to my penis. The curvature is sort of dramatic compared to my penis' normal state. In combination with this on the right side of my penis near to my pubic area the circumference of my erect penis seems to be "defalated" or smaller than say and inch of so beyond that area nearer to the head of my penis. Through self examination I noticed a lump about the size of small pea on the right side in the corpora cavernous of my penis. Since I'm not a doctor and don't pretend to fully understand this part of my anatomy, I'm a little confused about where this fibrous thickening takes place exactly. There seems to be a long tube running along the right side of the penis and this thick area the size of a pea is located in this tube, whatever it is. From looking at the diagram on your site and others I can't determine what this tube is, and whether or not the thick area I'm feeling in this tube is perhaps caused by fibrous thickening or something else like a cancerous tumor. I don't have any pain during erection but because of the sever curvature of the penis it is uncomfortable to have sex. I'm also embarrassed by this sudden curvature that I have developed. In your opinion is this Peyronie's Disease or could it be something else?

Sounds like PD to me - I'd suggest seeing a urologist. MG

I'm 21 years old and think I have PD. It started when I injured myself. For three weeks I had painfull erections. Then all of the sudden it started to bend. Over the last few weeks the bend does not appear to be any worse(has not gotten any better though). Also the pain is still there although it has dulled down considerably. Also I can stil get erections quite easilly. I am trying to see a urologist as soon as possible, but I don't have insurance. What should I do? I am very worried about long term effects as well. Also I assumed it would be a good idea to abstain form sexual activity.

Start taking vitamin E 400 units per day, resume sex when pain is resolving. MG

I am 19 and I have had about a 20 degree curvature downwards as long as I've had erections. It is extremely rigid when erect and painful if attempting to do anything requiring flexibility. First, is this PD? Second is it likely that it can still go away if it's been this long? Third, what is a good, non-surgical, treatment?

This is not PD and it will not go away on its own. At this time there are no non-surgical remedies for congenital curvature. MG

My husband is 58 and has recently been diagnosed with PD - my question to his urologist was does increased sexual activity help the vitamin e work more easily - the answer was no to us - so how can I help my husband deal with this - it obviously has affected his ego and willingness to be intimate? I understand the pain involved is quite intense, but I do not understand how we are to know if the vitamin e is working. We were told about 6 months of use and we might see signs of change - does the vitamin e cure the PD or will he always have to take it to reduce the build up? This has been a very unique situation for us since we are 12 years different in age and our intimate relationship has always been a very active one so the change in our sexual relationship has, not put a strain - but a different twist on things. Any suggestions other than the vitamin e? Would reduced use of tobacco help this situation. He rarely drinks alcohol so I do not need to ask about the reduction of its use. Any further incite would be helpful - he is not the type of person to ask for help and I am since this has impacted our life on the most personal level.

Maintaining a good level of sexual activity, reassurance, and open communication are essential. Avoidance and loss of intimacy are always a risk in PD. MG

Could you ask your readers if any of them have had the "graft surgery" personally and could you or they explain their experience. What degree of success; how long to recuperate; what, if any loss of sensation or impotence as a result of the surgery. Is the potential for impotence high? Does impotence mean the inability to get an erection? If so, does any of the usual aids; rings, Viagra, etc., help with impotence after graft surgery? I believe there is graft tissue taken from the inside of the thigh. Can you confirm & describe that procedure and what type & size of scaring are you left with on both the leg and the penis? Also, one of your readers indicated that they were helped with acupuncture. Is there any way to get more information on this process - which herbs - how do you find this acupuncturist or one in my area that would be knowledgeable to perform the same procedure?

I'll put this out to the forum readers. MG

What degree of curvature should necessitate an operation? My penis was about 7 inches erect and the condition has shortened it to 6, if I measure it underneath from base to tip, but 5 if I measure it on the top side because of the curvature. How much does Nesbitt's procedure shorten the penis? I have read that it can shorten it by 1mm for every degree of curvature. In my case this would mean that it would 45mm, i.e. nearly 2 inches! Would the rigidity I experienced prior to suffering from the condition return to the penis post op?

The mean shortening in one study was about 2 cm. Correction of a 45 degreee bend would not be expected to reduce length by 2". Your original rigidity may not completely return. MG

a few months ago my boyfriend and i were having sex and his penis made a popping sound. the popping sound seems to have been the result of us moving in opposite directions, causing it to bend. his penis used to be straight but now it seems to be gradually curving to one side (the shape of a "J"). the curve is noticeable during erection. he felt pain at the moment when it popped, but he has not been feeling pain since then, although the curvature is noticeable. there is no swelling or bruising of any sort. should visit a doctor about this? are these signs of PD? is it possible for this to develop into PD?

This kind of injury during sex can lead to PD. It might be a good idea for him to see a urologist. MG

I am 43 years old and had surgery (Nesbit procedure) 16 years ago. The surgery was unsuccessful and I still have a 30-45 degree downward bend. I continue to have good erections and sensitivity, although somewhat diminished after the surgery. Would you recommend a second surgery? Have there been any new procedures or improved techniques in the past 16 years which may increase the chance of success?

Your situation is not terribly uncommon - sometimes severe (>60 degree) congenital bends are incompletely corrected. If the current deformity presents problems, a surgical revision would make sense. Techniques are still very similar - make sure your surgeon is experienced in this field. MG

I used to have a dime sized bump on my penis.It came after my wife go to rough during sex.It was painful .It caused an 45 degree upward curve.After 4 to 6 months it was mostly straightened out with most of the curvature gone.I was straight, close to normal for me.The bump was gone .It is eight years later.I never participate in rough sex anymore but in the last 2 years my penis has curve upwards again . It is about 90 degrees up.I do not feel any bumps .This problem makes sex difficult.I am 44 years old is there any hope for repair.

The long time span and severe bend decrease the chance medications will work. Surgery may be a consideration. MG

I have recently been diagnosed with peyronies and have been put on a regiment of verapamil cream, Potaba and vitamin E. I have also spent a lot of time on the internet researching it. I have come across a herbal drug called Neprinol which claims it can help along with vitamin K2 have you heard of this and is there any truth to it?

There are no good, peer-reviewed clinical trials confirming its effects. MG

For the last 2 years I have been struggling with the fear of Peyronie’s disease. I first discovered the disease in my Pathphysiology class when I saw a picture about it. In terms of symptoms there was a period in 2005 for about 1 month that I would have sudden pain in my urethra (not when it is erect). I assumed was something I ate, or drank (I was taking some diet drugs at the time that includes Ephedrine, caffeine, and aspirin) I have never noticed a sudden change in my penis curve/shape. A part of me thinks there has been a change in the curve since I hit puberty till now (I’m 22, and I started about 12-13). There has never been any pain, or swelling in my penis shaft in my life (in terms of the outside). I don’t have any hard plaques but I noticed small bumps on the bottom half of my penis/under it. It curves to the left some. During a non-erect state it hangs on my left side of the testis, about the middle/bottom of it. I’m proposing to my girlfriend to marry me in August, and we plan to be married on June 6, 2009. We both are virgins….and it has been a deep fear of mine that if I have Peyronie’s Disease that our wedding night would be ruined or that it would be too painful for her/me to have sex (Yes, I understand the first time has some pain due to tearing of hymen). I want it to be a pleasurable, and amazing night that was worth waiting for. I have researched some on the internet from to time. My plan was/is to go at the end of the summer to a Family Dr, and possible see what he thinks. I am paying for my own health insurance, and trying to save all I can for her ring. From the sounds of it, does it seem like PD?

I don't think you have PD. Save your money for the ring and I bet things will work out. MG

 

April 2008

i'm 45 yrs old today and about 18 months ago i noticed and hour glass shaped penis i didn't know what to do so i wwent to my fathers urologist he said i had peyronies and it would take time to heal and for the last 13 months i have been taking 4 packets a day for 1 yr of aminobenzoate potassium,2 grams i have gotten all shape back about 85-90% what i'm worried about is he is about 3/4 of a inch shorter and im worried my penis wont get its full length back i will take this medicine to 2 yrs but do you know if i will get my full length back this whole peyronies thing has hurt me sexually mentally and physically.

Unfortunately, lost length is usually not recovered, even with surgery. MG

I've had PD for about a year, having had pain for the first six months with no other symptoms. I visited a urologist last October who suggested 800 IU's of Vitamin E daily...this had little effect, the PD worsening steadily. I still have pain during and after erections, but approximately six weeks ago a noticeable indentation began on the left side and has progressed across the top center of the shaft causing the first signs of curvature up and to the left. A second urologist prescribed Potaba, but with the expense and warning of G.I. distress, I am looking for other options. My question...is Neprinol as effective as touted?

Neprinol is an option but there is no peer-reviewed, placebo controlled data showing it to be effective. MG

I am 21 years old. My penis started curbing downward when I was about 16-17 years old. About 6 months ago I noticed a small lump under my skin above the left corpora cavernosa visible only during erection wich disappeared after a week or two. Recently the lump reappeared in the exact spot. It is located about 4cm under the head, it has the size of a rice bean and it's movable in any direction to about 5mm. I don't feel any pain during erection or intercourse. Could I be having Peyronie's disease?

Don't think so. This sounds like Mondor's syndrome, which is a temporary, self limiting blood clot in the superficial penile veins. MG

I am a53 years old man and I started on a drug called atenolol 25 mg 2 years ago, and within 4 months I started noticing a curvature and shortening of my penis. I asked my family Dr. and he told me I was just getting old and that the drug had nothing to do with it. I started doing research on the net and noticed that when I typed in side effects for this drug, PD keeps coming up. It never talks about it, just mentioned it. I now notice that there is a hard almost shaft like that runes the entire length of the penis. Is there anything I can do about this?

Although firm proof is lacking, there seems to be a statistical correlation between the use of beta-blockers (like atenolol) and PD. I would suggest switching to an alternate drug if this is possible, and seeing a urologist. MG

I am 22 years old and wonders , because since i was little i have always had a curve to the left in erect condition. It starts to bend to the left from the middle of the penis and bends about 1.5 cm . It also is a little rotated against the left and a little fatter on the right side. Havent had sex so I don’t know if this will be any problem for me. And iam scared of showing it to a girl in future. And I also wonder how long is a ordinary erect penis in length for a man in my age?

About 14 - 15 cm. Slight curvature or irregularity is normal. MG

I’m interested in the course of acupuncture. I have what appears to be a 1 inch band around the lower end of my penis. There is an almost disconnect between the lowest area and middle are after the banding. I have some pain but no ED. Is it possible to exchange information on this site? Is it possible that masturbation might be the cause of Peyronie’s?

Only if it is unusually traumatic. MG

I am 52. About 7 months ago I had a bent erection with indented penis. The bend has gotten better, but I still have some indent and some pain during intercourse. What do you you suggest? Will this cure itself or should I go to a urologist?

The pain will go away by itself; the indent may not. MG

I am 21 years old, and I have had rather severe curvature of my penis for as long as I can remember. I have never experienced any pain from erections, nor can I see any scarring or lump. I did see the comment saying that if you are born with curvature, you dont; have PD, however my penis shape matches several sketches I have seen of people with PD - the "before" picture on the page detailing the Nesbit procedure being a case in point.

Having curvature does not equal PD - you don't have it. MG

Just a note to let you know that I suffered PD 2 years ago. Plaque deposited over a week or so and badly distorted my erections. Sought prompt treatment with high intensity ultrasound (used for tennis elbow) Had 6 treatments with significant improvement. Followed up 6 months later with 2 treatments. Now have only slight bend towards end of penis. Intercourse comfortable. Much relieved. This type of treatment has around 50% success - based on small number of patients. Can highly recommend this non invasive no drug treatment.

Ultrasound has been used for many years and helps considerably in some cases. MG

 

March 2008

I have had PD for about 5 months now, at First I had no Curvature but over the last month It has started to bend and coause pain on erection, is it too late to try some medication?

No. MG

My 45 yr old husband was diagnosed with Peyronies last year and was told to take Vit E capules, although was advised it probably wouldn't make a difference. He is due to see a specialist in a few weeks, but is becoming increasingly distressed with the prospect of having an operation and the risk of impotency. He is starting to obsess over his worth as a man should the operation be unsuccessful. Nothing I say allays his fears and he won't seek help elsewhere. I am concerned for his emotional wellbeing and was wondering if there is a support group in Brisbane who I could contact for advice.

I'll put this out to the readers in Australia. MG

I am 64 years old and my Doctor suspects that I may have Peyronies Disease. I have lost length and girth over the past 18 months and there is a slight downward bend in the erect penis. I do not have any pain when erect, I have no problem ejaculating and I can not seem to feel any plaque around the Penis itself. Do you think that I have PD

This sounds like PD. Based on the time interval, I doubt it will progress. MG

I just turned 29, and I'm still a virgin, so my experience in these matters is essentially zero. I intend to stay a virgin until I'm married, but now marriage seems to be much closer than I expected, probably within the next 2 years. I have had a bent penis as long as I can remember, or I should say as long as I can remember having erections anyway. By my measurements, I would say the bend is between 60 and 70 degrees. It has gradually progressed to this point over the years, but has been pretty stable for at least the past 3 years. My questions are as follows: 1.) Is this angle severe enough to limit sexual intercourse? I imagine it would be...at least enough to have to worry about the mechanics of the intercourse and to not be able to just enjoy it naturally 2.) If so, is it severe enough to need surgery to correct? I don't think I would need a perfect 0 degree penis, but something less than 30 degrees should be ok, right? 3.) If surgery isn't necessary, what treatments would you suggest?

1. If the bend is downward, I'd say yes. 2. If it make sex difficult, surgery is reasonable. 3. There are no non-surgical remedies for congenital curavature. MG

when i was 14 i start doing masterbation and since then at age of 28 i am doing it continuously. because of yhis my penis is curving on left side from base. it looks smaller, there is no hard erection, and veins on penis looks like worms

Does not sound like PD. MG

Your responses are medically worthless. You could be a live at home mother for all we know. ....Why don't you give it up? You lack anything to add...Unless you are a really good MD, who could use his brain and think outside the box, shut this POS web site down....you offer nothing here. Your MD skills do not show much. If you want to contact me (unlikely), please do.

This patient was extremely frustrated by his PD. I contacted him and here are his subsequent replies:

My words of anger only stem from this frustrating disease, I know not much can be done. I guess I am tired of hearing the repeated "you're stuck with it" diagnosis... "stuck with it", Springfield, Virginia

Thank you for your personal responses. Very kind, especially given my rude e-mail to you. I have had this 4 years now, pain is gone, upward and left lateral curvature remain. (I would guess >30 degrees in both measurements) Plaque on the top just behind the head, and bilaterally further down. Cialis helps, but the plaque on top makes it difficult to maintain even a modest erection. I have visited the Tidewater Clinic already, and while impressed by the Physician, left with basic info. It's amazing though how much length and girth have been eliminated. Thanks for your time, and I hope you accept my apology for the original harsh message.

The truth is, a lot of PD patients are really "pissed off". MG

I am only 19 years old. I started to notice that my penis was curved to the right (during erection) probably around 6 months ago. After hours of research, I am 99% convinced that I have Peyronie's. I have a significant curve and I can feel (and see) the plaque. It is on the right side and somewhat on the underside causing a curve to the right, and a bend downward. This is very depressing for me because everything I read is that the average age for Peyronie's is between 50 and 60 years old. Is it possible that I really have PD at such a young age?

PD can occur at your age, though it is unusual. The good news is, younger patients seem to respond better to medications. You should see a urologist. MG

Last year I started taking Pravastatin 40mg and Lisinopril 10mg for cholesterol and BP respectively (neither extremely high). A couple of months later I developed a Peyronies condition with downward bending and an hourglass-like indentation. Cause and effect? I am 61 years old and have never had this problem. I noted on the Mayo Clinic's Peyronies website a brief mention about a possible link to statins.

At this point research would indicate emphasis on the word"possible". There is no data proving statins cause PD. Based on your own experience, it might be reasonable to see if your doctor would be able to use an alternative. MG

My verapamil 5% gel did not come with driections for usage. Do I apply onto penis itself or insert into penis using syringe?

Apply it topically onto the skin of the penis. MG

I would be very interested in hearing from patients who actually had that type of surgery removing the plaque and replacing it with various grafts. Such as the success rate; problems encountered; length of time to recover, and anything else one should know about this type of surgery.

I will publish responses. MG

18 years old. I have a curvature in my penis since I can remember myself. I was born with this . The amount of curvature is about as much as this picture of wikipedia shows about Peyronie's disease. Since small I was ashamed of it very much and it has added to my character over the years and made me more "shy". I do not experience any pain or other problems, it's just the shape. It goes left about the same amount as the aforementioned image. What can I do to fix this ? I have had sex and my gf didnt say anything about it but still it is a problem for me. I went to a urilogist but here in Greece they probably dont know about this . When I went to the doctor he told me to have circumcision because my skin was a bit more than needed (phimosis) and they also did something to the "thread" of it (i dunno how its called, the one you also have under your tongue) So they fixed the length of the thread and did circumcision and I dont have any pain or anything but the curvature makes me feel ashamed of myself .

The Nesbit procedure is an operation that will correct the congenital bend. MG

I’m 62 and have been diagnosed with Peyrones. I now realize that symptoms began over 1 year ago. I consider the condition to be severe. ( My penis is skinny, bowed and touches my left thigh during an erection. My urologist suggested an experimental procedure consisting of 12 shots of Interferon over a 12 weeks period. Either that or surgery. I saw two Canadian clinics on the internet who were touting treatment with Ultra-sound to break up the plaque. Any thoughts on the two treatments?

There is placebo-controlled clinical trial data confirming benefit from interferon, but such proof of the effect of shock waves and ultrasound is lacking. MG

I am 30 years old and recently I found that I have Pyronies disease. I went to a Urologist and he told me to take Vitamin E. I have had curvature in my penis for as long as I can remember. It bent to left and about 45 degrees. I am married and I can do intercourse. I did semen analysis and everything looks normal. But this curve make me bad while doing intercourse and I feel like I cant able to do the way I want to. Sometimes I get pain at the tip of the penis when masturbating or having oral sex. My question is is this in a severe stage or whether taking vitamin E can solve this problem.

If this problem dates back as far as you can remember, vitamin E is unlikely to help. MG

Having the peyronie's symptoms starting in 2006 after several urological procedures, including TURPs, with the catheterization accompanying each procedure, I tried potaba for a few months with no success. However I have received great improvement and reduction in the curvature after applying topical verapamil 2x a day and also taking neprinal with co-enzyme 10 during the past two months, after reading that suggestion on your forum.

Thanks for the follow up. MG

would there be any benefit to regularly massaging the area that is damaged while in the flaccid state to try to stimulate blood flow to the area? I know that massage to normal muscle tissue will stimulate blood flow to the area, but at the same time, since I'm not an expert, I don't want to cause even more damage to tissue that is already damaged.

I don't know that this would correct curvature but it wouldn't hurt. MG

I’m currently 23 years old and have always had a slight downward curvature (20 degrees?) to my penis. This has never been a problem, never bothered me, and seemed to be an advantage for my partner and myself. About 2 years ago I had a circumcision performed, and a portion of my stitches didn’t heal correctly, leaving me with a rough scar but still nothing I worried about. 9 months ago I started noticing my penis was curving to the right and downward more in the direction of the scarring. I know this is sometimes an unfortunate affect of circumcision, but it doesn’t appear to be from tightly stretched foreskin. I don’t believe I have PD from everything I’ve read, but I believe my penis is continuing to get worse and now has a very noticeable bend. This has begun to interfere with sexual intercourse but not to the point I can’t function. I have noticed more and more that during intercourse my curvature causes my penis to slip and occasionally bend. Currently I’ve had no lasting pain, but I was curious, if this continues at I at risk of developing PD from my actions?, and does congenital curvature normally continue to worsen?

Congenital curvature can expose the penis to abnormal mechanical forces, which in some cases can lead to scarring and further bending. MG

I think a masturbation technique caused a permanent curvature in my penis. It curves up, but slightly oddly, as the top of the shaft is shorter and straighter than the bottom of the shaft, which has most of the curve. It is not abrupt, but sloping. The only effects seem to by psychological and I think I have experienced a minor "attack" of phycological ED on two occasions. I am wondering if you think I have PD or just a developed curvature. If I did not have PD, I was wondering what your opinion of the penis braces devices that claim to stretch barely a mm at a time and break up the plaque, causing the penis to straighten.

This is not PD, and I do not think a stretcher would help you. MG

 

February 2008

I am a 24 year old student who was first diagnosed with PD at age 21. I have been seen at the Mayo Clinic in Rochester and was told that a microscopic surgical procedure could correct the issue but I would lose about a centimeter of length. I was told I would have to wait a year to make sure that the issue stabilized and did not get better on its own. I am hesitant to try surgery as they told me one risk is that they are making an incision to remove scar tissue that in itself could lead to more scar tissue. In addition I exercise regularly and was told I would not be able to lift over 10 lbs. for 6 weeks in addition to no sexual activity. Besides waiting for clinical trials I feel at a frustrated loss. I have tried Vitamin E to no avail. It would be worth losing the muscle and definition from my weight lifting if I know it would be successful. I certainly do not mind losing a centimeter, but I am most concerned about gaining back the loss of girth that I previously had. I have only mild curvature but the tissue that has been affect now pinches along the sides causing a non-uniform look, loss of circumference, and areas of lost flexibility. If you are aware of this microscopic surgical procedure do you know if it would result in regaining the lost circumference?

The microscopic procedure is probably a variation of the nesbit - which may not be effective in restoring lost girth. MG

I've been having what sounds like peryonies, with a 30* bend to the left with pain near the left base of my penis. About 15 years ago, my girlfriend at the time squeezed my erect penis very hard at about the bend point. It was painful at the time, but she said that the had read this cause a longer orgasm. I'm thinking she squeezed way too hard, and the problems I'm having now are related to scar tissue from that incident. Is this possible 15 years later?

Yes it's possible. MG

I am 50 and was diagnosed with PD about 12 months ago. At the time I asked the urologist if it was associated with the erectile dysfunction that I was beginning to have as well. He said no, that would be a psychological problem. Now I read on your website that 40% of PD sufferers also have ED problems. Specifically, my problem is that the rigidity of my penis is only about 80% of what it used to be and it seems to be more difficult to achieve and retain an erection. Could PD be causing this?

PD can indeed cause erectile dysfunction, such as loss of rigidity. MG

In 1995, at the age of 49, I was diagnosed by a urologist with Peyronie's disease. My penis curves about 45 degrees left and slightly up, with scar tissue on the top near the base clearly felt to the touch. At the site of the scar tissue, there is a marked narrowing of the shaft when erect. The doctor gave me the option of that time of 1.) Seeing if it got worse, and 2) surgery with the possibility of never having an erection again, so I did nothing except take Vitamin E 400 mg or units daily. Never had diabetes, or penile injury or catherization. Now at the age of 64, I have trouble with any erections, so my primary care physicians prescribed first Viagra and later Levitra. However, the warnings with each prescription warn that persons with PD should not use it. 1. Is there any way to reverse this problem outside of surgery? 2. Is there a real issue with PD and Viagra or Levitra usage?

1. At this point in time, surgery would probably offer the most. 2. This is a legal issue for drug companies, since they didn't test these drugs in a group of men with PD. The fact is, research suggests Viagra and Levitra may actually help men with PD by inhibiting further scarring. MG

About 5 months ago, my normally straight, erect penis changed to where it bends, at approximately mid-shaft, nearly 45 degrees to the left. Their is a strong indentation on the left side where it bends. It has had a marked effect on rigidity and consequently sexual performance. This change was essentially overnight - not gradual in any way, but just started one day and was significantly bent. I can't relate this change to any trauma. I saw my urologist who said it's probably Peyronie's disease. However, from my reading, it sounds like a significant bend like this should be palpable. He said he did not feel any hardening or calcification - and in my self-exam I did not find any either. He feels that I should just wait a year and see what happens - i.e. if it corrects itself. While I'm not anxious to jump into surgery or anything like that, I don't feel comfortable with the diagnosis without evidence of plaque build up or something more concrete. I'm also uncomfortable with just waiting since the condition could worsen over time and some literature suggests that the first 6-12 months is the time in which to consider non-surgical treatments. Should I see a Peyronie's specialist?

Probably not a bad idea. MG

I guess I masturbated too hard or somthing, I literally felt a tearing feeling under the skin of my penis. It was a small tearing but it felt very weird. Did I tear a piece of my tunica? It has been almost a week and there is still some weirdness there, no pain, but it just feels weird. When I am even slightly erect it feels like there is a small dent there. My question is will it fully heal without plaque or will there be some plaque? Do all tunica tears lead to scars?

A tear of the tunica would have lead to considerable bruising and swelling. Absent that, I'd say you'll be OK. MG

I WOULD LIKE TO KNOW WHAT IS THE APPROPRIATE DOSAGE FOR LONG TERM USE OF VITAMIN E AND FOR HOW LONG MUST ONE USE IT AFTER PEYRRHONIES HAS BEEN DIAGNOSED.

400 units daily for at least 18 months. MG

What experience do you have with Dr. Paulo Edygio's procedure? He is a doctor in Sao Paulo Brazil that is working on this geometric procedure that is a surgical way to take away the curvature and also restore the length. Does it work? Are there doctors in the USA using this procedure?

This involves grafting of a rather extensive nearly circumfrential relaxing incision. I have had a great deal of experience with relaxing incisions, having been the first to publish this method back in 1991. It remains to be seen whether pushing this technique to its limits will offer safety and real restoration of length. MG

I just turned 55 in January and the symptom for peyronie's disease appeared overnight. It is an almost 90 degree development in my erection. I have been placed on blood pressure meds for 5 years, have take testosterone treatments for low libido, have arthritic complications in certain joints and take a variety of meds for pain, sleep, muscle relaxation and cholestorol. This is just another problem that I don't need or want. Being married 30 years helps in the fact that the need for performance can be mitigated by just that fact, but it is unnerving that this apparition and obvious symptom has become another thing to contend with. I have two heart blockages that haven't required stints or angioplasty as yet I am hoping that time will take care of the problem, but at my age time is at a premium. Pain is not an issue but ED has been for a awhile==therefore the testosterone treatment, which has seemed to bring up the old urges. Intercourse is naturally infrequent but the embarrasement of the obvious disfigurement is emotionally distressing. Has Vitamin E been thought to be a succesfull treatment to others. I believe that it the first, less invasive step to remedy the symptoms, along with precious time. This has been an unwelcome surprise but so far not completely unworkable. What are some of time elements that others have seen to be an average recovery?

Usually 12 -18 months will give you a good idea of just how much difficulty to expect. MG

In professional medical sources such as "Urology" and "Journal of Urology" there is a growing awareness that Peyronie's can be viewed as an autoimmune disease. In my experience Peyronie's is caused by inhaling carcinogenic chemical fumes that chemically cross-link proteins in the erectile nasal turbinates.

I will look forward to examining the evidence for such a hypothesis. MG

I am a 44 year old male with PD for 1 year. My impression is that the postion (and associated curvature variation) of nodules is changing. Is is possible to have multisite lesions and if so does that reduce the likely benefits of Nesbitt's procedure as a primary management strategy (unless undertaken in multiple sites)?

Yes multiple sites can be involved. The disease process must be completely stablized before undertaking surgery. MG

I have been through vitamin E therapy and have been using a topical for approximately 2 months. If there has been any change, it has been for the worst. If I am subject to scarring (plague) wouldn’t surgery cause the same scar tissue to develop? I am really nervous about having any surgery done to my penis

When the proper procedure is done at the right time, the scar caused by surgery will not defeat the goal of surgery, which is to straighten the penis and allow you to resume sexual activity. MG

My husband is 43 years old and over the past couple of years we have noticed a lot of differences in his penis. Firstly for him it was just pain, a feeling as though he had been kicked down below. It wasnt really affecting our sex life so when I told him to see someone about it he just said if it got any worse then he would. For a while he didnt say anything about it but I knew that sex was uncomfortable for him and his penis was definately bending slightly, firstly in one direction and now more recently in another direction. Slowly our sex life has diminished from about 3 times a week to once or twice a month. Nothing had been said between us until tonight when it was obvious his heart wasnt in it and he mentioned that he was concerned about his penis. Not only was it still bent but there was pain up the sides and when he had an erection there was very little blood going to the head. I told him I knew all of this as I could no longer feel him inside of me. He admitted that he had no sexual thoughts or drive anymore and I am now expected to do things on my own (if you catch my drift) I am devastated as not only did we see this coming and nothing was done about it but also we have lost any kind of closeness. I asked him to go and see someone but have been told that I have no idea what it is like to face something like this as a man and it isnt as easy as a woman

A good comment on how untreated PD can undermine intimacy in a relationship. MG

I have been diagnosed with dupytrens disease in one of my hands (right), and have plantar fibromatosisis in both of my feet and believe I also have Peyronies disease in my penis. A podiatrist performed surgery on both of my feet in June of 2007 and the end result was considerably worst than when I was first diagnosed. What kind of doctor do I need to seek to be treated for Peyronie’s Disease?

Someone with special interest and experience in this problem. MG

I am 46, and about a month ago first began noticing a lump on the left side of my penis near the head, accompanying a leftward bend. The lump seems to have grown fairly rapidly during the last couple of weeks, and is currently about the size of a kidney bean. I have a small amount of pain with erection. My doctor has diagnosed Peyronie's and has prescribed Colchicine and Vitamin E. From what I am seeing on the web, it does not appear to me that there are any significant studies showing that Colchicine promises any significant hope for improvement over placebos. From what I'm reading, for most, the pain seems to go away with time, while the bend remains. Are there any reputable controlled studies showing any merit to Colchicine? I am not enthused about risking the possible side effects without some reliable indications of effectiveness.

Unfortunately there are no good placebo - controlled randomized clinical trials showing benefit for any oral agent in the treatment of PD. MG

I am particularly prone to keloid scars. Corticosteroid injection helps them immediately. Is there a link between my keloid scars and Peyronies, and might corticosteroid injections help my PD as well?

Despite some similarities, PD and keloids are different animals. Corticosteroids don't offer much to the patient with PD. MG

I'm 20 years old. I think I got PD after injuring my penis when I was much younger - perhaps around 12 years old. It was a cut on the left side from a fall onto the top of a brick wall. I didn't notice anything wrong all the way back then because I was young and it was most likely before I started getting erections. But since puberty (and subsequent erections), I've been bent to the left by about 30 degrees. I've never had any pains in my penis, but the curvature does bother me. Would you recommend surgical treatment?

30 degrees is not that far off the normal range, but if this really does bother you, a Nesbit procedure would help. MG

January 2008

I am 21 years old, and have been having trouble with sex because of painful erections, and also lack of sensation in my penis. I do have slight curvature but nothing that prevents intercourse. However because of the pain and loss of sensation it has become difficult to have optimum sex with my partner. I have seen a urologist and at first he gave me levitra and that worked to help maintain erection, however the pain and loss of sensation was still presistent. I still lost an erection once, but regained it even on the levitra. Going back he suggested that I start using Transdermal Verapamil Gel 15 %, but it is extremely expensive and is not proven to have positive effects. I have also been a heavy smoker for about 6 years and supposedly am allergic to tobacco. Would that have anything to do with my troubles.

First of all, you don't have PD so there is not reason to spend a lot of $$ on verapamil. I am not sure what is going on with the sensory deficit, but I would definitely reccommend you stop smoking. MG

Hello, I have just looked over your site which is excellent. In July 2005 I had a Prostrate operation which seemed to be the start of ALL my problems. Within 5 months my penis bent downwards and I was advised to have a NESBIT which I had in February 2006. It turned out to be the most painful thing which has ever happened to me, it turned septic and had to be dressed 3 times daily for about 3 months, since then, it has now started to bend upwards and I still do not have feeling in it. I was told that I would loose about half inch and I would regain about 95/98% of feeling. It is now nearly 2 years on and I still do not have much feeling, also intercourse with my wife is extremely difficult. What advise can you please give me. Many thanks for a great site. (England)

That is alarming - and unusual for a Nesbit procedure. Perhaps the use of either viagra, levitra, or cialis would help with intercourse - they also may help to diminish scarr, which may be partly responsible for the sensory problem. MG

My ex-husband was diagnosed a few months ago as having Peyronie’s. I have been doing some research on the internet and came across Neprinol as being a possible new treatment for this disease. What have you heard about this drug, and its effectiveness for Peyronie’s?

Neprinol may inhibit inflammation, but there is no controlled data on its effects on PD. Vitamin E is probably equivalent. MG

Since I can remember, my penis has bent downward when erect. I just turned 40, can have sex with some pain at certain times but have never sought treatment or consultation before for it. I will include a picture of my penis erect, will you look at it and let me know if there is anything I can do besides surgery to straighten it? I don't think it is Peyronies, there is no scar tissue that I can find and I cannot remember injuring myself.

You don't have PD, but congenital curvature. Usually surgery is the only solution. Use of a traction device might help. MG

First I would like to thank you for taking the time and effort to provide free information on your website for people with Peyronies disease. I do, however, have a question. For the past few months, I have been feeling a soar kind of pain in my penis, just under the head. The pain is only there when I have an erection. The stiffer the erection, the worse the pain. After reading your website i have checked to see if I can feel hard lumps around the area and I cannot. Also, I am (thankfully) not experiencing and significant bends in the shape of my penis. I have always had a slight curve, but I have not noticed any increase in the angle. I am unsure if this is Peyronies disease or not. Also, I am a virgin so i know it is not an STD of some kind. I am 20 years old. Please let me know what you think... is this peyronies?..

Sounds like localized inflammation of the terminal end of the corpus cavernosum, which will probably go away on its own. MG

I am an 18 year old who is generally very healthy. I cannot remember when I started noticing a curvature of my penis when erect, but it has been at least 2 years or more. While I have not been sexually active, I am concerned that the curvature is severe to affect intercourse - it is bending sideways

I looked at your pictures. This is minimal congenital assymetry - fuggedaboutit.MG

I am 53 years old and my wife noticed around 6 months ago. I saw a doc around 3 months ago and discovered the problem as peyronies. The urologist said take vitamin E and we will revisit it in 6 months. I have taken vitamin e now for 3 months and have not noticed any difference. My concern if I wait the year, will more permanent damage be done? I am nervous about the idea of just playing the waiting game. My penis takes a 60 degree turn to the left. My erection used stand up and now it just hangs down. If it does get back to normal will the penis stand up again? The doctor says to have normal intercourse but that is hard to do physically and emotional. My penis seems to be getting smaller (and I did not have to start with) and it also aches even without having intercourse. The doctor checked for a hernia, but that was negative. I feel like during the day I should wear a jock. Just walking around in dress clothes the movement around does not feel comfortable. Am I just imagining these things or are they somewhat normal symptoms?

No these are not imaginary, but usual symptoms of PD. The pain will go away, but often some degree of length loss and bend will persist. Just how much remains will determine if you need surgery. MG

I am 45 years and had PD for 12 years. I have a god erektion, but my penis is ben very small. from ca. 15 cm (before PD) to 11 cm. I have read about the Jess Extender. Can i troust this produkt, can it heelp me to get at longer penis??? or is it fake?...Thank you for the answer...Sorry for my english. i from Denmark

A traction device (extender) may help, but after 12 years this seems unlikely. MG

I have recently started having what can only be described as a pressure pain on occasions at the commencement of an erection and have developed an upward curvature of the penis. No sideways curvature present.. Also approx midway along the penis shaft is a minor symmetrical lump where ther is a more angular bend. My GP has suggested PD and suggested an ultra-sound, but this did not reveal any plaque, calcification or scar tissue. Will an ultra-sound detect the onset or presence of PD or is there a better detection process. From what I have read, cure is more likely at the early stages of PD. What treatment is suggested at this stage.

Ultrasound cannot always detect plaque. At this point one of the medical regimens would be recommended - verapamil, colchicine, intereferon or vitamin E. MG

I am 67 years old. About nine months ago I noticed my "rare" erection started to bend north. My erect penis is now curved upward a banana. I do not have any lumps, plaque or dents as described by others on this site. It seems there is a cartilage about a 1/4 inch wide running the length of my penis on the top. Is it possible that a penis will atrophy with a lack of regular erections? Can this cartilage loose its flexibility, forcing the penis to curve away from it when erect? If any of this is a fact, is there anything to be done about it?

Sexual function will suffer from disuse. This sounds like PD to me. MG

I am considering nesbit surgery and I was wondering what the results might be if I got it done. What are the chances of the curvature coming back later? What about sensitivity? Will I be less sensitive after? Right now I am able to acheive full erection with no problem, but what about after? Will it be harder to acheive, or maintain full erection after surgery?

Usually a Nesbit is quite reliable. If you are young and healthy, the chance of erection or sensation problems is<5% - have it done by someone with experience in this area. MG

I am a 24 year guy from India and haven't had any serious medical condition ever and got a fit healthy body, but I have been suffering from PD for years... in fact i do not remember seeing a full straight penis of mine! Or, it just might be that I have taken it into notice for last 3-4 years, it might be okay before that, but i do not remember. Recently i contacted someone who advised me Vitamin E capsules. They showed some results within few month. Size was remarkably improved comparing to previous condition but still it is not in proper shape. And for many months its the same shape now. I have discontinued and restarted Vit E dosage, but still the same. WHAT DO YOU ADVICE? Although I have never had pain or erection probs, but i get frustrated seeing it as the size and thickness is good and if just the shape becomes okay, it would be icing on the cake.

If the bend is <20degrees, I would recommend simply continuing with the vitE. MG

Thank you for this helpful forum. I am 35 and I think I have only a mild case of PD. I have had a clear calcification that is like a small visible bump underneath the skin for over a year. A CAT scan (which I had due to urinary difficulties) confirmed the presence of calcifications. My penis leans increasingly to the left even when mildly erect but I have no curvature or pain. Now here's the weird part: When I run my fingers from the base along the very center tube of the penis (either between the corpora cavernosa or along the urethra--it's hard to tell) it feels like there are several little clots or bumps along the way leading to a relatively large (pea-sized) hard lump--not the one mentioned above--right in the middle (mid-way between the base and the head). I think the lump may have gotten worse after catheterization (due to urinary retention). Recently, I squeezed the lump and, shortly afterward, the urine came out in a completely split stream. This doesn't seem to fit with what I've been reading about the scar tissue associated with PD and the fact that PD does not affect urination. So, now I'm wondering if this is different or even unrelated problem. Perhaps I have some type of urinary stricture or, heaven forbid, urethral cancer.

This does not sound like cancer, but I think you should be examined by a urologist. MG

I am 28 and have had a 90 degree downward curvature for as long as I can remember. I know that a Nesbit procedure can fix the problem but with such a severe bend I can loose significant length which I cant live with. Would Tissue Graft be an option for severe congenital curvature to prevent length lose? Would stretching the shorter underside work and will it lengthen enough to straighten it out? And if stretching is an option what are the safest technics that work?

In general, graft operations do not work well for congenital curvature - they are likely to produce erection problems. You cound try a stretcher, such as the andro penis device. MG

I am a 60yr old New Zealander who was diagnosed with Peyronies nearly 12months ago. I also have Dupuytrens Contracture in both hands. As I have a 90degree bend in my penis and am suffering a lot of discomfort with it retracting into my body, I feel that in the long term, surgery will be my best option. I wondered if you would know of any urologists in either NZ or Australia who have some expertise in this field? Also, how much longer would you advise me to wait before taking this step? I have tried vitamin E and Neprinol but don't hold out much hope that these are going to improve things for me.

Based on the degree of bending and the presence of Dupuytren's contractures, I would agree surgery makes good sense. Check for a referral by contacting Dr.Bronwyn Stuckey in Nedlands, Australia. MG

I have what appears to be a growing indentation at the left base of my penis. It looks like scoop has been taken out. It measures about 3/4 of an inch loon an 1./3 of an inch deep. I am 67 years old and have had genital herpes for many years. The area just below the indentation appears quite red. The indentation is only apparent during erection. I also not a slight burning sensation in the immediate area. This is not consistent and does not necessarily accompany an erection.

This could be PD. In Florida I would suggest Dr. Gregory Broderick in Jacksonville. MG

I am scheduled to have surgery to correct PD on 4th Feb 2008. I was not happy with the Nesbit Procedure and was given a second pinion from another colleague of my urologist who agreed that it would do nothing for my hourglass problem. He agreed that the Lu procedure would be of help but did not think that use of harvested tissue (vein I think) was the best approach and proposes to use a manmade material. I think the procedure is to put cuts into the scar tissue, not to remove it all but sufficient to allow the penis to stretch evenly under erection conditions and correct the bend and hourglass. I think he will then wrap the stretchable material around the penis to contain the excised area. I have read that dacron is used for this type of procedure. Are there any proven materials and is it as successful as venal transplant?

I am sorry this response is too late for you - perhaps you can update us with results. In my experience, a patient's own tissue (vein or fascia or dermis) is the superior graft material. MG

I am 62 and one morning a year and a half ago I woke up with "the curve". My GP suggested the wait and see plus Vit E remedy which after 6 months resulted in no improvement. The next step was a Urologist's suggestion of Potoba which I took for 3 months and again no improvement. Now I have agreed to Verapamil injections which apparently cause some bruising. So, my question is if bruising is the result of internal bleeding are we not risking further damage as PD's origins are the result of traumatized blood vessels ? I would also be interested in hearing from anyone who has any personal information on this procedure

Bruising is an expected part of the injections, and will not contribute to progression of PD. MG

I am 65. In November 07', I was having intercourse with my wife 'missionary position' when my penis struck her pelvis bone. There was immediate pain from the collision but didn't think anything about it until a couple of weeks later I noticed two very small hard cysts on the upper shaft of the penis while flaccid. I consulted with a urologist the following January and he immediately diagnosed the medical problem as PD and advised to take vitamin E which I have taken for a year. No improvement from taking vitamin E. The penis while flaccid shows not indication of PD but when erect, a definite curvature of the penis begins halfway down the shaft and extends upward at about a 35 to 40 degree angle. The penis is shorter by an 1&1/2 inches but at this time intercourse is still possible. During the course of the year since the injury occurred, I experienced pain while having intercourse. I no longer have pain, but the PD curvature may continue to worsen with time to a point intercourse may not be possible. Is there any advice to help my PD considering a year has lapsed since the injury?

As a year has passed, it is unlikely that this will progress further. Unfortunately, the best results with all of the medical remedies discussed in this forum are only about 65%. Clinical trials may give us some new treatment options. MG

I am soon to be having a nesbit procedure and plication procedure to fix my downward congenital curvature, my urologist said that i would lose some length of my penis but not very much. He wasn't able to tell exactly how much length would be lost. Is there a way that i can figure out how much length i will lose? how does one measure the degree of their curvature? what is the best way?

Print a digital photo full sized, then cut out enough of the convex side of the bend to straighten the picture of the penis. This will give you a good idea. Average length loss for a 45 degree bend is about 2 cm. MG

I had doulble by pass surgery in 2003 Aug. In 2005 Idevelope what I now know is peyronnies disease Is there a connection between the two in other words did the surgery or the meds have anything to do with my PD. I had a urologist examine me and recomended a possible pump because I did not see a Dr till over a year after I knew something was wrong

No known connection to bypass surgery. MG

 

December 2007

Acupuncture and traditional chinese medicine is the cure. Western doctors will advocate a wait-and-see approach. I had several weeks of pain and inflammation, during which I took large doses of vitamin E and nonsteroidal anti-inflammatories, but otherwise ignored until I noticed the formation of an extreme hourglass deformity at the distal end of the shaft, and severe erectile dysfunction. Being a medical researcher I knew immediately the seriousness of my illness, and saw a local urologist to get a referral to a leader in the field at Mayo clinic. He refused to make any diagnosis or treatment because he regarded the case as infantile in its development, and because no single western treatment has a success rate higher than twice the natural recovery rate. I instead sought a local acupuncturist, well known for his skill at chinese medicine and educated and trained in China. He assured me that proper acupuncture and herbal treatment regularly for three months would soften the tissue with increased blood flow, and that the scar tissue would eventually dissolve. This, he said, was especially possible because I had confronted the disease early, so that no serious fibrosis or calcification had begun. It has been two months now, and my erectile function is back to normal, and my deformity is nearly gone. Please do not assume that there is no cure for something simply because someone tells you so. What they really mean is, they have no cure. Eastern medicine practices operate on principles that are not scientifically understood yet, but for some reason work, and have been working - for thousands of years.

Interesting. MG

About two months ago, I had lots of sex with a girl, about 4 times a night for about a week. After that, the area just below my penis head where the shaft meets the head started hurting. This was on the right left side. I went to a urologist, who saw nothing wrong with it from the outside, and just recommended rest. At the time, when I had an erection for too long, that area would start hurting. I had sitz baths for a while and the pain disappeared in about 3-4 weeks. However, right after this pain resolved, I began developing pain in the entire penis shaft. It was pretty random, on some days the pain would be at base of the shaft, on some it would be at the right side or left side. I wasn't really sure what was wrong with it, and I went to three different urologists, who saw nothing wrong with it again. There was nothing on the shaft of the penis that they felt. However, a few weeks later, I discovered my penis slightly curved towards the right both in flaccid and erect state. When flaccid, the curve wasn't that noticable. When my penis was partially erect, the curve would be a lot more noticable, but when the penis was fully erect, the curve would diminish to about 10-15 degrees. There would be pain that accompanied erection, but the pain actually came after the erection, instead of during. In other words, there was no pain when I had an erection, but there was a lot of pain following the erection, which would last in some form for a few days. The pain actually did not hurt the shaft too much. It was more concentrated as a burning sensation on the tip of my penis, for whatever reason. Is this PD? If it is or isn;t, what is this burning sensation at the tip of my penis?

The poorly localized genital pain, particularly the pain at the tip suggests you had prostatitis. I'm not sure why you had the bend; it does not sound like PD. MG

My penis was perfectly normal prior to 2 procedures for kidney stones, one in each kidney. The use of stints to bypass the tube from the kidney to the bladder were used. After the removal of the last stint, I experienced 3 days of penis bleeding. After the penis stopped bleeding and my kidney pain had subsided, I had my first erection. At this time, the penis had a pronounced upward curve and was very painful. My doctor diagnosed me with Peronies. It has been 7 months since my last stint removal and their has not been any changes. Have there been other reports of similar onset of Peronies after stints, catheters, etc?

Yes, instrumentation of the urethra can lead to PD. MG

I have had PD for about 10 years and am a 42 yrs of age currently…. Not much curvature, but pain during erections… For 4 years I was told to take 400 IU of vitamin E, but the results were fairly negative. Then I saw an Urologist that asked me to take Vitamin E but with Gamma tocopherols which helped significantly. After another year I saw a Homeopathic “doctor” who suggested graphitis which did help. I took the graphitis just about every 6 months for about two years. Then I saw yet another urologist who prescribed colchicine .6 mg twice a day. This did help but at that time I was suffering from shin-splints from running and playing basketball. The drug had an adverse effect on the shin pain and made it such that I could not walk without feeling pain for over a year. I took the colchicines for 3 months and finally stopped because of the increased pain in my legs. My guess is that the drug was breaking down beneficial healing tissue in my legs as a side effect. I also used a vacuum pump about a year ago as suggested by my urologist. I have week valves in my veins and have varicose veins in my legs so the pump had the effect of causing a varicocele. Just writing this to make others aware of the difficulties PD can cause. The Vitamin E with Gamma tocopherols and the graphitis had the best effect without causing some other side effect… I did also try Chinese medicine with little results except for an increased desire for sexual activity… The colchicines probably would have worked well if the dosage was lower and if I did not have some sort of injury my body was trying to heal. I wonder about surgery with a skin graft as the penis continues to feel pain and continues to get smaller… but with my track record I think a conservative approach is warranted.

Thanks for sharing your experience. MG

I have been seeing someone for sometime now and we are considering taking our relationship to a sexual level. I wanted to be honest with him so I let him know that I do have genital herpes. I have not had an outbreak in over 5 years and I can take Valtrex to try to prevent spreading it. He spoke to his doctor who told him not to have a sexual relationship with me of any kind due to the herpes. I believe he stated that because the PD was an autoimmune disorder that possibly contracting herpes would cause a much more severe problems for him than in a male without PD. Is this true? Is there any way to have a sexual relationship together without it possibly worsening his condition?

Peyronies is probably not autoimmunity, but could be aggravated by a severe herpes outbreak. If you are under good control and use valtrex and he uses a condom, I do not see a lot of risk. MG

I am 50 years old, and just came from the urologist, who diagnosed me with Peyronie's disease. I had gone to see him because a couple of days ago I was having intercourse and during ejaculation I experienced intense pain in my urethra at the tip of my penis and even a couple of drops of blood. The curvature of my penis, which has been presen for several months, was almost an afterthought, though on examination the doctor confirmed the presence of plaque. My doctor told me that PD shouldn't be responsible for the urethral discomfort or bleeding, but I'm wondering if the bend in my penis might have caused some irritation, and possibly a crack, in the urethra, or possibly pinched it shut, causing it to crack during ejaculation.

Yes that is quite possible. MG

My husband is 30 and has had PD for about a year ~ so I would have to assume that statistical information is incorrect and that it's just possibly because younger men may not seek attention as often as older men do. I say my husband has had this for about a year because we're not really sure when it began. I tend to believe that symptoms may have started when I noticed it would take longer for him to get an erection. This was followed by a narrowing at the base of the penis, then a change in the head of the penis, followed by an indentation around the penis shaft, nearer to the body than the head, and now a deep "V" type indent on 1 side, deep enough for my index finger to sit comfortably fit in. He says he can feel a bump inside, and after taking vitamin E believes the bump has been moving more towards the head and as another person posted, hopefully up & out. I haven't noticed any improvement and if anything find that the symptoms are worsening. My husband was seen by a Urologist who declined to confirm a diagnosis of PD (although I think it's quite evident). He's lost 1+" in length and of course the circumference has changed with the narrowing and indents. I would not recommend surgery unless it was a case of severe deformity and inability so that's out for us. But I would love more information about the acupuncture recently posted about - as well as the cost of the topical medication some have found improvement with.

I do not have information about acupuncture - perhaps our readers can help. MG

I am 29 and I think I may be developing Peyronie's. My penis, when flacid, has always twisted slightly to the right - at least for as long as I can remember. Recently I noticed that my penis, when flacid and erect, curves to the right (~10 degrees) and the left side of my penis is slightly larger (fatter?) than the left. I have not noticed any plague - although I don't really know what to look for, everything looks and feels pretty normal. I have not experienced any pain with erection and, as far as I can tell, the length of my erection is the same.

This sounds more like congenital curvature than PD. MG

I am 26 years old. Found a small lump on my penis(top right) few days ago. There with no pain during erection.No bend at all.But feel pain when squeez the lump.Worry will be getting worse.What should I do now?

It's probably a skin issue. Avoid squeezing. If it doesn't go away in 6 to 8 weeks, see a doctor. MG

I have yet to be diagnosed and am nervous to go to a urologist. My erect penis curves downward a little when I'm standing at about a 20 degree angle. I'm afraid I won't be able to satisfy my girlfriend. I think it might be normal but would like to have some sort of professional opinion.

To me this configuration sounds to be within the range of normal - I don't see it causing sexual problems. MG

I'm interested in correcting congenital curvature and was wondering what the general cost for a Nesbit procedure(Penis has been bent at a 45 degree angle for over 10 years now).

In California surgery would run around $2,000, anesthesia and facility fee (outpatient) around $3,000. MG

For many years PD did not cause me pain, except at the beginning, the vitamin E I was advised to take, and did not do much for me. I had no problems sexually, while the bending existed, but not perhaps as severe as I have read in some of the articles. Since last few weeks of 2007 I have noticed a lesser erective stage as I would be used too, and of course my wife is wondering why this now happens. Reading through the explanations PD cannot cause impotence, but it can effect the erective state.

Peyronies commonly affects erectile function, although oftentimes in minor ways. If you are experiencing problems with erection, the first thing to do would be to see your doctor for a trial of one of the meds like viagra, cialis, or levitra. MG

 

November 2007

I have had curvature in my penis for as long as I can remember. A small “cork screw” effect. I experience no pain when errect or during intercourse. I have only recently become aware of PD. From what I have read so far, I am a little confussed as to wheather I have PD or not. I am 36 years of age, a little young from what I can tell. Should I get myself checked out or will all be fine as it is?

You only have mild congenital curvature, which will never cause you problems - it's nothing to worry about. MG

I'm 34 relatively healthy and still able to have intercourse. I have had PD for about 1 year. Erections are sometimes painful and prevent intercourse. Rough sex is out altogether for fear of re-injury. I have about a 45 degree bend pulling to the upper left. There is a "deep" indention on the left side of my penis. There is a double-pea sized knot about mid-shaft. I have tried Potoba and vit-E treatments. I am currently taking a vit-E&C pill, vit-B super complex pill, along with a vascodialator pill regimen ( weight lifter buddy turned me on to this). It appears as though the knot may be moving up the shaft slowly. Hopefully up and out. I read about some sort of traction type therapy. Is there a way to do this on your own or is a Dr. required? I am larger than average in length and work in a very physical environment. Is there a way to be in "traction" and still be able to be physically active or do you have to be layed up for this? Is the COLLAGENASE treatment available over the counter or is a prescription required? And finally how do I sign up for any type of this research therapy? I believe my case is severe enough to be of help if a treatment was found that works. The light at the end of the tunnel is an oncoming freight train.

Traction (by using one of the penile extenders available on line) might help. Clinical trials with collagenase may be starting in the middle of 2008 - I will be sure to announce further developments on the web site. MG

Having being diagnosed with PD and found no relief or significant improvement from the use of Potaba I started to look for alternative treatments and came across a doctor in Toronto who is offering Ultra Sonic treatment and claiming some success. Are you aware of this and do you have any comment you feel able to make regarding this approach.

Ultrasound has been used for about 30 years now - without any good evidence of effectiveness. MG

I am a diabetic and have ED. I have been using a battery operated pump for erections. http://www.augustams.com/ Touch II. Sometime in the fast several months, I notice that my erections were curving in the shape of a banana. I also noticed that a bulge was taking place in front of the tension system near the base of my penis. Not sure if the two are related. Has anyone experienced anything similar?

I will post responses. MG

I am 31 and was diagnosed 4 months ago and in that time my PD has grown from a pea size to almost an inch in length all around the penis, just beneath the head. So it's more like a bottle neck but I am concerned that it will continue to spread at this rate. My urologist suggested Vit-E when he diagnosed it, but as seems to be the norm, this hasn't worked. Should I see him again to see how its spread and possibly try other treatment? Is this rate of spread normal?

I think it might be wise to consider additional therapy, like verapamil injections or oral colchicine. At your age it is not unusual for the the disease processs to change more rapidly - and this includes improvement as well. MG

I have been diagnosed with PD and my urologist relates that he feels I have adequate length to make me a viable candidate for the Nesbit procedure. Is there a way to accurately estimate the potential loss in length as a result of this surgery? I know that you’ve stated that the average is 1-2 cm but it in the erect state it appears to be more like a 1-2 inch difference from the longer to the shorter side and the doctor told me that the new length would be that of the shorter side. The grafting procedure is more risky but I thought that adding a graft to the short side would increase length and not decrease it, but many of the sites claim that both procedures reduce length. Why is this so for the grafting technique? Lastly what is your opinion on traction devices and would you recommend its use on a patient with less than severe curvature to the left with conditions being present for @2 years?

You can print a full-size photo of your penis, use scissors to cut out a wedge on the convex side, then swing it down to close the resulting defect and see what it looks like. Also, you can measure your stretched flaccid penis, which will give you a good estimate of post op length. Graft operations don't cause as much shortening as nesbit, but they will not restore lost length. Traction is under study now - no one knows for sure. MG

i am 17 years old and though i have normal erections, i see my penis is a little crooked to the left(aprox 30 degrees)...Is it normal for a man?i am worried because i have not had sex yet and i think i won't be able to satisfy my girlfriend.I am afraid...i don't think it is that Peyronie's desease..but i don't know!I don't feel pain or anything else.And i can see this bending to the left since i 've had my very first erection. p.s do man in general have a penise which bents a bit?I mean,is there the perfectly straight penis?

You are normal. Perfectly straight exists only in the realm of Euclidean geometry. MG

I was diagnosed last month with Peyronie's. I have a lump the size of a pinto bean near the head of my penis, on the underside. Erections are somewhat painful, with a tight, almost burning sensation at the location of the lump. And the shape of my penis has been altered - there is a dent on the left. It seems to me, too, that it's slightly smaller all around -both in erect length and width. I'm 42 and this happened quite suddenly. Anyway, I'm just writing to share my story. It's a profoundly upsetting situation. While it's not cancer or heart disease, it definitely impacts my life. I'm not interested in sex, for one thing. And I feel uncomfortable with my penis, almost like I had a transplant and have some other guy's penis on my body. It doesn't feel or look familiar. I have noticed, too, that the sensation has become dull. Sex no longer feels good like it used to. So given this, and the pain during erection -which is minor, more of an irritation- my interest in sex has plummeted. I don't like to think about it because it's depressing to realize this has actually happened to me. And there doesn't seem to be anything I can do about it. My doctor told me it could clear up but most likely would not. It could also get worse but hopefully will not. In other words, oh well. Sometimes I try and think positive about the good sex I was able to experience in the past. But instead of comforting me, this just makes me sad. I am somebody who accepts new challenges and works hard to be positive, but this has me stumped. No pun intended.

Thank you for sharing your experience - loss of intimacy and alteration of self image can happen in PD. MG

In February of 2005 I was diagnosed with Prostate cancer. I underwent internal and external beam radiation which resulted in blood clots in my urine. My urologist removed the clotting by inserting either a catheter or something else to get to the source of the bleeding in by bladder. A catheter then was left in and then removed a day later. A few weeks later I had an erection and there was a 45 degree upward curve. I went in to see him and he didn’t detect any scarring and then induced an erection to confirm the degree of the problem. He said surgery was risky and put me on a steady diet of Cialis and told me that continued intercourse would help more than anything. I got a second opinion and he said try Vitamin E and more or less agreed with the first opinion. A year has passed and things got better. The curve started to straighten out and I thought I was out of the woods. It still was somewhat curved but the length had improved and intercourse was getting much better. I stopped the steady diet of cialis and vitamin E. Then the curve went the other direction bending downward about 70 degrees and the length is shorter. Do you think the trauma of the bleeding may have caused this or possibly the catheter or the radiation and what would you recommend at this time

Both the catheter and radiation implant can be associated with PD. Perhaps resuming the maintenance therapy with Cialis would give you additional improvement. MG

I'm a 41 year old male and in the last 2 years i have noticed a thinning in the middle of the shaft of my penis. It's mostly when I'm erect. It's not painful and easily corrected (by lightly stretching the area with thumb and index finger.) I notice it much more in colder temperatures and mostly when an erection is beginning . The skin in the middle becomes very tight and wrinkly and the complexion somewhat darker than the rest of the penis & this is when the hourglass shape is at its most severe. Like I mentioned after some simple manipulation the skin loosens up and its not a problem , nor does it impeded any sexual function...but it is a bit troubling in terms of it appearance at times.... Is this a form of Peyronies ?

If the hard erection itself is not misshapen, I don't think this is PD. MG

I know this is going to fly in the face of several folks who have had different results, but I was diagnosed with PD about a year ago. Symptoms had been coming on for about six to nine months before that. Its pretty severe and I am 49 years old. My urologist prescribed topical vreapamil. I have stuck with it. True, insurance didn't cover it, but I gladly paid the bill. Its been a year and there has been a progressive improvement. Not my "old" self, but after being unable to have intercourse for several months, I can now. I don't know for sure if vrapamil did it or not, but I am not complaining.

That is certainly worth reporting. MG

im 18, got peyronies, got it bad, 3 large plaques, 2 under the head on the sides and one mid-shaft on the top. Now ive read everything on the internet, gone to urologists, heard about it all and I only want one thing. I want a cure, a complete cure, I want these plaques out. Now I dont care where I have to go and who I have to talk to, or how much I have to pay, this is the only thing I want in life, a cure. Nothing else. So starting with you, any hints? any idea who the best urologists in the world are? what the best treatment is? anything.

The good news is, at your age there is a good chance this problem will eventually resolve. The bad news is that there are no simple answers. MG

I developed pd approximately 1 year ago. It started with a small lump, accompanied with pain during erection. but no bending of the penis. Then about three months ago, I developed an extreme bending at the lumps. More than 45 degrees, over night! My urologist told me not to waste my time with vitamin e, he said it doesn't work. Do you believe that vitamin E does any thing to help pd?

There are theoretical reasons why vitamin E should help to stabilize PD, but there is no evidence it lessens bending any better than placebo. MG

After a couple months of painful erections and the development of a severe curve in my penis, I went to my physician and was told I have Peyronies. He suggested vitamin E and we discussed surgical options, but I had no improvement over the next several months. The most difficult part for me was waking up during the night with painful erections. During this time my wife started taking a nutritional supplement called Reliv (these are patented products by a company traded on the NASDAQ, so this isn't a scam product). She had Parkinson's Disease, Sjogrens Disease, pain for 20 years from 2 accidents, chronic insomnia, severe ulcerative colitis, and other conditions. Within a few months on the products she had relief from every condition, including the Parkinsons' symptoms gone and off medications. She became a distributor for Reliv and to support her I started the nutrition. I hoped to get more energy and sleep better, but NEVER considered this helping the Peyronies. To my astonishment, after 1 month on the Reliv, I was not waking up with painful erections any more. Over the past 5 months, the pain has not returned, the curve is lessening and my penis is beginning to lengthen during erections. This has been a God send for my wife and I. We love to tell people about the great results we have had with our health.

Very interesting. MG

I didn't even notice it myself until once during intercourse I realized that my penis was not the same "straight guy" he has always been. I said " I don't remember my penis being bent this way". We subsequently realized that some problems I had been facing in the last few months had been a predicator to this event. My doctor had no helpful insights and I left feeling less than confident. Today,having experienced yet another frustrating lovemaking session where the pain prevented the ultimate act (although simply being naked with my wife is pure joy) I decided to search the internet and found your sight. It was actually very comforting to find you described me as the "typical" man who experiences this disease and that the pain eventually subsides. I can live with the distorted penis....it's close to the direction I always wanted anyway....but being able to have an erection without the pain is perfection!

Most men with PD don't have such severe bending as to completely prevent intercourse, and the pain usually goes away on its own. MG

My fiance has PD with an almost 90 degree bend downward; for the length of time we have been intimate I've been developing reoccuring bladder infections - could his PD be a major factor in this? And are there any other internal risks for the female partner?

PD bending may cause urethral irritation during intercourse and resulting bladder infection, but there are no other risks to the partner. MG

In Jan. of 2007 I had a cystoscopy to remove a kidney stone in the right tube. I was in the hospital and put under general antisthiec while the procedure was preformed. After a few days home I had an erection of the penis to find it had a probably 60 deg. Bend to the left and up. The penis was not as hard as normal and would not stay errected for long. I found it very very difficult to have sex anymore. I went back to my Dr. who said I had damaged scar tissue which can be felt along the shaft. He said it was called peyronie's Disease and not to do anything for a year. He also told me to take vitamin E for it. No exclamation of why this happened. I am finding it harder and harder to live with. I am a male 59 years old. Do you think the cystoscope had anything to do with the damage to the tissue. I had no problems before.

Urethral instrumentation, such as a catheter or scope, can produce PD. MG

For those of you who have been at this awhile, is there a foundation that actively lobbies for governmental medical research for our condition? I have spent some time on the Internet and have not come up with one. Also, there does not appear to be any clinical trials. If the answer is no, I would like to start a foundation that would lobby for medical research. (I would be willing to fund the startup expenses, such as the legal paperwork). This is the only way we will ever make progress. Verapramil does not work (I know from personal experience) and I am not optimistic about AA4500. I work for a government agency that funds research and I know that nothing happens without money and Congressional pressure. We would have to start from square one. If we can get this started the next step would be to raise money and get a lobbyist. Maybe a fundraising website.

This would be beneficial - there is good basic research to be done, much of which would apply to other medical conditions involving abnormal scarring. MG

2 years ago I noticed mild pain in the shaft. This has been followed by progressive curvature. The pain persists, not worse during erection, slightly worse with full bladder in AM which lessens after urination. Can pain last this long in PD?

Yes, although it is uncommon - pain usually resolves after 12 -18 months. MG

21 yr old student, long distance relationships during the school year leads to a lot of self-stimulation. Now, I know you've mentioned that masturbation doesn't lead to PD, but I can't help but notice how the curvature matches the technique (although that could just be technique matching the curvature). Anyways, I have no hard lumps, but have noticed changes in all three dimensions... curved upwards, to the right and rotated on its axis to the right (I haven't seen anyone else note rotation so it kind of has me concerned). I've noticed the curvature for a while (especially last year or so) and it appears to be getting worse... I'm guessing a possible reduction in self-stimulation (or perhaps stretching the erection in the opposing direction) with the addition of vitamin E (topical or oral?) might be my best course of action at the moment?

Sounds like you are doing the right things. I don't think you have PD. MG

How do you distinguish between Mondor's disease and Peyronie's disease. Does Mondor's also cause a hardening of penile tissue, and what treatments are available?

Mondor's syndrome is hardening in dorsal veins due to local blood clots and/or phlebitis. It is self-limiting, usually treated with aspirin, and does not cause scarring or bending. MG

Earlier this year I had the Nesbit procedure to correct congenital curvature. My reconstruction urologist recommended that I also have penile lengthening to compensate for the shortening. Due to penile instability problems as a result, I am now thinking about having the penile suspensory ligament(PSL) repaired to stabilize my erections at the base and maintain an erect penis during intercourse. My question is would PSL repair cause neurovascular problems? Would I have problems with blood flow, leakage, maintaining an erection, nerve damage or loss of sensation, etc? Do you recommend PSL repair?

Repairing the PSLcould cause neurovascular problems. I have no experience with this procedure as I do not perform penile lengthening. MG

i have peyronie's and there is a lack of research. I started a web site so hopefully we can get something postive going. i would appreciate if you could mention it on your site http://letscurepeyronies.blogspot.com/

OK. MG

I was diagnosed with a mild case of peyronies about 4 years ago. I have no curvature, but sometimes after climaxing, in cold weather, or after bowel movements the center of my penis retracts while the tip stays full. It feels like a sack filled with water at the bottom. Any insight on this so far? I've actually been able to adapt very well to it. I have a great sex life with my girlfriend. After learning more, I began to gently squeeze the tip of my penis in order to push the remaining blood at the tip of my penis back out towards the body past the mid point where the scar tissue is. It sometimes helps return my penis to normal shape when the peyronies acts up. Could this gente squeezing of the filled tip be any harm or cause any damage?

I'm not sure what this is, though it does not sound harmful. MG

I have had Peyronies for almost 2 years,length and girth size is reduced and a 45>degree upward angle has developed.I am 60 yrs.old and also need to use Viagra now. Would it be possible to take 360 mg.tabs of Verapamil and 0.6 mg. of Colchicine and supplement with Vitamin E 1000 IU at the same time on a daily basis.I suffer only a small amount of pain during intercourse but more afterwards.Most of all it affects my relationship with my wife and my future outlook on sex in my future age.

Oral verapamil has not been shown to produce high enough tissue levels for therapeutic effect, so I would eliminate that. Everything else seems OK. MG

 

October 2007

I have had a firm pea-sized lump at the very base of my penis (close to the pubic bone) for over 15 years. It is very mobile and I can even hold it between 2 fingers. It appears to sit on some kind of hardened vessel. At the time it was dismissed as a cyst. 6 months ago I noticed a second lump right beside the first one, which was again dismissed as “nothing”. A month ago I noticed a third lump (same size) in the shaft, which seems to be in the right corpus cavernosum. Again there is a swollen vessel leading to it. It is painless and there is no curvature or erection problem, but since a week ago I suffer mild diffuse pain in the right groin and renal region. Could it be Peyronie's?

Sounds more like superficial vein thrombosis than PD, though an evaluation by a urologist would be a good idea. MG

9 months ago I had the Nesbit procedure done to correct a downward curvature. All sutures have buried themselves except for two(suture knots) which are causing discomfort and skin abraisions during intercourse. They are located dorsally but one is at the far left and the other is at the far right of the penis midway along the shaft when erect. They are placed symmetrically to one another and are very much at the surface of the penis just under the outer skin. I was told by a local reconstruction urologist that these two suture knots are located very close to the nerves and said that I could lose sensation if the sutures were removed. He fears that if he were to remove those sutures and replace them with absorbable sutures the curve would probably return a few months later. He also confirmed that I do not have suture granulomas. My problem is also causing discomfort to my girlfriend during intercourse because these two suture knots feel like two small hard pieces of stone that stick out beyond the normal profile of the penile shaft when in the erect state.

The fact that these sutures are located laterally on the shaft (off the midline) suggests to me that not a lot of dorsal neurovascular mobilization would be required to expose them. Your doctor is correct in that the use of absorbable sutures can be associated with recurrence of the original bend. If they are persistant and bothersome, they could probably be removed and replaced in inverted position (knots buried), though this would carry a slight risk of sensory loss. MG

I am a 54-year-old diabetic. I was curious about an odd curvature of my penis upward during erection, and my doctor examined me and immediately diagnosed my problem as Peyronie's. I've also been suffering from ED for about a year or so that has been spotty in its response to prescribed ED medications. The doctor recommended a regime of Vitamin E. A couple questions that I should have asked him, but I hope you will be kind enough to answer: 1. I had been having severe blood sugar problems for about six months that seem to be improving. Will an improvement in my blood sugar effect a lessening of the Peyronie's symptoms? 2. How effective is Vitamin E? How much should I be taking daily? How soon might I possibly see any effects from it?

As there is a known relationship between diabetes and Peyronies disease, improvement in glucose control would be a good idea. Vitamin E is a standard reccommendation - it will probably not reverse the condition but may help it to stabilize. MG

I'm fairly sure I have PD, I had a gentle curve to my penis all my life but in the last 4 months I noticed an increase in this and I'm really freaked out. I have an appointment with a urologist in 1 month and I estimate this has been "condition" for about 3 1/2 months. It 1 month too long to wait to retain the best chances of reversal and recovery? Should I start Vitamin E on my own ? if so what dose? As far as treatment, recovery goes are their any preclusions for, HIV+?

It certainly wouldn't hurt to start vit E (400 units daily). 1 month would not be too long to wait. HIV status will not affect treatment. MG

I am a 27 yrs old male, with very good physical condition. I am an unmarried person, and so far I don't have any physical relationship in my life, till date I am virgin. Three weeks ago every thing was normal with me. I was having proper erection in my penis, and use to have masturbation twice in a week. But in recent 2 weeks I am not getting any erection, as well as no any desire to masturbate. I am not putting any stress to masturbate or ejaculate.. waiting for natural cure. I have not faced any physical problem in recent few years.. Nothing is wrong with my other part of body.. I am very much particular about my diet and workouts too. Only one thing which may be psychological, for my higher education I am staying in abroad, away from my parents for last couple of years, and unable to visit them in last entire year.. From last 6-7 years I have noticed one thing, my entire penis ( not only tip) is having some curve towards left, when its in erected position. I am not sure is it erectile dysfunction or not? But I found on Internet, such a shape of penis is not that uncommon, may be due to masturbation there is slight curve..I am not sure is it erectile dysfunction or Peyronies disease. So far I have not been to any doctor regarding this problem, but planning to visit an urologist soon. Please could you advice me, do I really have any problem or it's just psychological problem.

I don't think you have Peyronies disease. MG

Why can't orthoscopoic or laser procedures be used to correct curvature?

Because they don't address the problems created by PD. MG

I have been diagnosed with PD but am wary of the urologist who reached this conclusion. There are no lumps. However, under the surface of the skin is a ribbon-like hardness about one-half inch wide that runs along the top side for the full length, from within my body up to the glans. A blood vessel that lies on top does not seem affected by this. The curvature is gradually upward for most the length of the shaft at approximately 45 degrees. It developed overnight. It was fine one day, the next day was this change. That first erection was mildly painful for one minute or less, but there has been no pain since. Instead, there is a slight pulling sensation; the girth is diminished and the length has shortened by about 1.5 inches, 50% of which was immediate. I am 60 years old and this condition began 9 months ago. If this is not PD, what else might it be?

Sounds like PD to me. MG

I was just diagnosed with PD after sustaining a sex related injury to my penis about a month ago. I went to a urologist who recommended vitamin E and a wait and see attitude for 6 months. I'd like to be more proactive and so began taking neprinol and vitamin E today. I have a small bump on the top of my penis but no noticeable curvature. There is some pain having intercourse. Is this an aggressive enough course? Is there any downside to going this route?

There is no good data on the effectiveness of vit E + neprinol. A more agressive course would involve injection therapy, either verapamil or interferon. If you want to stay with oral therapy, I would consider adding colchicine. MG

Is there something that will take away the scar tissue that causes the penis to shrink?

No, unfortunately. MG

Several urologists have told me I have a minor cases of Peyronies disease. This is based on the presence of several littles cysts, tumors or bumps in my shaft. They feel like they're in the middle of the penis, virtually in the urethra. The doctors refer to them as plaques and scar tissue. I don't have any noticeable curvature, despite what feel like a lot of plaques. Urinary retention, weak stream, and occasional urinary frequency are my most persistent and bothersome symptoms. Recently, urine has come out in a split stream, as if the urine was navigating around an obstruction. When I urinate or ejaculate, I get the feeling that the urethra is not quite empty. I have to strain and push to get the rest out. I have experienced similar sensations during masturbation, accompanied by an excess amount of preejaculate. I recently felt a burning sensation near the head of my penis when I urinated. Do you think I have Peyronies disease, and does PD often interfere with normal urination?

Peyronies disease will not affect urination. MG

I was diagnosed at 35 with PD. Erections were somewhat painfull and there was curvature. Soon after the pain went away. Since it did not affect my sex life my doctor said that treatment was not necessary. I just turned 50 and recently I have noticed that the curvature is much worse, aprox. 90 degrees from right to left. There is also an indent so my penis has a twist to it. I can still have sex with my wife without any problems, but the disfigured penis bothers me. Coincidentally, I am being treated for Rheumatoid Arthritis. The RA (if that is a correct diagnosis) just started last year. At 35 my doctor said I was young for PD and now my Rhematologist says that I am young RA. Could there be any connection?

Yes, this is quite possible as both disorders can reflect an abnormal immune response to your own connective tissue. MG

My penis is bent slightly to the right, about 20 degrees. The problem is a very prominent indention on the left side near the base of the penis. It is about 3/4 inches long and appears to take up the full width of the left corpora cavernosa when erect. Is it possible to remove the plaque and return the penis to it's original condition. If removing the plaque also removes the sponge material that swells with the blood flow, are there any sponge material that can be used as a replacement. If this is not possible, please tell me what the best treatment is.

It depends on erectile function: if it is very normal, graft procedures may be able to restore diameter in this area (plaque incision or removal does not remove the spongy material). If not, implant surgery may be a consideration. MG

This is going to sound weird, i just saw a program on Tv about Peyronies I'm 15 years old and my penis is curved when errect, and sorta points to the left about 10-20 degrees The curve is quite visible if looking in a mirror. I've noticed this since i was around 12-13 i think.. Do i have the disease and if so go to the doctors but i am quite shy and don't want to get my penis out if you need proof i can do a paintshop exact drawing of how it curves Thanks alot please email back, i want to have children when im older.

You don't have PD, and this won't stop you from becoming a father in the future. MG

 

September 2007

I developed Peyronie's Disease about 10 month's ago. The urologist first said vit-E 1200 IU for 5 months no resalts so I could not get the verry price Topical Verapamill. So next thing was the Verapamill injections 6 spread out over two weeks a part not knowing what to expect my first problem was the pain of the shot's - one a local anestices then 2 shots of the verapamill then I got up and found my self on the DR.'s floor only to find out that that stuff do's that to you. Then came the swelling and black & blue penis with a lot of pain the only thing that helped for 5 days was a ice pack on and off thru the day I would like to think some one could have prepared me so I am letting any one that is thinking about this treatment I have 5 more visits now I am glade that I did not spend the money on the Topical Verapamill I so far have not read any one that had any resolts so mayby the injections will help I will keep you posted.

Please do. MG

I have just recently bee diagnosed as suffering with PD. I am capable of having an erection and normal sex is still possible. I am cocerned about treatment options and becoming impotent for rest of my life. What are the statistics on that for each surgical treatment option?

Peyronies disease is not likely to make you impotent. The chance of significant erectile dysfunction following surgery is about 3-5% for a plicataion procedure, and 10 -15% for a graft-based operation. MG

I distinctly remember being normal before a circumcision and having a severe downward curvature after. I had the circumcision when I was 7-8 years old. At the time I did not care about the significance of my problem. It never struck me as being abnormal until I was older. It pains me to think that had I notified my doctor, something could have been done it at the onset. It's now 11 years later (Im 19). I have never had any pain or discomfort while being erect. I have a fair amount of flexibility (no pain until bending it in literally the other direction). I was wondering whether I'm suffering from PD or congenital curvature. I have some flexibility and can't really feel any scar tissue (what is it supposed to feel like? Is it visible?), so I thought it would be the latter, but the curvature is pretty severe (90 degree pretty much) which might indicate it is PD after all. Another point that might support PD is the fact that it occured after surgery... I'm guessing scarring is a possibility in that sense. I've never slept with anyone... so I don't know whether sex is even possible in my state. Since I don't know, I'm weary about surgery--are there any statistics on what chance I have of getting postop ED?

Removal of excessive skin from the underside of the penis at circumcision may produce downward bending. This does not sound like PD. Correction of congenital curvature with plication at your age carries a very small chance of ED - less than 5%. MG

About two years ago (age 45) I had a penis I was satisfied with. One morning when I woke up and sat at the edge of my bed, I leaned over to put my slippers on. At the most bending of that action I felt a painful stinging snap at the base of my penis. About a minute later it subsided, and I shrugged the event off. A few weeks later, or perhaps a month or two I noticed my penis was not looking the way it always had. Larger at the top (before the tip), and thinner at the base. Slight ache to it too. A few months after that I was astounded to notice a bend, not to one side, but upward, almost at the half way point. and even still thinner at the base. The pain, or rather ache was no more, but the misshapen bend was accompanied by in and out valleys along the sides, as well as much shorter then it was before this happened to me. Doing a lot of online reading I came to understand Peyronies, something I never even heard about befpre. I was so disappointed in this day of medicine there was nothing that significantly helps, other then surgery that can straighten the penis, but not regain length. I have heard about shock therapy, pumps, etc. I have read all about Vitamin E, Poba, and many more, but always with the added lines there is no evidence to support their effectiveness. How frustrating. I have read your entire list of answers to others. I was hoping perhaps there was something you may have heard, or perhaps your own theory as what might help, that you haven't written about before. For instance, on the market now there are scar treatments to soften, or breakdown and fade away scars. Topically used on the penis, absorbed by the penis, in your professional opinion would you think this may soften the scar tissue within? For me, surgery is not an option, I just would hope there was something that could breakdown a fibrosis tissue type plaque.

At this point one of the most promising medical approaches is nearing phase II clinical trials: intralesional collagenase. This drug has been proven to break down plaque tissue, and the question is, just how effectively can is correct bending? MG

Does Peyronie's disease stop the growth of your penis? If so, will curing Peyronie's initiate remaining development?

It is not known to stop the growth of the penis. MG

I am a PT and routinely work on patients to break up adhesions and scar tissue. My new boyfriend has recently (4 mo) developed PD. Can some type of gentle manual therapy aid in breaking up the plaque of PD? Also, if the initial stages of inflammation in PD can cause the laydown of scarring in the tissue, is there any benefit to systemic anti-inflammatory agents/ herbs or anti-inflammatory diets?

This may be of help, as preliminary data suggests traction / stretching may lessen curvature. Anti inflammatory medications have not proven helpful in correcting deformity, though they will lessen pain. MG

I am in my early 20s. I have about 35 degrees bend to the left. My base on the left side feels soft during an erection. During maximum erection, right side becomes properly erect and rigid but the left side, again mostly at the bottom, remains only mildly rigid and penis gets bent there easily. I have some problems in masturbation. It takes long and I loses it fast if I take my hand off. I have not had any sexual intercourse yet. My night time erections are again bent and semi rigid. I always get semirigid spontaneously but have to stimulate hard to get rigidity and ejaculate. I have no pain and there is no palpable scar. Do you consider it as Peyronies?

This sounds more a vascular / congenital problem than PD. MG

I am 32 y/o and I've had a slight curvature for as long as I could remember. It curves upward and left slightly when erect. I have no bumps or pain. I've only heard women complain during sex during certain positions. I am not sure if this is congenital or PD. It doesn't bother me too much but I am worried if it is PD can it get worse?

You don't have PD, so don't worry about it. MG

Ever since I was 13 I have had a cuvature to left of about 30%. I think I can remember a time when I first started masturbating that I may have injured my penis and that may have been what caused it. But this was so long ago that it is hard to remember, (I am now 28). As far as I can tell there is no calcium deposits anywhere in my penis. I cant find any hard lumps. I have allways been embarrased of this condition and wanted to do something to correct it. From my research it seems like maybe the Nesbit procedure would probably be the best route. I have been doing some research and I found some stories of men who have had this procedure done. They said they lost a lot of length from the procedure and that sometimes after a couple years their penis went right back to its origal curvature. Is this true? How much length could I possibly lose and what are the chances of my penis going back to its original curvature? Also I have heard that sometimes after the procedure your penis will be staight during erection and curved while placid even though it was never before. Is this true?

Average length loss from Nesbit is 1 -2 cm. Return of previous curvature is very unlikely if permanent suture material is used. I have never heard of this procedure causing curvature of the flaccid penis. MG

My partner has developed a twisted penis since our last sexual intercourse. It's twisted to the left and the opening on the gland is now horizontal during erection. He says that it doesn't pain and it's now three weeks since it's still twisted. What would you advise him to do about it and is it a particular disease?

I'm not sure this is PD, but it might be a good idea for him to see a urologist. MG

I'm 54 years of age and three weeks post lue procedure for a 90 degree upwards mid shaft bend. I've suffered very painful early morning errections but am pleased that my penis now appears quite straight. It is however a bit lumpy. I gather I also had a couple of plication sutures more distally on the underside. My greatest concern is that since the op, my glans penis has no sensation at all. Whilst this is difficult to assess on ones self, I've tried touching it with a cold metal spoon, both on the shaft and then the glans. The shaft feels the cold but the glans feels nothing. My surgeon said (at 2wks post op follow up) that it may be due to contusion of the nerve but only time will tell. 'Come again in six weeks'. Is this normal and might it be permanent? If permanent, I feel I've jumped from the frying pan to the fire and suffered for nothing. I've also noticed that the length and girth are much less than they were before the op. It was about 8 ins prior to the PD and a girth of 5.75ins. Whilst I haven't measured it yet, I'm sure it's about 2.5ins shorter and much less thick. Again, is this due to the short term internal trauma and will it recover, or will it be permanent?

The lack of sensation in the first few weeks postop is worrisome, though nerves take a long time to recover. This soon after surgery the length loss is at its worst - you may get some of it back, though a loss of 2 -5 cm after repair of a 90 degree bend is not unusual. MG

I spend a lot of time working on my cars and I vaguely remember a slight pain or pinch in my penis as I was laying on my stomach across the engine compartment while my penis was smashed against a sharp edge of the fender. I never thought much about injuring my penis in the past because it didn't seem to hurt at the time I was doing it. I'm thinking that I may have damaged it in the past and this could be scar tissue of some sort. I read in a previous post that Induratio Penis Plastica ("IPP") is another name for PD. Can you have PD without any bending? Is that what IPP is? Could a pinch to the penis cause scar tissue like this? I made an appointment with a urologist, but I can't get in for weeks and now I very disturbed, because I've been reading posts on the Internet about secondary penile tumors and it's terrifying me.

Yes you can have PD (or IPP) without bending. See the doctor but don't worry about tumors - I have never seen one in 25 years of treating men with PD. MG

sometime ago i began rubbing aspercream on the penis,scrotum and along each thigh . i will tell you categorically it has significantly shrank the effect of peronies and has resulted in a fuller erection, not completely back to normal. i have never had a reaction but someone else should not rush into this.it is not as far fetched as it may sound. this rubs are designed to increase blood flow, stimulate the area and increase sensitivity.. another possible rub is ky warming gel.any medical data on this

Interesting - I have no data on this. MG

my boy-friend was just dyanose with Peyronies. His Dr. said he should medication. We are getting married very soon and always spoke about expending out family. How much or how little of effect will the medication have on us consiving. Also I think it is starting to mentally affect him as a man.

Peyronies disease will not hurt his chances of becoming a father, though he should not use colchicine. You can help him feel that he is still a man. MG

I am 57 and was told 20 to 22 months ago I had PD. I have plaque at the base of my penis on both sides and I turn upward 35 to 40% and don’t have any pain and can still have intercourse. My question is after this length of time is the condition unless stable or can I expect it to get worst?

It would be very unlikely for your condition to worsen, based on the duration above. MG

I am a 48 year old man who had surgery for PD to straighten the penis, the doctor said the plaque buildup cannot be removed, however I am upset that there is (Guitar strings) inside the shaft to straighten the penis and after all that the surgery performed in June of this year did not do the trick....the sensitivity is unbearable........I was told I could resume a normal sex life after about six weeks, I think I am losing my mind, If I don't keep gauze around the head of the penis the sensitivity is so annoying I feel like ripping it off............. are there support groups for after PD surgery? I know I am not the only one with this problem..... Maybe if I talk to people who has had this surgery I could understand more clearly about this devistating disease some men get, and no wonder we pray for death.

This hyper sensitivity should gradually disappear. I believe there is currently a support group - check the Peyronies advocates web site. MG

I believe I may have Peyronie's in the early, inflammatory stage. I do not want to wait a year or so and run the risk of it getting worse. I read that the early damage caused by Peyronie's is possibly reversible. If this is so, what should I take in the way of medication in order to accomplish this?

The standard choices in oral medications would be potaba, colchicine, and vitamin E. MG

I'm a 52 years old, this disease starts on my penis 4 years ago with a little hard scam inside, now it has around 1.5 in by .5 in my curvature is growing, I spend 1 year taking Potaba 500 mg on the daily basis but do not stop the progress. Q What can I do? Q Exist some kind of surgery?

After 4 years, surgery may be the most effective course, depending on how bad the bend is. MG

August 2007

My husband got PD in 2004 at the age of 48. At that time the tip of his penis bent 90 degrees to the left and intercourse was too painful for him. About a year later he had some body work done and his penis straightened out, however it shrunk significantly both in girth and length. He does not get very hard, and though you write that the quantity of ejaculate is not part of PD, it seems that his ejaculate is greatly reduced. He has been in denial about this for the past 4 years and we have had no sex life at all. I am sad and frustrated beyond words. He is diabetic and has not been great about maintaining his sugar levels (he was hospitalized this year for a staph infection that began with an ingrown toe nail), he has Hep C, and I think he has Dupuytren’s contractures based on what I read on your site. Do you think he could survive the risk of surgery his vascular system being what it is? And do you think an implant could successfully restore length and girth to his penis?

Implant surgery works well to correct curvature and restore function lost to erectile dysfunction (impotence), but it is not very effective in restoring girth or length. Also, in light of your husband's problems with diabetic control and infections, implant surgery could exposed him to dangerous risks such as infection or tissue loss. I would recommend he try a vacuum erection device and phosphodiesterase inhibitor (viagra, levitra, or cialis) in combination. MG

i masturbate from childhood .now um university student .um fed up by this habbit.and cannot left it.penis normal size is 2inch .in elongation it is 4.0 inches .it is downwaard curved shape and broken from mid internally .and easily can be molded. urethra length is fixed in normal case or in erection .i am not in aposition to satisfy my partner in future .upper skin of penis is loose but urethra does not allow it to extend more. ihave a headache for 7 years .digestion problem .sleepness disorder, memory is disturbed .ifeel like an abnormal person .my parents ask me to do marry .but i refuse. testes are also of undersize .um too much anxious about size and curved shape .is it peronies or something else so what is this

The downward curavature sounds congenital - see a urologist with experience in this field regarding corrective surgery. MG

I have had Peyronies for about 18 months and have lost at least an inch in length. Is there any known way to regain this length?

Not at present, though studies are underway to examine the use of physical traction (stretching). MG

I am a 14-year-old male, and have had a curvature to my penis for as long as I can remember. It bends about 8-12 degrees to the left when erect, and there is no pain or discomfort. After learning about Peyronie's disease, I searched the Internet for information on it. I am now pretty sure that it is not Peyronie's disease, and that it is either congenital curvature or hypospadias. I don't really feel comfortable talking about it at home, because I live with my mom. Would it be best for me to talk to my pediatrician, or to a urologist, or to just take a lot of Vitamin E? Also, would masturbation have any affect on the curvature, such as causing it or increasing it?

Yes, talk to your pediatrician, who will probably refer you to a urologist. Masturbation will not cause a problem. MG

I am 70 years old. My cholesterol count has been high since I know about this apparent (the medics like to call it) decease. Last year I finally gave in to the standard statin treatment. Since I’m healthy I never understood the need of taking drugs for something which doesn’t bother me at all. After a few month of taking the drug PD developed, at first a little curvature to the right plus some plaque on the penis shaft. As well as some plaque developed in the palm of both hands. A few weeks ago the curvature became upward; the erected, very hard penis touches my(flat) stomach. My wife got sore from sex and refuses further activities. In your forum I noticed a few descriptions of similar side effects. I want to quit the statins and see what happens.

This sounds like a good idea, though I know of no data linking statins to PD. The relationship to your hands (dupuytren's contracture) is real and suggests your predisposition to PD is genetic. MG

I am due to go into hospital for surgery to correct the upward bend of my penis caused by PD. I have also heard of a treatment using ultra-sound which can be carried out, is this correct? The other question is on average how long is the recovery period after surgery.

Ultrasound does not have much effect on curvature. Most surgery for PD allows you to return to sexual activity withing 4 -6 weeks. MG

I have moderate Peyronies disease, with a 30 degree upward curvature. I do experience pain with intercourse. I have been placed on topical Verapamil. Is it safe to take oral Potaba while on topical Verapamil?

Yes. MG

1. Are there any resources for finding a urologist with expertise in treating Peyronie's? 2. A urologist in Canada promotes the treatment of Peyronie's with extracorporeal shock wave therapy, which he states was originally's developed to treat kidney stones (lithotripsy). Is this an effective and preferred treatment and is there risk of tissue damage?

Scroll down the forum to find referral resources, such as the association of Peyronies disease advocates. Shock wave lithotripsy has been shown to be ineffective in at least one meta analysis (data combined from multiple studies). MG

I am a 60 year old man who was treated for prostate cancer 2 years ago. I had seed implants plus radiation. Since that time erectile function has declined to the point that Viagra, etc. produce inconsistent results. About 3 months ago I began using Edex injections which work very well. During the exam for the Edex the doctor noticed a lump at the base of my penis that he diagnosed as Peyronie’s Disease. I had only been aware of this lump for a month or two before then. Since that time the hardness has progressed to the a strip about a half each running along the length of the top of my penis. I now have about a 30 degree upward bend and experience minor discomfort when having sex. I fear it will get worse. The only trauma I ever had in that area was the catheter that was in for 24 hours after the seed implant and was very uncomfortable. I asked my doctor about discontinuing glaucosamine which I have used for 10 years but he said it was not necessary. He also said that I could continue to use the Edex. He implied that injections for treatment were easy and very effective and advised me to wait to see how things progressed. He never mentioned vitamin E or any other preventative measures. I have a number of questions; Is there any relationship between PD and prostate cancer and/or radiation treatments? Could the catheter have caused trauma and the symptoms not noticed for over a year? Should I continue to use the Edex?

There is a known relationship betweeen catheter placement and PD, as well as radical prostatectomy. Radiation itself is not know to cause this disorder - it used to be used for treatment. I would reccommend using a vacuum erection device rather than the edex injections, as most authorities feel the continued use of injections may contribute to the progression of PD. MG

I recently had to be catherized in Er because of inability to urinate because of a swollen prostate. I now have developed about a 40% bend about two thirds of the way up the penis. It has happened very quickly. Could there be a connection to the catherization?

Yes this is possible. MG

Is it possible many spontaneous remissions of PD are actually other conditions with similar symptoms? Old literature (even some recent) reported 50% spontaneous recovery. Now most reserch cites 5 - 15 %. I am thinking, with better diagnostic techniques, might this number drop even more approaching 0%? Is there any objective evidence for spontaneous recovery of confirmed PD?

Spontaneous recovery from PD is very uncommon, especially if the deformity is severe (>60 degrees). The majority of cases reporting "spontaneous remisssion" describe resolution of pain, not bending. MG

I had a tumor removed from spinal cord about 3 years ago and it is neccesary for me to take Viagra. Approximatley one month ago I had a sex which lasted for 5 or 6 hours (on and off). It is hard if not impossible for me to ejaculate so the sex went on for an extended period of time. I have not had an erection since (so about 30 days) until yesterday and thier was a serious curveture in my penis and it would not get fully erect. I have noticed some rigid bumps along the top of my penis around the base. I was sore for several days afterwards but did not experience a loss of erection during sex. I didn't even notice anything was wrong until yesterday. I do now notice when I feel around the bump that it is somewhat tender.

I would suggest you see a urologist, as this sounds like PD. MG

Where can I get information about any connection between PD and Atenolol?

There have been reports on the association of beta blockers (the class of medications that includes atenolol) and PD. A search through the national library of medicine for these key words should help you locate them. MG

I am the webmaster of the Peyronie’s Disease Institute website, at www.peyronies-disease-help.com This is an Alternative Medicine website that offers a holistic therapy concept for the management of PD. Currently, this website lists your organization on its forum directory page. You may view your link on our website at http://peyronies-disease-help.com/peyronies-forum-directory.html My medical colleagues and I request that you extend the favor to include a link on your website to the Peyronie’s Disease Institute. Here is an example of a brief description you could use for this co-linking arrangement: Peyronie’s Disease Institute – Alternative medicine website offering Peyronie’s disease holistic treatment options.

Thank you, I will work on setting up this link. MG

I do not see what I thought I might see when I found your web pages..I have had peyronies since 2005 after I noticed a black&blue on the penis 3 days after a hernia operation..doctors said it could not have been caused by the operation? what I don't see on your site is other people how have had peyronies and have had one of the operations tell the readers of this site if the operations were godd or bad ? Are we at the end of our sex life when we ger peyronies.. or is there so real hopeand good doctors ouit there.. others please answer

I will post replies as they come in. MG

i have had pd now for five years and nothing seems to help. i have tried Neprinol for 2 months now with no results. What do you recommend I do since nothing seems to work. My penis has gotten so small i have trouble urinating since it dribbles down and hard to direct the stream. My father also has had this problem since he was 55 and he's 80 now .My life sucks and getting worse.

Peyronies disease can run in families. If this has destroyed your sex life due to bending, surgery can help. Unfortunately, surgery cannot restore lost length. MG

In 2003 at the age of 62 I underwent a prostatectomy. Of course I was catheterized, and when I awoke from the surgery my first awareness was not of sensation from a surgical incision, but of an achy pain in my penis. During the next two weeks while the catheter remained in place, if I happened to bump the catheter tube in some way I received an instant sensation of pain. A dull ache remained after the catheter was removed. Some time later when I was trying to determine if I had any remaining sexual function, I took a blue pill. My penis would engorge only to just past the mid-point. Over time this went away and my erections (using injections) would be uniform. However----I discovered that I had lost one-third of my original penis length. I didn’t have that much to begin with, just less than six inches. It did seem to be a bit fatter. Just as disturbing (maybe even more so) was the fact that I had lost virtually all sensation in my penis. During my feeble efforts at sex, even if I achieved penetration I could not actually feel anything. Any “enjoyment” of the process had to created in my mind. Is this a normal result of PD? Could the surgery, particularly the way the catheter was inserted, have caused the onset of PD? I had absolutely no symptoms or problems beforehand, although my penis had always curved slightly to the left. When I suggested this possibility to my doctors they looked pained and uneasy (envisioning a lawsuit, I presume), but they never ventured an opinion. My marriage—to a younger woman—is on the rocks as a direct result of the breakdown of this part of the relationship, but I’m resigned to that and the fact that sex will no longer be part of my life. At 66 I can deal with it.

There does appear to be a cause-effect relationship between radical prostatectomy and PD, as welll as between catheterization and PD. Also, prostatectomy can reduce penile length. Usually PD does not afffect penile sensation - this may be related to your surgery. MG

About 2 years ago I was desperately reading through Peyronie's information on the internet. At that point it had just started to effect me and I was instantly panicked and soon overwhelmed by it. I am writing to let you know that for me it has gone away nearly completely. I was desperate like many of you may be and profoundly depressed. How or why did it resolve - I don't know. I am sure a reversal happens more often than is reported. It is likely that most people, if this resolves, do not come back to the internet forums and let others know. DO NOT LOSE HOPE. Take care of your body and mind as well as you are able. Good things happen too and this trying issue can go away - for me things got back to normal after approx 15-18 months. I wish you all the best. It is my belief that these tragic things are often used to have us look outside of themselves. As crazy as this may sound, I am glad for my bout with Peyronie's because I feel it brought me to a better place. For me it brought me back to God. I hope this trying time also leads to something good for you.

Thank you. MG

 

July 2007

I was diagnosed with PD around 1986, something I account to straining myself at the gym. Nonethless, that Dr. in Philadelphia, another in MD, and then a visit to you in the early 90s only confirmed there wasn’t much that could be done. I now see a trial that you’re starting this year and wonder if you could give information on it and who it may help. I also am curious if any of the new laser treatments that are being done to dissolve scar tissue may be a glimmer of hope for us suffering with PD. By the way I was told to stop my vitamin E by a heart specialist 2 years ago. I haven’t seen any noticeable difference without it.

Plans are being made for a clinical trial with collagenase, sponsored by the Auxilium Pharmaceutical Company, sometime in 2008. I will post details as they become available. MG

I've launched an pseudonymous blog about peyronie's disease: http://thebentnail.blogspot.com/ I'm a physician, middle aged, with fairly severe disease. Since I can't do much about it, I decided to work the wikipedia page on the topic and put material that doesn't fit the page into the blog. I'll leave it to your judgment whether it should be mentioned on your site, but I do appreciate your work.

Thank you, I'll have a look at it. MG

I had a robotic prostatectomy performed on 7/25/06. I have not yet had return of erectile function, but some stirrings. I have used an ErecAid VED for about 6 months, and tried injections over the last 2 months (about 19 times total, with success 7 times (PGE1, Bimix and Trimix tried). Did not notice curving when I was only using VED. With the injections, I have noticed curving, pointing down, and a bit of swelling. I went to see the ED specialist at UCLA Urology, and he said there was plaque and an edema, and prescribed Cialis, Pentoxyfylline and L-arginine, no VED and no injections and abstaining from sexual activity for 6 weeks, then subsequent check-up. Is this level of Peyronie's likely to be reversible? Is it normal to stop VED and sexual stimulation activity?

Radical prostatectomy can lead to penile shortening and in some cases, to Peyronies. I would agree with the above recommendations and feel there is a reasonable chance of reversal based on the time course involved. MG

Hi. I am 15 years old and I started puberty in 2006. Is it normal to have a slight curve in ur penis, and is this caused by excessive masterbation because I do it a lot because of girls hitting on me?

The slight curve is normal, and is probably not due to masturbation. MG

I've had Peyronies disease for several years. Last June (06) I started a series of injections with VERAPAMIL and also have taken Vit E orally. It's been 1 year and there is no change - I still have a 45 degree bend and inability for intercourse. My urologist recomended a implant for both the Peyronies and ED. However, he closed his practice and I need to locate a Seattle area.

Please refer to prior entries in the forum for referral resources. MG

Could you please comment on the use of Tamoxifen to soften the nodule of Peronies much obliged

This drug, used primarily in breast cancer for its interference with estrogen receptors, has been used in the treatment of PD though there is no placebo-controlled data confirming its effectiveness. MG

I’ve recently noticed some hard lumps (4 or 5) towards the base of my penis, on the bottom (1), right (rest) and top (1) (as you look down). I’ve also noticed a degree of curvature to the left ( as you look down), the curve commencing opposite the lumps. I’ve seen my GP and he’s referred me to a urologist, but in the meantime, does this sound like Peyronie’s? I’m confused because the lumps are on the opposite side of the penis to the curve. The curve, at present, I would say is around 10-15 degrees.

Yes this sounds like PD. MG

I am a 50 year-old diabetic. I have been a diabetic for 4 years now. I was having problems getting erections for about a year but masturbated anyway. About 8 months ago it became easier to get an erection but I noticed my penis was slightly bent. It has gotten worse and the bend is now nearly 90 degrees. I spoke with my Dr. and he said to take vitamin E. He said a urologist would only suggest the same thing. I take a 1000 IU capsule 2 times a day and have been for 7 months. In addition to being diabetic, I also have been taking Lipitor for 3 years. Could any of these factors be a cause of my P.D.? Is there anything else I can take or do to decrease the bend in my penis? I read somewhere that in many cases it goes away after about 18 months, but mine is just getting worse.

I would suggest you limit vitamin E to 400 IU daily. PD is slightly more common in diabetics, though I don't think lipitor is a factor. Based on the severe curvature you have developed, I would not expect your condition to resolve spontaneously. MG

I have a slight curvature in my penis on the right but it is bent downward ( about 45d) since I started masturbating. I donot have any lumps nor do I feel any pain during erection. I am sure this would be a case of congenital curvature coz this has not developed overnight. Will I be able to have sound sex. I had sexual intercourse with my girlfriend, she did not complain of any severe pains. My penis sometimes slips out of her vagina while we are having sex. Moreover when she sits on my penis (not insertion) with my pants on I feel pain.

45 degrees of downward congenital curvature is usually associated with slight sexual difficulty. If this is the case, you should see a urologic surgeon with expertise in reconstruction to discuss the possibility of a nesbit procedure. MG

I’ve just recently found this website and found it to be extremely helpful. I’m a 45 year old and I’ve had PD for a little over a year now. I went to a urologist in my home town but he was mostly unhelpful. He told me to take vitamin e and then perscribed Viagra, neither of which helped. I’m very interested in the Collagenase clinical trials. Is there a way to volunteer to be in any of this testing?

Probably so - when I have information about the proposed clinical trial, I will post it here. MG

I am 68 years old. About eight years ago I contracted the disease. After about a year, I went through a series of Verapamil injections for six months. There was no sign of improvement. I have a left bend of about 45-60 degrees. I have never experienced any pain. I have trouble having intercourse because of the crevature. I asked my urologist about an operation and his experience. He said he does 2-3 per year. At this point I am uncomfortable with having him do a surgery. I asked him about Collagenase and he showed little enthusism for it. I have not been treated for five years. Would you suggest surgery? Would you suggest another course of treatment? I am in Cincinnati. Is there any goup that has better experience with the procedure or the treatment of this disease?

You are wise to seek someone with more experience. There are resources for referral below in this forum. MG

Hi i think i might have PD or a congenital curve and was thinking about using penis traction to try and correct the curve. I was wondering if you could tell me if penis traction actually works to correct the curve or not?

We don't have sufficient evidence now, but Dr. Levine in Chicago is currently running a study to answer this important question. MG

I've had PD since age 13 and am now 63. I didn't know it was a disease until the Clinton affair, and didn't know it was treatable until now. There was never any pain, only the severe downward bend, which only added to the fun for most of my wild years. The bend has disappeared now, but I've lost a third to a half of my length in the last three years.

I think you probably have congenital curvature. In some cases the curvature can put enough stress on the tissue to induce secondary Peyronies. If this causes scarring opposite the bend, it may actually straighten the penis - but with shortening. Sort of a natural nesbit effect. MG

I am the webmaster of the Peyronie’s Disease Institute website, at www.peyronies-disease-help.com This is an Alternative Medicine website that offers a holistic therapy concept for the management of PD. Currently, this website lists your organization on its forum directory page. You may view your link on our website at http://peyronies-disease-help.com/peyronies-forum-directory.html

Thank you. MG

I am 34 year old and went to my general physician over a year ago with what I have now discovered to PD I explained to them the knot or lump on both sides of my penis. I recently had a vasectomy and decided to ask my Urologist about the condition on my follow up visit. I explained that (More recently)at the head of of my Penis I have a slight indention equal on both sides(not curve) just a decrease in girth during erection. My Urologist suggested I take Vitamin E but now after reading this site I wonder since its been 10 months have I waited to long?

It's still worth a try. MG

 

June 2007

about 6 months ago I noticed that when I get an erection, the penis bends severly to the left about half way down and is quite painful. I find no evidence of any scaring anywhere on the penis. I do not masturbate. Prognosis?

If the bend is severe, the chance this will go away on its own is lesss than 30%. MG

what holds the most promise in your estimation? I have suffered with this condition for three or four years, with a huge loss in volume and a near 90 degree bend...surgery has always seemed a bad option to me, painful and impractical and awkward with my career requirements, and I have tried several alternative therapies, with no or very limited success. My wife is very understanding, but this has affected my psyche in ways that are not always evident, even to me. What about transdermal electomotive administration of verapamil and dexamethasone? Do you know about the process and is it worth investigating?

Electromotive treatment is not anymore effective than any of the existing medical therapies. With a 90 degree bend and 4 years duration, I would not expect you to respond very well to any of them. MG

At present my Doctor has me on 40 mg of Lipitor per day. My question is, can Neprinol be taken along with Lipitor?

I know of no contraindication, but would recommend you check with your pharmacist. MG

If a mechanical stretching decice was used in conjunction with a vaccum pumping device and an agent that helped to block the formation of scar tissue, would it help reduce the affects of an already present PD condition? It seems a stretching device could help stretch the scar tissue and improve elasticity slightly (though what damage to the tissues has already been done), and the pumping device could help draw blood in and around the scars. Obviously whatever agent is used to prevent further damage would have work pretty well. Also, after the FDA is done with their trials, how does one become a candidate of the Collagenase trials set to begin soon?

Mechanical stretching may prove to have a role in the treatment of PD, particularly in conjunction with collagenase. At present, trials are planned for early '08. When I have more details I will announce them on this site. MG

I was diagnosed with Peyronies about 5 years ago. Do you think there would be any benefit to my starting Vitamin E medication at this point?

Yes, it may help to stabilize the condition. It has been used for many years in the treatment of PD, despite the lack of effectiveness when compared to placebo. MG

I am a 60 year old male who recently completed 3 years of treatment for bladder stones and, ultimately, BPH, for which I underwent the TURP procedure. This resulted in the utilization of catheters four times in the 3 year period. Following the TURP in 4/06, developed Peyronie's condition within several months. Was prescribed Colchicine and Probenecid but was discontinued after a month due to digestive side effects and lack of improvement. Is there any research on use of nattokinase and serrapeptase on this condition (sold as Neprinol)?

Multiple urethral instrumentation has been associated with PD. There is no good research on either of those two products. MG

I am 29 years old and the first signs of PD appeared 6-10 months ago. I've been seeing an urologist after I found a hard raisin-sized lumps on both sides of my penis. I have no significant curvature (but slightly curving to the left). He said it was peyronies plaque, and started treatment with injections of verapamil directly in to the plaque. I did this 5 times and then he said we should wait to see what happens. During the treatment the lumps grew to be more a big lumps "in the middle" of the base. After the treatment it got slightly smaller and less painful, but now its growing again. Tha plaque is now approx 1by 2cm (?) and goes the base of the penis and in to my body. It sometimes appears to be like a ring, not unlike someting you would have on the wine-bottle.The treatment ended in april-may. I'm going back to the doctor by the end of june. Lately I have experienced that the base of penis has a significantly smaller diameter than the rest of the erection. This makes the base of the erection soft and flexible, and this is a problem... It is not very painful to have an erection but it is not pleasant either. The "non-erected" part is about 2 cm long, The rest erects ok, but not as hard as before. Is there any chance to reverse this defect without surgery? Is E-vitamins the best medicine, or should I ask for any prescription-drug? What are my prognoses for getting back my "old penis"?

If you haven't been on colchicine 0.6 mg three times a day, it would be worth a try. You will probably recover your full function, though there may be some permanent physical changes in the penis. MG

I have been diagnosed with PD. Since this is not a very common situation in men, I did not think that I would find anyone in are who would be able to treat it, I was correct. I have been sent to a Urologist in Boston who, after our appointment, agreed to help treat me with a series of injections - I believe he said that they were Vargas injections. Not sure if I have the right name as so much went by me at once His intention is to contain the pain from a 120+ degree angle until the curve stabilizes. After which, I assume that surgery would take place. Is this the accepted method in todays treatment of PD?

That would have been verapamil injections. The approach is correct, some kind of medical therapy to get to a stable point, then the option of surgery if the deformity at that time precludes normal sexual activity. MG

1. Urea: Have their been any studies on the use of either urea injections into the pelile plaques or topical urea via DMSO delivery? The biochemistry books say urea can denature & soften collagen. Urea has been used commonly for some skin conditions & for some rare eye problems. 2. Heat: The biochemistry books state that mild heat ( no specific temp is mentioned) or alkaline solutions will convert collagen to elastin. Are these possible therapy options (or research options) that could be used on penile plaques to soften them without killing the normal tissue cells in the penis? Possible heating modalities are heating pads, baths, radiofrequency, or ultrasound. It is hard to find references on what are the safe temperature & pH limits for penile tissue.

Ultrasound has been used, though not as a heat source. I believe that urea can only be used topically - I don't know to what extent it will penetrate the skin. MG

A short description of my case: I (49) always had a straight penis. Three years ago I had pretty rough sex (from behind). I did not feel any pain or hear a "knack" however. When I masturbated the next day I realized that I had an appx. 40% curve to the upper left. I went to an urologist two days later who said he could have done something would I have come the day it happened. - I tried Vitamine E for two months, but stopped when it got negative press in the papers (possible side effects on the heart). - My condition has not changed since then. Still curved to the upper left, no pain, can get an erection. It is not as good as before though. - My question: is there still a chance for improvement by taking medicine? Do you recommend surgery? Wait for FDA to approve new medicine?

After 3 years, this is unlikely to improve on its own. With a curve of only 40 degrees, a nesbit procedure would be an option if the deformity really intereferes with sex. If not, it may be wise to await the approval of new medications. MG

I am 63 years old. I had a bend in my penis starting about 12 to 14 years ago. It was about 45 degrees. The pain passed after awhile. I read about PD and seen that it might corrected itself after awhile. I did nothing. To the best of my memory, the curve never got better. But I began to lose my erection. It slowly went away to nothing. I have not had intercourse in at least five or six years. I have checked and there is no erection at night. The size of the penis has shrunk steadily. To the point now that there is almost nothing there except skin. I do not have blocked arteries according to my cardiologist.

See a urologist about the impotence problem. You may be a candidate for implant surgery. MG

 

May 2007

My husband was diagnosed with Peyronies about 4 years ago at the age of 26. This came on suddenly with a strong bend and a lump under the skin of his penis. His curve during erections is curved into his stomach, he has lost rigidity but has never had any pain. His penis has narrowed greatly and is thinning more. I know this is bothersome to him. I read on the site that this is usually present in older men and I'm wondering if Peyronies starts at this younger age is there a possiblity that it will be worse when older, or is this disease very slow and stable. He saw a doctor 4 years ago that just looked at him, no testing was done and he said it appeared to be Peyronies, he has never seen a urologist. Do you think a Urologist is necessary? My final question does Peyronies ever reverse or get better? He has never done any treatment and it causes me no discomfort.

It would not be a bad idea for him to be checked by a urologist. Fortunately, the chances of spontaneous improvement are better for men in his age group than for older patients. MG

You’ve commented several times on the trials soon to be done on Collagenase for treatment of PD. Can you update the status of trials, availability of that med, dosage recommendation, and its trade name if it is now available?

Clinical trials of this drug (to be conducted by Auxilium Inc.) may be starting late this summer. Currently it is an investigational drug and is unavailable outside of FDA sanctioned clinical trials. MG

I am a 68-year old, very athletic (tennis, cycling, weightlifting, treadmill, etc.). About 4 years ago, I detected a notch at the base of my penis on the left side and experienced a slight pull to the left with a full erection. It was not painful and did not interfere with intercourse. As time went on, over the course of six months or so, the pull to the left became more severe, but my penis remained straight. Then it started to curve and twist in a counterclock-wise direction during erection. It was then that I started researching PD. I had been a regular consumer of Vitamin E, so I tried applying Vitamin E liquid (from the capsule) directly to my penis. I did not see any noticeable change over a three month period, so I discontinued it. I waited another year as I watched my penis become more misshapen to the point where it is currently (bent at 90 degrees to the left from the base and flush against my body. In a relaxed state, it is very shrunken and twists about 45 degrees to the left making it very difficult to urinate standing because I never know which direction the stream will go until the flow starts. I am still able to sustain an erection and able to twist my penis 90 degrees to the right to make it curve upward without any pain, but intercourse with my wife is impossible. I have seen two urologists with photographs to show my condition. Both have suggested the Nesbitt procedure, but I hesitate to make the decision for surgery. I am currently on a Coumadin regime for AFib due to an artificial aortic valve. From the pictures of PD I've seen, I've never seen such a severe curvature. Do you think I may have torn an attaching ligament at the base of my penis or possibly have a blocked artery from all my cycling activity? Thanks for your response.

This degree of deformity does occur in Peyronies disease - I think that is what you have. Cycling - induceded arterial injury would create great difficulty obtaining a firm erection, so I do not think that is the case. MG

My 18-year old son had surgery four weeks ago. His penis is bent to the right about 45 degrees but only with an erection. After surgery, the bend is about the same but now it looks almost like a sharper corner where the incision was made on the left side. While at the hospital, the doctor told me they artificially aroused him and it was straight then. He is very upset that this will all turn out to be a chronic condition and can't be fixed. He's very frustrated.

I assume that based on his age, your son's surgery was for correction of congenital curvature. Usually the penis should be fairly straight soon after surgery. If it is not, and does not improve, I would suggest he be evaluated by a surgeon who specializes in reconstructive surgery. MG

Hi, I'm 19 years old. Ever since I can remember my penis has been bent in a downward motion. There is a semi-dark ring around my penis and when flacid, it indents all around my penis at that spot causing an hour glass shape.. The bent is a dramatic fall right at the middle of the penis about 45 degrees, maybe more. I feel no pain, I've never had sex. What should I do? What does this sound like?

Sounds like congenital curvature. If this presents problems when you become sexually active, seek the opinion of a urologic surgeon with this type of experience. MG

I was diagnosed with PD about 18 months ago and was offered surgery last month after having been on Vitamin E for a year, Nattokinase and Serrapeptase for the last 4 months with no effect (Based on photographs pre and post consultation). At my pre-op discussion the surgeon proposed the Nesbitt procedure but after debate he agreed that in my case the significant narrowing at the base caused by the plaque would remain and I was convinced that any benefit from straightening would negligible in allowing me penentrative sex, due to the collapsing of the penis at the narrow point regardless of a full erection and the mental issues. My surgeon said that the only other option was a 'Lee' Procedure which would remove the plaque and replace with other tissue, but it would take 3-4hrs. I have been unable to find anything out about any Lee procedure.

I think he means the Lue procedure, developed by Dr. Tom Lue at University of California San Francisco. He is correct that based on the narrowed segment, some type of graft surgery would be required. MG

You recommend verapamil or colchicine. Are there reasons for preferring one or the other? I have a few discrete nodules, but the bulk of the problem seems (to me) to be more diffuse fibrous tissue that started just behind the glans and has been growing steadily back along both sides for five months now, causing shortening and some curvature. Hardness of the tissue (or maybe it's surrounding inflammation?) waxes and wanes daily. I've been taking Potaba for a couple of weeks, and Vitamin E for several months. My condition is worsening rapidly, and I'd like to seek additional treatment as soon as possible. Of verapamil and colchicine, is one better for my version of PD? Can they be combined, with each other and/or with Potaba?

Yes they can be combined. For diffuse scarring (opposed to well-localized disease) oral therapy such as colchicine would probably be better than local injection with verapamil. MG

Thank you for this site. I have classic PD. In 50's, married 25 years. My wife only has sex on the top and I am fairly sure that my PD is from coital trauma. Can continuing to have this sort of sex with my wife make my PD worse?

If the PD has been present for > 18 months, it would not be expected to worsen. MG

Have you heard of a link between Peyronie’s and HPV or any other STDs?

I have seen cases following severe herpes outbreak, but know of no published confirmatory reports. MG

Can Peyronie's disease be caused by the use of a penis pump? Also if I already had a mild case of Peyronie's disease, what type of effect could using such a device have on me? I ask because recently I made the mistake of using a pump for the first & last time, since then I have had some pain & discomfort.

Vacuum pumps have been used to treat PD, as a form of physical therapy or stretching, with mixed results. If left on for too long they may cause discomfort, but would not be expected to cause PD. MG

I have on the underside of the penis on the left and on the right side near the corpus spongiosum two relativley hard plaques, which are about 2 cm long and maybe 3 mm thick. They start just below the glans of the penis and go parallel straigt down the penis. At the beginning i have had pain when i have had an errection. Now the pain is gone. My penis is not bend. I visited two urologists and both say it is IPP. What do you think?

These do sound to me like IPP (Induratio Penis Plastica, another name for PD). If you have neither bending nor pain I would suggest staying on vitamin E with expectation of eventual resolution. MG

I am interested in treatment others with this condition have tried and their degree of success or lack of success.

I will publish the reports I receive from patients. MG

I have have this condition for nearly 4 years. I have tried vitamin e since the onset and still take one 400 i.u. per day. I took Potaba for couple of years to no avail. I had the collagene injections (3) and they did not work. I am into my 3rd month of verapamil 15% at cost of $750/3 month supply. I have not seen any improvement for anything. It may even be worse. My doctor suggested I obtain an erection and manually try to bend the penis back with expectation of breaking up the scar tissue. I began taking alprazolam 1mg/3 times per day for anxiety. Shortly after taking that medication, I noticed the onset of peyronies. It hurt to have an erection for first time or two but does not hurt any longer. I have about a 45 degree upward curviture and inhibits my sexual performance physicaly and mentally. I am 59 years old and very healthy. What is your recomendation? Is the manual bending causing more damage or is there a chance it will help?

After 4 years I doubt the manual bending will help. MG

I have about a 2 shortening and a lateral right bend, that is progressing even while taking vitamins, and medicine. At what degree of lateral bending will intercourse become difficult? Can the size of ones partner contribute to peyronies and make sex more difficult?

More than 45 degrees usually produces difficulty, especially with a small partner. MG

I am 54. After reading all I could find on this, i have concluded this is the issue I have with about an 80% bend up plus 30% to the left, I have an appointment with a qualified urologist, in 3 weeks should I take any pictures and take them along? I have had this for about 4 months my GP said it was no big deal and nothing could be done anyway, glad I found some hope even though it is not much.

Yes, pictures will help. MG

I've seen ads about Neprinol. Is it a good alternative to treat PD?

There is no peer-reviewed data on its results. MG

My husband started using Viagra on occasion over the last 8 months. About 6 months ago, he developed Peyronies @ about 90 degrees. Could the Viagra been a cause of this?

Studies on phosphodiesterase inhibitors (Viagra, Levitra, Cialis) have show they may have (theoretical) benefits to patients with PD. I doubt the medication was the cause - quite possibly your husband's original erectile dysfunction was due to early PD, which became more apparent when the erections were improved with medication. MG

I have had PD for almost a year, 62 years old. two visits to Urolugist, with wait & see. They have advised a vaccuum devise, using 30 minutes a day, to increase blood flow to plaque, and try to straighten curvature of almost 90 degrees. have only used several days, and have noticed some improvement. Is this new.

The physical stretching provided by a vacuum pump may be of benefit - studies on the effects of mechanical stretching or traction are underway currently. MG

I'm 17 and have had a significant congenital curvature for as long as I can remember. It is roughly 25-35 downwards and occurs over a 1-1.5 inch area. I've noticed a couple of small-ish indentations on the bottom of the corpus spongiosum (within this 1-1.5 inch area) when it is really hard or when I physicaly hold my penis straight. I'm not sure whether or not its PD, as there is no pain or bleeding and I've had it for a long time, but the indentations have gotten me suspicious. I'm planning on taking Vitamin E soon. Would you recommend vit. e or something else? And if it is PD, I'm looking at alternatives to the nesbit treatment like injections, etc.

The only effective treatment for significant congenital curvature is surgery. MG

My partner is 44 years old. in the past year, i have noticed a change in his erection / penis appearance / sexual performance. he is continually swearing that he is "shrinking". he also seems to have a bit of a curvature that seems to be gradually getting worse. although these issues seem key... the thing that bothers me is his rigidity and position while erect. as most men seem to become "horizontal" when erect and standing-up, his penis continues to hang straight-down (vertical) despite his erection. he has also seemed to loose rigidity. he seems to feel this is bothing his sexual performance. it just seems weird that he is 'erect', but is soft at the base of the shaft, causing him to hang down.

This well could be PD, have him see a urologist. MG

 

April 2007

I am a 52 yr old male, married, whose wife refused to have sex anymore about two years ago. I masturbate on average once a week and have had no unusual events. About 2-3 weeks ago I noticed an upward curve starting from behind the head of my penis. I'd say it is slight at 15 degrees. I take a daily dose of naprosyn 500mg for headaches/arthritis as needed and a daily protonix 40mg for acid reflux. Can not having regular vaginal sex contribute to this problem? Can I continue to masterbate with no ill effects?

I don't think lack of vaginal sex caused this, unless masturbation has been exceedingly rough. If it isn't, I would not expect any ill effects. MG

I 've had peyronies for two years now ..the pain has gone away and severity of the curve isn't as bad as it was but since but since I was diagnosed with PD I've noticed that my ejaculations are much weaker and smaller .Does PD affect how much one ejaculates ?

No, it does not. MG

I am 41 years old, and about 4 years ago (following an episode of straining caused by constipation), I noticed a slight left curvature of my penis when flaccid (it is not too severe when erect) and a slightly raised band near the base of the shaft (on the right side) measuring approx. 5mm wide by 2cm long. It is not usually too painful, however erections sometimes are slightly uncomfortable and there are times when I cough or sneeze that I can feel a sharp pain in this area. Recently, erections have become weaker, which prompted me to see a urologist. He said there was a 90% chance that it was not peyronies.

I would agree. MG

I'm 52 years old...I began noticing curvature, and pain, during erection approximately 6 months ago. I also noticed the feeling of plaque along the shaft, when not erect. I began doing research and realized I may have Pyronies. I finally saw my Urologist last month and he confirmed I did have it. He told me that all the injections, medications, and other alternative treatments - discussed on the Web - didn't work and is just a waist of time. He told me to give it 6 months and make another appointment if things don't get better. He also stated that the only corrective procedure to fix the problem, if it doesn't reverse itself, is implant surgery, and that should be avoided as much as possible. The problem I'm having with this response is, I've read - on the WEB, that if you treat the problem early enough, some of the proposed remedies may work. Yet, if you wait too long, it'll be irreversible. At what point should I become concerned that my condition is irreversible? It's only been 6 months since the onset of this condition, and, I'm still experiencing pain during erection, I have approximately a 90 degree upward curvature, and it's virtually impossible to have any kind of sexual relationship with my wife. In an attempt to minimize this posting, I too share the same questions as your other contributors to this forum relating to the cause of my condition, (i.e., four major surgeries requiring a catheter in a short period of time, prolonged use of multiple medications to treat inflammation, nerve damage, high blood pressure and cholesterol readings, etc.), so, what can you tell me that would suggest that my condition may correct itself by taking this wait and see attitude, or, should I seek another medical opinion due to the current state of my condition? In addition, is there any update you can provide on the clinical study involving the scar dissolving enzyme Collagenase?

Medical therapy offers optimal chances of improvment when given early - within 6 months of onset. So even if results are not great, it is usually worth a try. The fact that you have 90 degrees of bend at 6 months makes it unlikely the condition will reverse itself. Collagenase clinical trials are expected to begin late this summer - I will post notices on this site. MG

I've had Peyronie's disease for several years now and I'm fairly certain it was caused by "grinding" that strippers do when giving you a lap dance. Sometimes they "grind" so hard that my penis would be bleeding when I got home. I used to have an fairly large attractive penis, but now have a much shorter double curved one (to the left and down). At my urologist's suggestion, I started taking 400mg Vitamin E daily to no effect after two months or so. He then recommended that I up that to 1600 mg daily, still to no effect after two months. I'm 59, 6', 200 lbs. have difficult to treat high blood pressure, high cholesterol (which Lipitor seems to be a miracle drug for), and an enlarged prostate for which I take 1800 mg saw palmetto daily, again at my urologist's suggestion. Otherwise, I'm in very good health and rarely get sick. Is there something else I can do to correct the curvature & loss of size?

After several years, your condition would not be expected to resolve on its own, or respond to medicines. Surgery can straighten the bends but cannot restore lost length. MG

i have peyronie's for as far as i can remember, im 30 yo now, and i just got married , my wife never complained about it, and i dont feel any pain at all, however, the curvature is 45 to 50 degrees, the curvature is downward, and the plaque is at the base of the penis and it is like ring around the penis, my erection is always incomplete that i always feel that my penis can get harder and bigger than the actual size which is 6 inches, from what i know there is no cure except surgery, but there is a fear of lenght loss and erection

If this goes back as far as your can remember, you either have congenital curvature or memory loss. Seriously, this is probably not PD. Your best chance would be to see a urologist with experience in this type of reconstructive surgery. MG

My son,19 years old and has a 38 degree downward congenital curvature and is considering the Nesbit Procedure. He is very concerned about the loss of length and his condition has caused him a lot of stress. He has avoided sexually activity because he fears the curvature would be painful for his eager girlfriend. Do you think a 38 degree downward congenital curvature should be corrected? What degree of congenital curvature should be corrected? How much length will he loose? Would his downward curvature cause discomfort for a sexual partner?

Downward bends cause problems when they exceed 30 -35 degrees. I would anticipate some degree of discomfort in his partner. Expected length loss with a Nesbit would be approximately 2 cm. He would be a good candidate for surgery as in experienced hands his problem would likely be corrected. MG

I have recently been diagnosed with PD. The Doctor suggested vitamin E (which I will take!), but I found another possible option in Neprinol. Has there been any success using this?

There is no placebo controlled, peer-reviewed data on results with neprinol. MG

Could Peyronie's Disease be caused by HIV infection?

Not to my knowlege. MG

I am a 64 year old man. My penis bends to the left about 25-30 degrees. I have PD and I had the surgery in 1997 which corrected PD only slightly of which I could have intercourse you to about 2 years ago when the curvature has returned. I have no problem getting an erection, but the erection is weak, and before I can insert my penis, I lose the erection. I believe the lost of the erection in mental, and I believe that by getting the surgery again to straighten my penis will give me the mental confidence that I can perform. I would like to get the surgery again, but I am concerned because the last surgery was not successful, do you think that having the surgery again to straighten my penis would give me the confidence I need to maintain an erection? Is there a list of board certified urologists?

Chances of successful re-do surgery would depend of exactly which technique was used intially. Earlier in the forum you will find referral information on qualified physicians. MG

I have had two very small bumps on the underside of my penis, dead centre width-wise, about 3-5cm from glans length-wise, for several years... the bigger one measuring about 6mm in length, the smaller one only about 2mm. Unfortunately I can't remember when I noticed them - maybe I always had them? I can't recall them changing at all. They are easy to feel all around, and can be moved about a little - though I assume they would have to be connected somehow, they almost feel "loose" like they are floating around just under the skin; i.e. they don't really feel attached to the "thick" tubes deep inside the shaft. No pain whatsoever, no history of injury (unless you count circumcision at age 5). I have not noticed any change in curvature and I have a fairly straight erection, maybe a slight downward bend overall but nothing signifcant. So what could these little hard bumps be?

Perhaps sebaceous cysts. This doesn't sound like PD. MG

 

March 2007

Has anyone ever had any benefit using serrpeptase to correct their peyronies curvature? I have been taking a serrapeptase supplement for 2 months now and have not seen any improvement. I believe my peyronies was brought on by taking the antibiotic Cipro. Soon after finishing my Rx of cipro, peyronies developed....30 degrees to the left. I was straight as an arrow before. I am 51 yrs old. This has been hell for my sex life. I am not happy.

I am not familiar with serrapeptase. I know of no relationship between PD and the use of cipro. MG

I have suffered with this all my life. Please send me more info as soon as possible.

Lifelong difficulty means you have congenital curvature, which is surgically correctable. MG

I was circumcised when I was 44 years old. I had discomfort from the scar of that procedure for many years afterwards during intercourse. I questioned the urologist on whether or not the circumcision could be the cause of the PD.

Circumcision has not been shown to cause PD. MG

My husband has been on very high doses (600mg) of Diflazole (Fluconazole) for 10 months to treat Valley Fever. For the 3 1/2 months he has experienced symptoms of PD, including slight curvature and pronounced pain during erection. Has a connection ever been made between PD and Fluconazole? Or Valley Fever and PD?

This is an interesting question - to my knowlege, and based on a bit of research I've done, there appears to be no relationship between PD and either Valley Fever or Fluconazole. MG

I had some rough sex last weekend and the next day I noticed that while limp my penis seemed to look puffy. At the base of my penis a tendon or vessel feels hard and hurts a little when applying pressure to it. Did I sprain my penis during sex?

Yes that sounds like the case. You will probably get better in about a week. It takes a pretty serious injury or "cracking" during intercourse to cause PD. MG

my husband was just diagnosed with PD today and was given a script for potaba.in most cases does it work?and how quickly?

FDA has designated this drug as "possibly effective". It should be taken for at least 6 months, though in my experience the chance it will cause significant reversal of bending is around 30%. MG

I'm 48 years old and about a year ago I went to a urologist informing me I had Peyronies. Initially I started with a curve to the right. There was scar tissue easily palpable in the upper third of my penis. After one year it seems to have changed considerably. Now, I have palpable scar tissue in the upper third, center of my penis. The plaque feels considerably large and I'm erect the "full" all except the top one third of my penis. My head does not engorge as it once did normally but there are times when it does engorge normally but from the base of the glans down about 1/3, it's narrow. I hope this is clear enough to be understandable but I was wondering if this plaque or scar tissue is treatable.

Yes, this is treatable but after a year the response to a variety of medications is less than it would be initially. MG

I am a married 62 yrs old and have noticed that during erection my penis is bent probably 70 degrees to the right at the base and the penis itself is gently curved to the left as well. There are no symptoms at any other time. First noticed both phenomena 3 or 4, maybe 5 mos ago. It has gotten worse as time goes on. I am capable of regular sexual activity, but my wife is also my age, so it is generally not an issue, unfortunately. No known trauma. No other known physical abnormalities, except sciatica over the last 1 1/2 years or so and other back muscle problems aggravated by golf and right leg is 1/4" short. For a couple of months around the time this started getting progressively worse, I do remember a nagging pulling/dull aching sensation in right groin area radiating up toward the hip, which I dismissed as something done during physical activity, and I did not link the two. At time of erection I can bend the penis from the base to the straight position without pain although there is a tightening sensation on the right side of penis and in right groin area, although a pulling pain in the right groin area is produced when going further to the left, increasing in direct proportion to how much further I move it to the left. I cannot move it more than 20 to 25 degees to the left during erection due to pain.

Eventually the pain felt during erection and bending will resolve, though the scar may become more dense in the future and make straightening the penis (as you described) more difficult. MG

I am 33 years old, and about 4 months ago I noticed a small bump in my penis. One day when I was urinating with my penis bent down, my urethra hurt, and blood came out. Urination afterwards presented no blood, but some pain. I left it as so for about a month, then I got a prostate infection. I saw the doctor and he feels I tore my urethra, and put me on antibiotics for 3 months. He said that the urethra will heal itself. The prostate infection is gone, but I still get an irritation when I urinate, somtimes worse then others, and sometimes no pain at all, and it feels like there is something inside my urethra afterwards. I went back to the doctor, and he gave me alpha blockers, and it seemed to help with the penis pain, and even my urethra felt better. Once in awhile I get the sensation that there is something inside, but my doctor says it's inflamation. I am on my last month of antibiotics, and my doctor wants to send me to a urologist if this persists. My urine test came back negative for blood, and no infection. What would the lump had been. It seems to be gone after the initial painful urination

It is not clear that this is PD. I agree you should see a urologist. MG

About a month ago, I engaged i allowed myself to engage in a prolonged erection(about5-7 hours). I did not physically stimulate myself during the encounter and it was mental and the erection was straight through, it was on and off during the whole time.Afterwards the left side of my shaft became very swollen for about one week and the veins seem to have some thrombosis.A week later the swelling went down and it still felt somewhat swollen but was not painful anymore, i have been able to get erections and for the most part they seem normal.Most of the discomfort happen when im flaccid.When soft I notice an area on the left side of the shaft that kind of looks like its protruding and it goes in a line kind of down about quater of an inch down the side.Its tender,I cannot find this bump when im erect.What could this be?

This does not sound like PD. MG

I saw my Family Doctor last week because I was having pain in my penis (Burning and Stinging). He ran a number of tests for Urethritis,Chlamydia and Gonorrhea. All Came back Fine, this was last Thursday, But on Saturday i was having very painful Testicles and it felt like i was sitting on a tennis ball along with the urge to urinate every 30 minutes. This is when i noticed that i had slight Curve in my penis to the left 5-10 degrees. I went back in to see him Yesterday to make along story short seems like i got prostatitis. I told him about my sudden curvature in my penis and showed him a picture of it fully erected. He didn't seem concern or didn't think it was PD. I'm 28 years old, Healthy kid, I have always had a downward erection, but this new curve still has me worried. Should i be concerned?

No, I suggest you take the reccomended treatment course for prostatitis, give it another 6 or 8 weeks, then re-evaluate. It does not sound like PD to me. MG

 

February 2007

Hello, two weeks ago I had surgery to correct a congenital downward curve. The surgeon used the modified Nesbitt procedure. He told me that the most he would shorten it would be no more than 1/2 inch. He also lengthened my penis by releasing the suspensory ligament. The combined procedure has left me over 1 inch shorter erect. I am supposed to begin using the penile stretching device in a couple of weeks. However, I'm not confident that I will gain much with the device. My question is can the Nesbitt procedure be reversed? Can the plication sutures be removed and the penis unplicated or unfolded in order to restore my original length?

This would not be easy to do, depending on the method used for plication. MG

About three months ago I began to experience pain during intercourse. I then noticed that my penis was bent down. I am 58 years old and have always had a very straight penis. Eventually the worst of the pain subsided, but it still not altogether comfortable to have sex. I had been taking Atenolol which I did not tolerate well. It zapped my energy, made me disoriented, and left me very weak. I finally convinced my doctor to prescribe a different med. I am now on Enalapril. From what I have read in your forum, it appears the Atnolol is associated with PD. Could Enalapril have caused this or is it contributing to my still bent penis.

Enalapril is not a beta blocker like atenolol, and it has not been linked to PD. MG

as long as I can remember my penis bent 15-30 degree to the left ( dont know exact angle as differcult to measure), I experience no pain and feel no lumps or bumps, so am curious as to why it has a curve?

Some degree of congenital curvature is common - this will cause you no difficulty. MG

I'm 33 y/o and I was diagnosed PD 3 years ago..I'm doing fine.... no curvature, fortunately, but sometimes I have a slight unlocated pain.... Wondering if Vitmaine E would help... just to keep it down and if yes, what type would be the best ( there are so many) And where can I buy POTABA?

Vitamin E seems to stabilize the condition, so it has been used in the treatment of PD for many years. Placebo - controlled tests have not proven its effectiveness. Potaba requires a prescription. MG

you indicated that you would be starting some new treatment trials at the end of 2006. Did the trials have positive results, and if so is the treatment now available? I

The clinical trials with collagenase (Auxilium A4500) have been delayed due to manufacturing issues. Hopefully we will begins trials this summer. MG

Last December I wrote, and I have attached the text for identification below. I thank you for your guidance and supporting this web site. At this time all signs of Peyronie's have disappeared. I immediately stopped taking the glucosamine and chondroitin supplements, began taking vitamin E, and added units of bromelain. I also indulged in a few hot baths, gentle massage, and topical application of vitamin E (although I am told this is almost completely useless). It was pretty tense there for a while, as erections became increasingly uncomfortable and lumpy nodules began to form along the middle of the thickened tissue. Then, just as quickly as it seemed to be advancing, it turned around and went away. Whew! I hope this may be of help and encouragement to others. Again, thanks for your help and support.

(previous message:)

I have been taking glucosamine and chondroitin to help with knee problems. I'm 48 years old, and recently noticed the painless development of PD. Is it possible that these supplements have assisted in the progress of PD? I believe this may have started when I was hit in the penis while playing tennis over a year ago, but as I said, I have not noticed any symptoms until the last two weeks. Also, my doctor has recommended topical application of verapamil which is relatively expensive and not covered by my insurance. Is there any benefit to immediatly using verapamil, or would I be just as well off to use a vitamin E treatment (800 mg. daily), and then use the verapamil cream as a last resort?

Thank you for taking the time to send this followup - it really helps all of us. MG

I have been diagnosed with a mild case of peyronies. There is a scar near the middle of my penis. There is no curvature, but sometimes on the way up, my penis has trouble getting erect only in the middle section of the shaft. I noticed that sometimes, the tip of my penis has a hard time getting erect also. I have to flex my muscle to push blood to the tip, but it often deflates. Can a scar in the middle of my penis be causing problems for the head to get erect? Even though it is about 1 1/2 inches away from the scar. Usually when I use a condom during sex, the head feels like it is getting squeezed and smaller because of the condom. Is the condom too tight, should I leave more room, or is it the peyronies? Is it unhealthy to have intercourse when the tip of the penis is not fully erect?

Physically, diameter restriction at mid-shaft can reduce filling of the distal penis (near the head). This is a result of the PD rather than the condom. Sex in this condition is not harmful. MG

I'm 21 years old, I have read your site and found it very educational about PD, since a year ago I noticed a small very small lump on the right side and almost the base of the penis. Talked to my dad who is a Dr. and he said well if it doesn't bother you, you'll be fine, well i was fine, but 4 months ago I started to have some pain during erection not bending, and also noticed the lump might be 2 lumps instead of one, talked to my Dad again, took me to an urologist and I said to him about PD, he said no it is not PD, then a month later i couldn't have an erection without awful pain and some curvature to the right then went to the urologist once again who took some ecography of the corporea cavernosa and found a small i don't really know if it's a scar or plaque of about 2 mm. And told me i had PD. Then prescribed Butazolidin for a month to see if there's any progress he didn't recommend surgery and in fact said something that scared me, I asked about the surgery procedure and he said: "No, what for? i might ruin or screw you up, then you wouldn't have a good erection". That was quite scary to hear and in fact i might look for another urologist since that told me he doesn't know how to treat PD. I'm starting to take vitamin E then Butazolidin. My question is how should I treat PD, and if the treatment is no good, is there any good place you would recommend for surgery, and the risks of having Sexual Disfuction after the surgery?

It takes PD many months to respond to medicines - you need to stay with the vitamin E and consider colchicine or verapamil. In the (unlikely) event that your condition does not significantly improve over 12 - 18 months, there are effective surgical remedies. The urologist is correct in advising you that surgery would be inappropriated at this point. MG

I'm 48 and have developed a hard ring completely around my penis. A very tight indention. I do not have a problem with a curvature. Just the tight indention located below the head. Could this be a form of Peyronie's Disease?

Yes. MG

I am 36 and for the past year my penis has been bending to the left and now bends to around 60 degrees. Over the past month it has started twisting to the left as well. There is no pain associated with this. Should I seek any medical advice or treatment?

Yes it would be wise to see a urologist. MG

January 2007

I've been told that applying heat (45 degrees C) can help halt the progression of Peyries. Is there any truth in this? Thanks for the support you're providing us with in a seemingly unsolvable condition.

I know of no data to support this. MG

I'm a 29 year old man and I believe I probably have Peyronie's disease. Three or four years ago my penis began to curve, it is about an inch shorter when erect than it used to be, and I have an indentation on one side. However, other symptoms don't seem to match, including that the curve still exists when flaccid (I really have to aim when urinating which I did not used to have to do). The curve has not gotten worse in several years and so appears stable. For religious reasons, being unmarried, I have never engaged in sexual intercourse but I am concerned about my ability to have sex after marriage. I don't have any basis to know if I'll have a problem. My curvature is to the right, and depending on how you measure it, it is anywhere from 12 degrees (from the center of the base of the penis), to 30 degrees (from where the curve begins, about halfway up), to 40 degrees (from the middle of the curvature). My questions are: Does this sound like Peyronie's disease to you, what is the correct way to measure the angle of the curve, and based on my description do you think I would have any difficulties with sexual intercourse?

This does sound like Peyronies disease, although not severe. By tracing the erection against a piece of cardboard, you can use a protractor to estimate the amount of bending. I do not think you will have any difficulty with intercourse. MG

Can discontinuity in cavernosal artery lead to impotence or Peyronies disease? I am asking this since my ultrasound result showed that there has been a discontinuity in left cavernosal artery. Penis bends there very easily (I have a left side bent of about 25 degress) and the left part of my penis is weaker than the right one. I have a difficulty in maintaining erections. I am afraid that repeated bending on the left side can worsen by bend

Your ultrasound finding has no demonstrated link to Peyronies disease. MG

I understand that some research is going on and some breakthrough is expected in near future (Hope so). But I thought that may be the male hormonal therapy would help cure peyronies. As I understand, little is known about this disease, is there a possibility that peyronies is simply a hormonal disorder and symptoms like penis distortion / loss of length etc are direct results of that disorder only? Since I am suffering from this mysterious disease, I currently have little sexual urge or libido compared to my previous state, and I know for sure that loss of libido is real and not psychologial in nature. It has suddenly subsided, may be ten percent of what it used to be. Is there any way that taking some male hormones will restore it?

There is no evidence that PD is a hormonal disorder, or that taking hormones will help it. MG

2 months ago I started to feel a lump in penis when flaccid with no bending when erected. Urologist said it could be the start of PD and recommended Vit E. At a similar time I also started to have a swollen neck lymph which separately was analyzed with a negative result saying it is nothing malicious just inflamed. Question is : can PD cause the swell of a lymph in the neck ?

No. MG

I'm 28 years old having developed what appears to be Peyronie's disease a little over 2 years ago. I haven't had any pain associated with erections though the curvature to the left seems to be very slowly getting worse (I would say it is about 30 to 45 degrees now). I don't see/feel any sort of scarring or lumps, though it appears that there is a slight indentation on the left side where the bend occurs. Oddly enough this started out of the blue about the same time as my Eczema. I believe I developed an allergy to fruit which seems to trigger the itchy skin which won't go away unless treated. Is it possible that my condition is a result of an auto-immune disorder which is for some reason causing scarring/reduced elasticity below the surface of the skin?

I am not aware of a connection between exzema and PD. MG

Is there any chance that acupuncture could help with PD?? Also what is the status of collagenase, is it available now, if not when do you believe it will be? I broke my hip after a fall in 2004 and had a catheter inserted while in the hospital. It was in for about 8 days. Was not able to have sexual relations for over 8 months because of severity of injury. After rehabilitation is when I first had any symtoms of PD I believe it may have been caused by catheter.

There are no studies showing benefit from acupuncture. Collagenase clinical trials will probably start in the summer of 2007. MG

I am 21 years old and my penis has twisted to the right and up for as long as I can recall. This is not congenital; the shaft is straight until about halfway up, where the raphe deviates even when flaccid. There's a definite palpable plaque at this point. It's obvious to me that it's being forced to curve across the plaque. This has worried me my whole life and I'm worried that sex won't be enjoyable like this. Would you recommend a nesbit procedure? Would I lose any sensation?

The decision for surgery depends on the severity of the bend, and the functional difficulty it is causing. If you were to elect surgery, the Nesbit would probably be the best. The liklihood of it causing sensory losss is < 2%. MG

Three weeks ago (after intense and painful sex with my girlfriend) I noticed that a scar have appeared on the downside of my penis, near the head. The scar runs parallel to my penis, and has 1 centimeter long (0.39 in) and 3 millimeters width (0.12 in), and is right underneath the skin. I feel like an inflammatory process in taking place where the nodules are. And it's painful, specially when I have an erection. I did not experience any bend in my penis yet. But I am really scared because this condition has started only 3 weeks ago, and I don't know how it is going to evolve. Do you think I can develop a pretty serious case of PD?

This does not sound like PD, though it would be wise to see a urologist. MG

I am 39 years old and happily married. About three years ago I noticed a small, pea sized lump in the shaft of my penis. The lump felt to be fairly centrally located i.e. in the core of the shaft, rather than some of the other presentations reported as being around the shaft. Slightly concerned, I went to visit my doctor. He reassured me that there was nothing to worry about as I wasn't in significant pain and had no bend in my penis. However, about 3 or 4 months ago, I started to suffer from significant discomfort during intercourse and in the last few weeks have developed an upward curvature. At the moment the curvature is probably only 10 -20 degrees, but I am concerned that it will get worse. Do you feel that the problem is likely to become significantly worse.

Considering that this originally started 3 years ago, further progression seems unlikely. MG

I have been taking 400 I.U. of vitamin E, along with 400 MG of pentoxifline 3 times a day for almost a year with no change in the hourglass shape of my penis (diagnosed as Peyronie's Disease) with the exception that the penis seems to have decreased in length by almost an inch. Why the shortening and should I just give up and live with it?

Yes, that would be a good idea - unfortunately, length lost to PD usually does not come back. MG

I've read that vitamin E has been used as a Peyronie's treatment for decades but I haven't been able to find a suggested dose, other than one mentioned by another gentleman on another board. He'd been taking 1,200 mgs. a day for 6 weeks with no notice of change. Is there a recommended dosage? Also, I've recently read of acetyl-L- carnitine being taken orally for Peyronie's (along with a laundry list of other ailments, including dementia). Any thoughts on the advisability of using acetyl-L-carnitine?

Vitamin E is taken as a single 400 unit capsule once daily. One preliminary study with acetyl carnetine showed it was no better than placebo. MG

I noticed a small, hard, whitish bump at the underside of my penis, pretty much right above the scrotal sac. Shortly after, it seemed to have developed into a sore. The sore and bump are gone, but now I have a tightness at the base of my penis my I achieve an erection. It seems to pull my penis downward and is painful and sex is difficult. I am 42 years old and considered obese with an unusually small penis. My penis does "turtle" in to the existing fat pad above my penis, and it seems that my erections are not completely full. The area above the tight "band" is not as rigid as before and the underside seems flat.

This sounds like PD, so I would reccommend you see a urologist. MG

I am 61 and have just had an ultrasound and been diagnosed with pyronnies. Could you tell me if this could be the cause of the loss of a small amount of urine dribbling after urinating.

No relation. MG

Since i can remember i have had a 40-45 degree left curve to my penis and while erected it bends downward because of this left curve. I have had no pain during erections. I am currently taking 400 iu of vitamin E hoping this will fix this to some extent. However im am unsure if this is PD or a congentative curve. I dont feel any noticable bumps it just is hard on the left side of my penis. I can see a slight curve when not erect. Will this degree of bend make it impossible to have intercouse? Also what do you think in your opinion this is?

This is congenital curvature, and it will not prevent sucessful intercourse. MG

I first noticed the bending, but I gave up on that after 6 months or so. I have done nothing about it since that time. Also, when I was in highschool, I used to measure my erection at about 7", but now it is only about 6-1/4". This condition has been stable for a couple of years now. The shape and look of my penis are admittingly causing me a great deal of psychological distress, which I am trying to get past. My girlfriend says that it is minor and it makes no difference, but I fear she is just trying to spare my feelings.

Thanks for sharing your insight. MG

I am 34 years old and have a penis that is curved identical to a banana when erect. It points downward, and is approximately 8.5" in length. It is very uncomfortable to the other partner during sex. what can be done?

This sounds like congenital curvature. As the deformity is causing discomfort, you should consider a Nesbit procedure. MG

About a year ago my I noticed my penis seemed a bit shorter when erect, and a few months later I noticed it bending a bit to the right (maybe 20 degrees) when fully erect. At the point of bending - on the side of the shaft on the right side, about a 1/3 of the way up from the pelvic bone - was a very small hardened area that I can feel only when erect. I never had a painful lump there at all; it just appeared. I still have no reduced elasticity when flaccid. I also have no pain when erect. I saw a urologist who, from my description, said it was PD, but never used an injection to see it erect and could not detect the hardened area when it was flaccid. For the past 9 months I have been topically applying Vit E and DMSO, and internally taking MSM, Quercetin, and Vit E. No changes have occurred, but I"m naturally worried that it could get worse, and, having always had a straight penis, would like the straightness back as well as the length. Is this PD, what else could I be doing, and will something this relatively mild likely resolve on its own?

As the bend is only 20 degrees and there is not pain, there is good chance this will not progress. MG

December 2006

It is with intrest I have read your public forum since I have Pyronies. It is my suspicion that I aquired Pyronies from a Kidney Stone Procedure were a Catheter Procedure was used . I am in Canada and have seen Three Uroligist and all agree that this procedure is not the cause. I have read many other Blogs and forums and in them both Doctors and Insurance Companies claim that PD is not caused by (correction) it is an impossibilty that a Catheter caused Pryronies. It is mind relieving to find an honest answer in your forum I thank you and stress that you inform your Colleges World Wide that a Catheter Procedure can and does cause PD. If you could take the time to explain how a Catheter can cause Pyronies on your forum I along with many others would greatly appreciate this and would pass it on to Medical Professionals in hopes that a proper risk assesment can be presented to Patients.

Urethral instrumentation can precipitate PD, by transmitting an inflammatory process from the urethra to the tunica albuginea. MG

I have been over masturbating since the age of 13. I am 40 years old now and for as long as I can remember I had proper erections only 2 times in my life. My penis gets half erections usually and have curve to the left quite a bit. I am unable to achieve proper erections and I ejaculate too quickly. For the last 8 mnths, I feel something like a painful tear on the underside of my penis near the head. I feel severe pain in my penis for about 6 to 8 hours after ejaculation. My penis is not hard enough when erect.

I would reccomend you see a urologist with a special interest in sexual dysfunction. MG

I would like to know if the Nesbit procedure is covered by United Health Care, I believe to have seen your name in the provider book, however I don't know if this procedure is cover by it.

You will have to check with your insurer or you doctor. The CPT code is 54360. MG

I'm 58 years old; ever since I was 18 on my first sexual experience the girl I was with, kind of made fun of me about the 'crookedness' of my penis. After a while I realized that I was born with a different penis. I continued with some active relationships until I got married at 22. I did not suspect to have a real problem with my penis, till my wife began to complain of discomfort on her perinea area, in certain positions, the bending downwards caused discomfort to her many times. I only had some slight pain in the top of the curvature mostly when she was on top, making the pain worse at time of ejaculation. We had 3 children and except for those of some times painful episodes 'masked' by the excitement of the moment, we had a 'normal' sexual life. In 1978 (30 years old) I had a corrective operation that changed my penis from looking bent and downwards to not so bent, more horizontal, yet still pointing down. My size was reduced about 1 inch in the operation, however my widht is above average according to my wife's experience as an RN during her hospital working times. Nowadays it takes some adroitness an more time to climax for both of us. I feel uncomfortable not being able to 'connect' with her in the appropriate very sensitive areas, clitoris, unless there is manual stimulation on her, at the beginning, middle and end of the intercourse. I kind of got used to it, yet I still wish to be able to climax without much of manual stimuli. Many times my penis 'pops out' of her vagina spoiling the whole act. Also she still feels discomfort in many positions on her perinea. I wish to have erections with at least straight penis, not a one pointing downwards, is there any possible solutions for this?

A second plication procedure would deal with the downward bend, though it would cause additional length loss. MG

A few months ago (in early September), I had some pain in my right hand, with symptoms similar to a fibromatosis. The pain disappeared after I stopped working out. In October, two lumps appeared spontaneously on the top of the shaft (close to the base of the penis). These lumps are not painful but feel hard when touched (just like cysts). I don't have painful erections or any curvature, but I am worried. Do you think that could be PD?

If these are like cysts in the skin, it doesn't sound like PD. You might benefit from seeing a urologist. MG

Im 56 and recently experianced discomfort from night time erections there is a lump on the topside of the shaft and its started to bend in an upward direction its there is only slight discomfort when erect. my ? is a few years ago I had n.s.u. that caused extremly painful ejackulations could this be the cause of my problem. im going for an altrasoud check next week but having read most of the threads i feel a litle more at ease after all I was thinking cancer

I think the checkup is a good idea, though it doesn't sound like cancer. MG

I'm 20 and my penis has always erected upwards to around 10-25 degrees depending on the hardness. I've had this ever since i can remember, memories as early as 9 or 10. I didn't start masturbating until i was 15. However i had noticed the curve prior to this when i was desperate to urinate. Can you tell me if some penises naturally curve upwards like the old greek statues you see.

Yes, and if the bend is bothersome, you should consult a urologist. MG

i have been having sex with my girlfriend for about 3 months now. At first I couldn't make her climax, but we found a position (with her on top) that would allow her to. She sits slightly forward and it allows my penis to touch her g spot. However, I feel like my penis may be bending slightly, there is some discomfort at times. Should I be worried about damaging my penis?

If the bending causes discomfort, beware. Peyronies - causing injuries during sex occur most frequently with the woman on top. MG

Two yrs ago I had the prostate removed by anterior resection with no difficulty. Unrelated a few months later I had to have urethral resection. I then developed PD (I also have constrictions in the hands) and had surgical correction for the downward curve that made intercourse impossible. I injected trimix for ED. I then slowly began to develop an upward curvature. It is now fairly significant. My partner is being satisfied and thus I am pleased. I however am now anorgasmic. It used to help to trap my testicles between my thighs but it no longer does. I have the feeling that there is something useful it that last piece of information but do not know how to take it further. Any suggestions re: this issue of anorgasm.

This is a difficult problem - I'll put it out to our readership. MG

I've had PD for several years - I'm guessing six to eight. Is there a way to determine exactly how long the condition has been present?

No. MG

My boyfriend, the last 3 or 4 months, has less rigid erections and there is an hourglass appearance to his penis when it is erect. He fell asleep one night with a condom on which was pretty tight around the area that curves in on his penis. Do you think this could be Peyronies or the condom could have had anything to do with it?

It may be an effect of the condom, which I would expect to resolve within a few weeks. MG

I am a 23 year old male who had surgery about 8 months ago to correct a 60-65 degree downward congenital curvature. The operation was performed by Dr. Lue at UCSF using a plication technique (similar to a Nesbit). Before the surgery Dr. Lue and his staff told me this surgery had excellent results and had done many similar on young patients with congenital curvature. The operation was very successful in that I only have a remaining curvature of about 5 degrees (which is almost unnoticeable) and lost very minimal length (going from a hair over 6 inches when my penis was forced straight, to 5 3/4 inches post op). There was also no loss of feeling. Overall, I was very satisfied with the result and am glad I decided to do it. The only slightly bad aspect of the operation was a pronounced circumcision like scar, and a penis that is more sensitive to being used. For the first couple months it was moderately painful to masturbate (especially ejaculating) and would also hurt for several hours afterwards. Now, 8 months later, there is no pain what so ever, except if I do it more than once a day, which is very uncomfortable. My question is, will my penis likely continue to become less sensitive at this point, or will it likely always be painful to use it more than once a day?

I think the hypersensitivity problem will resolve with time. MG

I'm a 59 year old male post prostate surgery 2 years ago. Prior to surgery no problem with Pyronies. Since the prostate surgery I've had problems with erection and the only thing that really help was tri mix injection. probably about 6 months ago I started to develop a curvature to the left, about 30 degrees now. What are your thoughts on the effectiveness of verapamil topical gel by pd labs.

The experience of my patients with this agent have been unimpressive. MG

I am 70 years old and developed PD about 1-1.5 years ago. My local urologist (3rd world country) recommended cochicine as he related PD with gout (which I do not have). Nevertheless, I note in the Pill Handbook that colchicine is not recommended for seniors and that it has a debilitating effect. Since I am physically active and wish to remain so, can you confirm these side effects and comment on how significant the downside is

Colchicine when taken 2 or 3 times daily over a couple of months seems to be well tolerated. The major downside is diarrhea, which occurs in a small minority. MG

I'm 49 and saw a Urologist about discomfort in erection. He diagnosed Peyronies and said that I have no bend because my plaque is bilateral. I've been reading on this forum about the problem and learn that many men lose length, width and overall size to their erections. My question is this: exactly how many does this happen to, and how many don't experience this long term diminishment?

Most men with PD and no bend do well, without progressive deterioration. MG

I just turn 55 a week before Christmas. September 2006 I started to feel a pulling during erection and noticed my penis was bending to the left. It continues to worsen. I saw my urologist in November. He told me the situation could get worse for up to a year, but may subside before that. He informed me that men who have Peyronie's, usually have problems with their tendons. And I do. My tendon problems started when my family physician put me on Lipitor for 3 to 4 months back in 2000. I stopped for a few months and the tendon situation lingered, but didn't get worse. Then he prescribed Zocor. I stopped taking Zocor in two months when my tendonitis was becoming more inflamed. My family has a history of producing high cholesterol, but I was more concerned with the tendon inflammation and pain. I was informed of Red Yeast Rice being a natural statin, so I started taking it in November 2005 to lower my cholesterol. It worked, but in August 2006 I noticed my tendons becoming more inflamed again. Then in September Peyronie's started. I wonder if there could be a connection? Did anyone else develop Peyronie's after taking statins for high cholesterol?

Interesting, I'll submit this to the readership. MG

I have been taking glucosamine and chondroitin to help with knee problems. I'm 48 years old, and recently noticed the painless development of PD. Is it possible that these supplements have assisted in the progress of PD? I believe this may have started when I was hit in the penis while playing tennis over a year ago, but as I said, I have not noticed any symptoms until the last two weeks. Also, my doctor has recommended topical application of verapamil which is relatively expensive and not covered by my insurance. Is there any benefit to immediatly using verapamil, or would I be just as well off to use a vitamin E treatment (800 mg. daily), and then use the verapamil cream as a last resort?

I have seen anecdotal reports correlating the use of these supplements with PD, but there is no population based data available. Based on the results reported with each, you probably would be as well served by starting off on vitamin E only. MG

November 2006

I’m 36 and have had PD for 10 months. My bend is mild around 5-10 degrees to the left at the glans. The pain was severe at first but has mostly gone away after months of Potaba. I still get mild pain when I put pressure on the plaque and after intercourse. Is this normal? Also what are the chances it will become worse at this point such as a 90 degree bend? I notice the plaque keeps changing size and is sometimes hard to detect.

At this point you are very unlikely to progress to severe bending. Some discomfort in this area with physical stress is normal, though it should eventually resolve. MG

A 6 wks ago I began noticing that my boyfriend was having a difficult time with erections. While in the foreplay mode it would be "hard" but when we began to have intercourse it would lose some of its hardness. He just attributed it to being overly tired with his working hours, etc. A couple of weeks later I noticed the curve (about 45d) this time and then the painful intercourse showed up. After researching and finding this website I asked him about injury in previous intercourse, neither one of us remember an incident like that. I then have felt his penis, erect and soft, and am not able to feel any type of lump or scarring. I did read about Vitamin E (especially with the tocopherols) and he began that about a month ago. At what point would an improvement start showing? And I also read that it can just disappear as fast as what it showed up ( which did seem like overnight, within a matter 2-3 weeks), what are the chances for that to happen? What should we be looking for before he needs to start seeing a specialist for this?

This is a typical story for PD. If he doesn't see any improvement with vitamin E after a month or two, a visit to a urologist would be worthwhile - most drug therapies for PD work best in its early phase. MG

I am 16 years old and recently discovered a slight "indentation" on the right side of my penis near the top. I noticed it a day after I had masturbated pretty intensely. It really has no effect on me when I am erect; it only has an effect when it is flacid or semi-flacid. In the flacid (usually more often in the semi-flacid) state I have lost a little length and girth, but it is mainly like a "dent"...it gets narrower at one point then goes back to normal girth at the head and points slightly to the right. After reading up about peyronies, I thought it could be that, but then I saw that it usually happens in men much older than me. It doesnt happen to me all the time...only about half of the time. The other half of the time it is normal. I am just afraid that it is peyronies because it looks really weird when it has the dent and I really don't have anyone to talk to (I live with my mom and grandmother, and I'm pretty sure they don't have any advice on this subject!!) Do you think this could be peyronies?

No. MG

I am 34 years old and I contracted genital warts at the age of 20. I had recieved treatment (freezing) off and on until the age of 30. On my very last treatment my doctor blasted me with the nitrogen gun on a wart located on the top left side of my penis unlike any doctor has done prior. About a week later a small bump formed underneath the skin where the doctor blasted me and I started to develop slight curvature. I went to another doctor and recieved an ultrasound and it came up negative. A couple months passed and I had another knot form underneath my skin on top-left underside of my penis which I can feel when I'm both erect and flacid. I received no treatment for my std in this area however. Consequently, my curvature worsened, and I have slight curvature (deviating left) even when I am flacid. Does this sound like Peyronies?

The persistant or worsening curvature and formation of palpable bumps does sound like PD. It might be reasonable to see a urologist. MG

I am 16 years old and I have peyronies. From what I have gathered, generally older men get it, is that true? Well I have had it all of my life from when I can remember, can you give me any advice as to what I should do?

You have congenital curvature, not PD. If it is severe, you could consult a urologist regarding a Nesbit procedure. MG

I was diagnosed with PD 13 years ago. I had one consultation and didn't go back. The pain eased some months later and I've had a healthy sex life since. I'm now 41 years old and some months ago experienced some pain again and then, to my horror, some loss in length. After overcoming the mental stress this caused, my wife and I still enjoy a healthy sex life. Is it though discussing this with my doctor and is there any treatment I shoud pursue to either a) restore length, or b) reduce the risk of further deterioration?

Fortunately it sounds like your level of function is good. There is no known remedy for length lost due to PD. Perhaps vitamin E supplement would be adviseable for prevention. MG

The claims of shortening are dramatic is some cases; Some shortening is understandable from the curvature aspect, but is there a cellular or structural change occurring, a shortening of a tendon, or something else to cause that degree of shortening of the penis.

Shortening is due to overall loss of elasticity in the tunica albuginea. MG

Well over a year ago I mentioned that I thought I had Peyronies Disease to my doctor and he just blew it off saying not to worry.....I mentioned to him a few things I feel as he should have zeroed in on but he didn't and since then I have had a real problem dealing with this. One of the things I mentioned to the doctor was that about 3 or so years ago while I was urinating I started peeing blood.....not just a redish color, heavy red, like pure blood.....The doctor said I had probably either ruptured a vessle or was passing a stone......not to worry !! Not too long afterwards is when I noticed a problem with curvature, then with rigidity, then with maintaining any form of rigidity.....As time has passed over these last few years, there has been no more blood which I am grateful for, but my erections have become to where I don't even call them erections anymore. It may be due to the mental state I'm in with this or my prostrate gland (which he said was enlarged)...I have no idea what the cause is, but this is bothering me because I'm 66 years old and still in real good health and I still have the urges but not the capability to pursue these urges, and thank god I have a wife who is working with me even tho this has to be frustrating for her also. So to sum this up, what I have is a bent or crooked penis that no longer gets fully erect to what it used to be and does not hold what erection it does achieve and did at one time spurt blood that the doctor was not worried about. It would seem to me that anytime you have blood is something to be concerned about !!!!

I would be concerned about that as well. Perhaps you should get another opinion. MG

 

October 2006

I am a 29 year old with PD. I smoke pot, with no explicit connection at all to the PD. I've heard of people connecting it, saying that they get "numbness" in the penis or a "tingling" feeling or "rigidity", but I do not experience anything of the sort. I am only trying to do whatever I can to heal this problem as I am now to a stage where I can feel pain at times, both erect and flacid, and the bending has begun (so far 10 degrees to the left). My doctor put me on Potaba, vit E, and I'm looking into enzymes and antioxidants (noni, pineapple, Neprinal, xango). I smoke pot, but these days I am limiting it to a vaporizer which cuts the smoke intake by 80-90%...the "bud" is still green when I'm through with it...but I still get the THC into my system. I feel like the pot helps me stay positive, but I wonder if it could hinder the healing or even add to the PD problem.

I have no data regarding the effects of Marijuana (THC) on PD. MG

In May ,I had surgery for a torn cavernosa.Five months later after most of the swelling has gone,I have a hardening scar tissue developing where the tear was. I've since went back to my urologist and he prescribe oral vitamin E and see him in 6 months.Currently I'am still having sex and only have a slight right curve and a little less ridged.My question is simply...is there something else I can do to stop any progression of possible Peyronies type scarring

Simply staying with the vitamin E is enough at present - the post operative scarring (which is expected) may take many months to "loosen up".

I have had peyronie's symptoms for close to 18 years. I am a 37 yr. old male. I have increased curvature, but the biggest problems are loss of size (girth) and some function. I can easily see the scarring on the shaft. Has the enzyme approach shown any recent promise? A very standard answer from doctors is to "leave it alone". I find this increasingly unacceptable.

I agree that ignoring a bothersome condition is not very satisfactory. Unfortunately, neither medication nor surgery is effective in restoring length / girth lost to PD. MG

i noticed lumps in each of my feet one just below the ball of foot and another a few inches more toward heel-- a podiatrist said it was like scar tissue--but he called it normal-- was that a pre indicator of PD?

Plantar fibromatosis (Lederhose) causes lumps in the sole of the feet, and is related to Peyronies disease. Perhaps vitamin E supplementation, or colchicine 0.6 mg three times a day for 3 months will help to prevent PD in this setting. MG

I was just diagnosed with this disease. My question is this. Does contninued sexual activity help or hinder healing from the disease? If I do not engage in sexual activity like masturbation, can this worsen the disease? Does moderate masturbation help keep tissues more elastic? Will it help reduce the curve?

Continued sexual activity will not worsen the disease, as long as you avoid activities that cause significant pain. MG

I am now 51, divorced and developed PD 3 1/2 years ago. When having sex with this very active girl - she moved one way and ouch! Didn't think much of it but noticed a thinning at the base days later accompanied with pain while engaged in intercourse. This worsened over time to include indentations, downward curvature, reduction in filling up the bottom portion and some length issues. Now the pain is increasing. I have had a coarse of injections which were not fun and they gave me limited results so I stopped. Now I have to do something, what is the question. I never did the Vitamin E protocol but I will. Interestingly enough I have been recently diagnosed with Gout and I read in your forum that there is a link - what is the link?

In a survey of men with PD, gout was present more often in the men with PD than in the control (normal) group. MG

I mentioned in my earlier mail that somebody had recommended to massage penis with olive oil for length and girth, well, I have been doing that for past three months and the result is quite amazing. I had lost one-third of the length and I believe I have recovered more than fifty percent of that. I regularly take vitamin E 400 i.u. that as per my observation improved the curvature bud didn't help restore the lost length. This is what I do each morning before taking a bath. I massage penis with olive oil, like you massage your arm, for about 10 minutes, and then wash after 10 minutes. There is no side effect. Of course, experts can debate but that is what I have actually tried. I'll continue this for another three months and will update the forum members.

Thank you, we'll look forward to your followup. MG

I am a 41 year old male who approximately 5 months ago discovered a small pea sized lump in the shaft of my penis seemed center dorsal. I attended my GP and she inspected it and said it could be just a mass, PD but I was not erect at any time during the examination. Upon discovering the mass I immediately began thinking worst case scenario cancer with a penectomy, scary thing finding a lump. The lump seemed malleableand was not painful when flaccid. When getting an erection it felt tight and a bit uncomfortable more uncomfortable with erection. The mass now appears to be harder in texture to me and today I discovered a slight upward bend to my penis below the glans. Going to be taking 400 UI Vitamin E immediately hope this helps. My question is in regards to the curve does it progress more when being sexually active or masturbating? And can I expect it the bend to worsen if more calcification occurs, I have the intense fear of seeing it worsen some candy cane shaped thing. As I stated the bend is very minor but I felt a slight difference today dread losing length as I am not big but average in the length department. From all the reading I have done it sounds like PD to me.

I would agree. Being sexually active should not contribute to worsening. MG

I was diagnosed with Peyronie's 3 years ago, at the age of 26. I developed a 2nd plaque two years later, and a 3rd plaque a few months ago. Also in the past few months, I have developed bilateral plantar fibromatosis. Given my age, otherwise excellent health, and no family history, I am at a loss as to why I have such a predisposition to these fibrotic disorders. Are these conditions likely to continue to progress throughout my life? Is there a doctor with a more general knowledge of fibrotic disorders that I should consutlt (as opposed to Urologist for Peyronie's, Podiatrist for plantar fibromatosis, and hand specialist when I eventually develop Dupuytren's)?

As yours is a genetic condition, it is likely to continue. A Rheumatologist knowlegable in connective tissue disorders may be able to help you. MG

I'm 59 yr's old. Over the past 4-5 months the distal aspect of my penis has started bending up. It is now at a 45 degree angle. There is no pain. It sounds very much like PD to me except for the fact that I absolutely don't feel any nodules or plaques in either the flaccid or erect state. Can one have PD without a palpable plaque?

Yes. MG

3 months ago i sustained an injury to my penis. I felt pain for a day and then noticed that my penis when trying to get erect made an upside down u shape. I noticed on the underside of my penis that there was a purple line going across it. Needless to say, the urologist checked it out, he said there isnt any scarring, but it might be peyronies. Ever since then, my penis curves, sometimes it doesnt fully extend...Other times it would get hard and more rigid...it's been 3 months and i have been taking vitamin e...That purple line on the underside of my penis is still there and hasn't gone. Sometimes it looks like its fading, and other times it doesnt. I think this is peyronies, but how severe do you think it is?

It sounds like you sustained a tear of the (bottom) of the corpus cavernosum, with the resulting scar producing this PD-like effect. I doubt that after 3 month it will get any worse. MG

Within the past year I have been taking Atenolol and have started having symptoms consistent with PD. I'm approaching the age of 71. As to severity, imagine a clock face with 9:15 being normal. I am at 7 minutes past 9. I have read (on the internet) that PD has been associated with Atenolol, but when I contacted my pharmacy supplier, they could not confirm this. My question was, "if PD is caused by Atenolol, is it reversible with a change in medication?" Can you address this question for me?

There is a known association between Peyronies disease and the use of beta blockers (including atenolol). While these drugs have not been proven to cause PD, there is reason to expect improvement when they are discontinued. MG

I was diagnosed with PD in July—I got to an urologist about two months after I noticed a severe curvature of my penis (curving toward my stomach upon an erection). I have no pain. I was prescribed aminobenzoate potassium, 2 grams taken twice, four times daily. I mix it with V8 juice. I also take potaba, 500 mg, 8 tablets, 4 times daily. Finally, I rub a small amount of verapamil (15%) with rimso-50 twice daily. I hate taking all these meds. Is there anything else I could do differently? My Doc did not mention vitamin E, but it sounds like it could help. Also, are there any contraindications/side effects or other things that could happen to me if I do or do not take all these meds. I am married and am 56 years young.

The only common side effect with the regimen you are taking would be stomach or intestinal upset. MG

A patient has Peyronie's disease (abnormal curvature of the penis) for 4 years. It all started when he began university and had an unusual (not sexual) interaction with a woman, he remained fully clothed and may have had physical trauma to the erect penis at this time. He is 22 years old, slightly overweight, a student with a sedentary lifestyle. He also displays intermittent red itchy rash in the groin region and has had a yeast infection in the past. His bowels are soft, his tongue has a thick greasy coating, and it effects him emotionally. He is a light sleeper, pensive, gets colds quite frequently, and describes his digestion as 'sensitive' presenting with gas and bloating. Science now says that all cases show a certain plaque & inflammation on the musculature of penis. Peyronie's in my opinion may be displaying with autoimmune characteristics (unknown inflammatory response), … My first thought is a clear bland diet (to minimize yeast-immune reactions). VITAMIN E: this anti-oxidant has other uses in the treatment of scars, and has been employed in the treatment of Peyronie's disease since 1945. Is there anything else anyone can recommend?

Please keep us posted on his progress. MG

I am 53 and have had peyronies for 3 years. I tried all the different medicines listed on the web site. I am getting an implant, the one that pumps up the cyclinders with fluid. My question is: What is the average recovery time from the implant? I know everybody's body is different but just wanting to know when I can return to work.

There is a fair amount of discomfort following implant surgery for PD. The average time to return to work is about 10 days. MG

 

September 2006

do you have any experiences concerning the so called " Jet Cutting " operation method ? Is this operation-method with " water " a good alternative to established surgery?

I do not have personal experience with this technique, which employs high pressure water to dissect the plaque. I would be wary of any method that does not use a well-established and reliable method for reconstructing the defect that remains when the plaque has been removed or divided. MG

Any studies yet on collagenase? Is there any other medications coming down the pyke?

The latest information I have suggests clinical trials with collagenase are now expected to begin in the summer of 2007. MG

docotor, i noticed a slight bend in my penis(when erect) towards the left about 9 months ago and started reading up on different conditions. i drew the conclusion that it was PD coz there was a small lump half way to the middle of my penis and towards the left. After drawing my conclusion, first i got depressed and then i forced myself to be Ok with it. I am 35 years and at the present moment single so i am not suffering from the emotional trauma that most of the writers here suffer from. There was no pain associated with the bend and i used Vitamin E for a few months and then discontinued coz there was no change. The lump is still there but for the first time today after 9 months i had a painful erection during masterbation and the curve was more noticeble (i think). There is no shortening of my penis but there is an hourglass kind of figure on the left side of my penis and a bend. Is my disease getting worse? Does it normally happen after 9 months? I was hoping against hope that i will be one of the few lucky cases in which the disease will reverse but now i am slightly worried. Any chance of it still going away after today's episode? Oh and one more thing .....i was prescribed to use inderal (beta blocker) which i discontinued after a month. Could this medication have cause my PD coz i don't remember having an accidental damage during intercourse

Yes there is a chance it will go away. Beta blockers have been associated with Peyronies disease, though a true causal relationship has not been proven. MG

You often say that it's important for men with PD to remain sexually active. Is there a physical reason for this, or is it purely psychological? I'm 39 years old, the onset of PD closely followed the breakdown of a ten-year relationship two years ago. Not only have I not sought any medical advice I have also chosen not to pursue further relationships, due to the embarrassment caused by my size and deformity. What harm do you believe I'm risking to myself?

Long periods of sexual inactivity can heighten psychological barriers to establishing new relationships, as well as physically impair erectile function. MG

my erect penis has always curved downward. A section in the middle seems more narrow then the rest of my penis when flacid. I have never had any complants from any girls and I kinda don't even care that this is the way I am. But it does bother me. Do you think this condition could turn women away from me because of thier normal perseption of the male antonomy?

If the bend is less than 30 degrees or so, I doubt you'll have any complaints from your partner(s). MG

I have been diagnosed with a mild case of peyronies. I have no curvature but once in a while the center of my penis takes longer to become erect. I also take karate lessons and play sports on a regular basis. I am very cautious and I wear a cup every time which still allows some shock to come through if hit hard. If I were to suffer a blow with a cup on could pressure worsen my scarring. Also, cups can sometimes be tight and uncomfortable. Could the scarring become worse from sitting in tight boxer briefs or jock strap for a long period of time.

I don't think you are at risk; really only the erect penis is vulnerable to the injuries that are associated with Peyronies disease. MG

I have a lump inside my left corpus cavernosa. Erections are painful in the beginning but not once erection is achieved. BTW, I am a diabetic, 49 years old and recently started penile injections for help in my sexual life, but stopped taking them after four or five injections. I distinctly remember as taking only two injections on the left side where the lump is located. I can feel the lump which is about half an inch lengthwise. Should I see a doctor?

Yes. The lump is probably related to the injections. MG

I have had peyronies now for some time (45 deg upward bend) and just had my second visit to the Consultant here in the West Midlands (UK). As opposed to surgery he has suggested I have 3 sessions of Shock wave treatment which he claims has a High success rate which is the opposite to your opinion. Why would he tell me the success rate is high when you quite clearly you suggest the treatment is ineffective.

I cannot explain why your doctor disagrees with published data. Shock waves are great for brittle calcifications (stones), but have no effect on scar tissue (Peyronies plaques). This treatment may help the pain to go away, but that will happen in the absence of therapy. It will not straighten your penis. MG

I have a natural curve to my penis, about 45 to 50 degrees to the left. I was wondering if there is a natural or minimully evasive way to straighten it. From self examination, if I pull it straight out when flacid, I notice that the taut tendon or ligament is on the left side of my penis, not in the center. Is this an abnormality, and if so, is this what's limiting the left side to expand, causing the tissue on the right side to expand around to the left? I've read some websites promoting penis stretching devices and they cite its historical success in primitive cultures and that it can be effective for straightening out curvatures as well (or would it simply increase the length without removing the curve). I've also read that the Nesbit procedure is fairly safe, simple, and effective but that it limits the legth to the shortest side of the curve. Could I do both; stretching first and then the Nesbit? I'm not looking for enlargement, just to straighten it while maintaining the length of the longest side if possible. Even if I could get a partial correction, 22 degrees would be better and functional than 45 degrees.

The taut ligament you are feeling is actually the left corpus, which is congenitally shorter than the right side in your condtion. I see nothing wrong in trying the stretching device, as long as you don't use excessive (painful) force. If this doesn't work, the Nesbit procedure would be indicated. MG

Dr. I am 65 years old. I have had Ledderhose for the last 20 years, about 10 years later was told I had Dupuytren contractor, then five years later found two lumps in my penis Urologist told me it was Peyronie's Desease. It has been five years I have no curve but have lost about 3 inches in lenght is there anything beside vit. E to combat these problems?

Unfortunately, with the concomittant presence of dupuytrens and lederhose, there is little liklihood you will respond to medical therapy. MG

I'm 52 yrs old. I've always had a slight congenital curvature to the left. About a little more than a year ago i noticed it to be a bit more curved. And about 10 mos ago, it seems to have curved a bit more and has a slight ...very slight...indention on the left were it tends to bend, which is about an inch. from the base. I was totally unaware of a disease called Peyronies or any such condition. I just went to see a Urologist today. I told him that I had done a lot of reading on the subject, and what i cannot understan is why i have no "Lump" that i hear about where it would bend...and i do not have any pain. None whatsoever, However, it is somewhat uncomfortabel during sex only because of the curve/bend, which is about 20...maybe 25 degress from center. He suggested a wait and see profile. However, he only examined me visually, and did not enduce an erection or x-ray it or anything. should he have?

There is usually no lump or pain in cases of congenital curvature. Based on the lack of functional impairment, I would agree with the wait-and-see. An X-ray is not necessary at this point. MG

I have been taking Timolol GFS 0.5% one drop in each eye daily for Glaucoma for about 4 years. I believe within that time frame is when I first started to notice a slight right curve in my penis during erection. In the last 6 months the curve has increased to about 45 degrees. I never made a connection between my eye medication and PD until I started to research on the Internet as to what this condition could be. When I read that beta-blockers could be a cause for PD I looked more closely at the brochure that comes with the medication. Under HYPERSENSITIVITY UROGENITAL it lists Peyronie's disease. Are you aware of others who have PD caused by Glaucoma medication?

While there is a known relationship between Peyronies disease and beta blockers, I do not know of any patients who have developed PD from the use of glaucoma meds. MG

I did a stupid thing. I cleaned my penis with a toothbrush because there was so much "white dirt (dead skin or something)". It worked and i was not really violent. I used it on the glans, in the junction and below the glans. A month later i got pain in my penis and later on curvature. so.... Can bruise or damage on the penis surface or skin cause PD-conditions?

Yes this is possible. MG

I see you mentioned that "if a medication called collagenase is approved, mechanical traction may have an important role to play in assisting the enymatic action of this drug." would this also work for people with congenital curvature?

Good question. Collagenase would not be indicated for congenital curvature. Traction alone might help but there is no data available. MG

I was looking at the sypmtoms of PD. They were Pain with erection, Bending and or indentation of the erection, Loss of penile length, One or more hardened areas, or plaques within the wall of the erection chamber. Well out of these I just have one symtom i.e. the bending of the penis and it is not a slight bend. Its more than 45 degrees. Do I have PD And tell me if the absence of the hardended tssues in the penis is possible in a patient with PD.

Yes this sounds like PD, which can occur in the absence of any easily detected hard areas. MG

I AM INTERESTED IN CONNECTING WITH SOMEONE WHO HAS GOTTEN SOME FORM OF SUCCESSFULL TREATMENT FOR PEYRONIES DISEASE MY NAME IS KEITH, I HAVE HAD IT FOR ABOUT A YEAR. I DON'T HAVE A CLUE ABOUT IT. I DON'T KNOW WHAT TO BELIEVE.

I will post any responses. MG

 

August 2006

I have a back operation in sept /06 and abouth 12 weeks after the surgery i noticed when i get an erection that i had allot of pain i ignor it then as time went by just like overnight i got a 45 degree upward bend making it imposible to have sex and the head dosn't fill dose this sound like PD i started to take vit E 400. the pain has since disipared almost fully but the bend is still there i need to know if you think this is PD

Yes. MG

We have the techology to put a man on the Moon, create a liveable Spacestation, and cure some forms of prostate cancer with Cryogenics, but cannot find a cure to the most devastating disease to men since the Bubonic Plague. Welcome to the 21th century! I guess since it is not politically important enough, no federal money is allocated for research for this dreaded male disease. I have had Peyronie's for 10 years, married 5 times, and I dread every day of my life. I am a sexagenarion heterosexual male seriously thinking about becoming a transexual female.

Whoa! MG

My penis curves up and to the left, which makes having intercourse difficult, if not impossible. I have only had the symptoms for about three months. I have read that using a vacuum pump sometimes helps to straighten the penis. I also read that using a penis lengthener device sometimes helps to straighten out the penis as well as making it longer. I don’t care about making it longer, but it would be nice to have it straight again. Any thoughts on these remedies?

Using some type of mechanical traction will probably not hurt, as long as the force applied is not excessive or painful. There is no good data on the results with these devices. In the future, if a medication called collagenase is approved, mechanical traction may have an important role to play in assisting the enymatic action of this drug. MG

about an inch up from the scrotum it is about the size of a pea, this bump has no pain when touched but does not seem to be getting smaller, it has been their for about a month and im worried because i have been applyin bacitracin ointment on it and it does not seem to be going away. their is no discharge and i am not sexually active, i want to know what steps i can take to help it shrink and go away. and possibly a timeline for how long it will be their.

Not every bump on the penis is PD. MG

I have a question about traction devices. I read that they are also used to help correct a mild penis curve as well as increase length? Is this true, and if used correctly, are these products safe?

Please see the entry above. MG

A couple of years ago while masturbating, I felt something like a painful tear on the underside of my penis near the head. A few months later, while ejaculating, it felt like my urethra also tore a bit (or something) and the hole became a little bigger. I don't know if these two injuries caused it, but sometime after them, the sensation in the head of my penis as well as the shaft became dulled. At times, touching the head can even be slightly painful. In addition, I need to frequently urinate and comes out less strongly than before. There has been little bruise/scar on the underside of my penis just below the head (thought it's gotten much less noticable) , and just a very minor bend/indentation. I finally talked to a urologist a few months ago and he prescribed uraxotral saying that it was probably my prostate acting up and that all nerves are actually located in the prostate (or something like that). It helped a little bit, but not completely. Could this possibly be peyronies?

I don't think so. MG

I am 58 and was diagnosed with Peyronies 3 years ago. One night I was normal, the next day a problem. Overnight it went from a 9 inch erection to a whopping 3 inches if I am lucky. It lost length and considerable girth. It also has a slight downward curvature. I have never experienced any pain whatsoever. My wife has since left me and I have felt so inadequate that I haven't even dated in 3 years. I feel the plaque on the bottom right side and it feels like a very hardened vein. When I was originally diagnosed my Dr. had a I couldn't care less attitude so I have felt lost ever since. If surgery is a possibility, who is the best?

Please see earlier forum entries below for websites offering geographically based referrals to experienced surgeons. MG

I had surgery for prostate cancer in January '05 and had a catheter for 10 days after the surgery. I began having nocturnal erections about 5 days into the catheter period and the doctor removed it early because of this (he had planned on leaving it for 14 days). Around January of this year I began noticing pain during erections and an upward curve in the penis. The curve became worse fairly rapidly and I went back to the urologist in March and he confirmed that I had Peronies. Is there a connection between the fact that my penis was trying to get erect while I was still on the catheter and now having Peronies? I remember it was painful when I had the nocturnal erections while still on the catheter and that my penis was forced into a compressed shape because there wasn't room for full extension due to the catheter. The doctor and the insurance company are saying the catheter and Peronies are not related. What do you think? I am about to start vacuum therapy and verapamil injections. I've been on colchicine and 400 mg of vitamin E since March. By the way, I had been taking the vitamin E for many years until January of this year and stopped because my primary doctor suggested it might not be a good idea given all the negative press about E. Since I knew nothing pf Peronies and had no problems that I was aware of, I stopped - which is about the same time the curvature and pain began. Coincidence?

There is an increased risk of PD in men undergoing radical prostatectomy for cancer. Whether vitamin E can prevent this is unkown. MG

I am 57 years old and just diagnosed with PD. My urologist seems extremely knowledgeable and I have a lot of trust in him. He has prescribed 1000 units of vitamin E once a day. I noticed in these postings, that the amount prescribed is usually 400. What is your opinion of such a large amount?

That is not really a large amount, but based on recent reports of cardiovascular effects of bigger doses, many urologists are reccommending 400 units per day. MG

I'm 49, diabetic for 30 yrs, blood pressure and cholesterol. I watch them all closely and have loads of energy. Recently I started experiencing ED, which I thought may happen and got a prescription of Levitra. Shortly after starting this I started noticing symptoms of Peyronies. Erect length is about half of previous, noticable reduction in diameter and a slight bend upwards at this point. Immediately started taking vitamin E. Can you recommend a urology specialist on Long Island and what can I take off the shelf to assist this to "fade away".

See below for entries regarding referral sites. Vitamin E is the only over the counter remedy commonly used for PD. MG

I am 58 years old and used to have a 6" penis. Peyronies changed all that. My penis is now 3.5" long and smaller in girth, a little thicker than my thumb. This "Peyronies Straitjacket" has left me with a penis that effectively is 25% of what it was. I am single. While some women in my life are sensitive to my condition, all have been disappointed. It has been a "deal breaker" with relationships with women that want a "normal" sexual relationship. There is no "hot banging sex" with a narrow 3 1/2" inch penis. There is no pride in sexual performance (intercourse). There really is no satisfying intercourse for me either, as the depth of stroke is down to 1" of movement, and the bend does not help either. Hardly satisfying for many women, and not satisfying for me at all either. While still full of testosterone, and the desire, intercourse is now hardly worth the effort. Disappointing for me and the women that I am with. It can be very difficult for a third date with a woman. At that time...when many couples begin to be intimate...there is a tremendous hesitation and perhaps avoidance with me. Is the woman able to be trusted with the knowledge of my microscopic penis? Will she simply give me a "later" and walk. Will she tell all her friends? Will I become a topic of entertainment? All these things have happened to me. Science and medicine will not give me my old penis back. Testosterone and desire are still there.... So there is a torment. There is nothing to help me. But one thing I do know....is the importance of knowing that I am not my penis. When we finally leave this earth....nothing of our body works. Age takes it's toll. For some it is a terrible toll, as in cancer and other life threatening diseases. It could be so much worse. I was affected with Peyronies 6 years ago. The passage of time helps with the acceptance.

Thanks for sharing your experience. Fortunately for others, the process is not always this devastating. MG

Ever since I acquired a rather mild case of Peyronies, I have noticed that the skin right under the head of my penis has become stretched and wrinkled in the flacid position. It is also quite red and irritated. Is that caused by the Peyronies or is it the result of a weeks course my doctor gave me of topical verapamil, which I stopped because of severe burning of the skin? At the same time, I am taking an anti-depressant which allows me to acheive an erection, but I can rarely ejaculate. Will that ability come back once I am off the anit-depressant?

Skin irritation is not part of PD - that is due to the topical medication. Yes, ejaculation will return when you stop the antidepressants. MG

I am 29 years old, and for quite some time I have experienced painful erections - but only when I am sleeping. I find myself waking up few times a night because of it. I have noticed a very slight curve to the left in my penis, but it is very minor. I have a very healthy libido, and I masterbate and I am sexually active. Could this be Peyronies? If not, any ideas?

This does not sound like PD to me, though an examination by a urologist might be a good idea. MG

 

July 2006

I injured my penis about a month ago by masturbating. At the beginning, my penis was semi-erect and I felt pain masturbating but I continued this time anyway for 4 or 5 seconds and then I stopped, became fully erect and masturbated to ejaculation. What I believe was happening was my penis head was bending a little back and forth because my penis naturally curves upwards a little. Felt some pain, not too severe for the next couple of days on the left side of my penis near the head. Masturbated again 3 days later, while fully erect and no pain while masturbating. However, the next week my penis hurt a lot and there was some small swelling and redness in the same area (front left). At the end of this week I went to the emergency room for fear that I ruptured my penis. On presentation, my penis was sore, not too painful, although painful to the touch on the left side. There was some slight redness in the area, although not to apparant after I had taken alleve. The emergency room doctor asked if I had an erection since the event, and I said yes. He examined me by hand and said he couldn't find anything. I asked him if I needed some other tests done or possible surgery and he said no, people who display ruptured penises have problems with erections. Two weeks later I saw a urologist who could not feel any scar or anything out of the ordinary, although I presented with pain and visible redness in the area. I took one Vitamin E pill as prescribed by the doctor that night and the next morning I noticed that my penis was bent markedly to the left in an almost erect state. Previous to this I noticed no bending of my erect penis, although it was bent sort in a flaccid state right at the tip due to the redness maybe. My question to you is, was my penis actually ruptured at the time of the presentation to the emergency room. What is causing this bent penis?

You did not rupture the penis; it would have been black & blue and swollen. There was probably a lesser degree of injury causing a peyronies-like condition. This well may improve, so I would not reccomend surgery at this time. MG

When I get an erection on the left side of my penis there are 2 very visible bands or lumps, <>3cm that appear to be in the erectile tissue, that span across the left side of the shaft which become bigger and harder when I get an erection and smaller as I am flaccid. I went to see a doctor about this problem in late 2005 and described it . He felt my flaccid penis where the area was and said it was scar tissue and said it would require surgery to fix if I wanted to get rid of it. I have no bending of my penis when erect but the fact that there are these two visible palpable band/lumps of tissue sometimes makrs me concerned. Sometimes they ache especially when I get an erection and touch them but the pain subsides when flaccid. Does this sound like Peyronies disease?

No. MG

i really dont rember any pain but my penis goes to the righ and has a twist to it. will this ruin my future sex life?

Unlikely, if the bend is less than 20 -30 degrees. MG

I was diagnosed with Peyronie’s disease about 30 years ago. Treatment with POTABA relieved the pain. Although left with a curvature of the penis, I have been able to have intercourse without pain. During the last few weeks I have been experiencing discomfort again. I haven’t experienced any recent trauma to the penis. Is it common for the disease symptoms to reappear after so many years of dormancy?

This is unusual. Based on your previous response to Potaba, I would consider re-starting it for 3 -4 months. MG

My doctor diagnosed PD 4 months ago. I have a hard ring of about an inch in lengh around the base of my penis which reduces the diameter by about 1/3rd and my length has reduced by half to around 3". I have not been sexually active for about 5 years. When my wife and I tried recently to have intercourse for the first time in years, it was difficult because of my lack of lenght. Is my length likely to improve on it's own?

Unfortunately, length lost due to PD is not usually recovered. MG

For as long as I can remember my penis has bent somewhat hard to the left. I've been reading on PD and I am truely hoping that it is not that. I haven't noticed any other symptoms so I'm hoping this is normal(I always assumed it was & my girl never said anything about it).

Yes it is, and it sounds like it works fine. MG

Has anyone had an experience with the ESWT Clinic in Canada? They use shockwave therapy.

There are several entries in the forum about ESWT. It doesn't work. MG

I have PD for 2 y, 45 degree bend up. I was taking Vit E for the first 6 months, and after these 6 months I am on Potaba until know (1.5 year). The 45 degree bend still exists. What you recommend ?

With that degree of bending, and the passage of 2 years, it would be reasonable to consider surgery (either nesbit or graft - see someone who does sufficient case volume.) MG

my penis is only slightly bent to the left. I noticed it was bent about 6 months ago. will it heal over time or should I seek treatment or advice from my doctor?

If it is truly slight, I would give it time to heal before seeking urological evaluation. MG

I am a 49 year old male who sustained a crack sound during intercourse about 3-4 months ago. As first I was sore but conti